首页 | 本学科首页   官方微博 | 高级检索  
文章检索
  按 检索   检索词:      
出版年份:   被引次数:   他引次数: 提示:输入*表示无穷大
  收费全文   687篇
  免费   154篇
  国内免费   18篇
耳鼻咽喉   4篇
儿科学   33篇
妇产科学   6篇
基础医学   149篇
口腔科学   17篇
临床医学   80篇
内科学   150篇
皮肤病学   8篇
神经病学   22篇
特种医学   180篇
外科学   47篇
综合类   55篇
预防医学   36篇
眼科学   4篇
药学   25篇
  1篇
肿瘤学   42篇
  2021年   5篇
  2018年   7篇
  2016年   6篇
  2015年   8篇
  2014年   7篇
  2013年   6篇
  2012年   14篇
  2011年   15篇
  2010年   11篇
  2009年   17篇
  2008年   10篇
  2007年   26篇
  2006年   18篇
  2005年   19篇
  2004年   17篇
  2003年   19篇
  2002年   8篇
  2001年   19篇
  2000年   6篇
  1999年   11篇
  1998年   27篇
  1997年   26篇
  1996年   19篇
  1995年   26篇
  1994年   26篇
  1993年   36篇
  1992年   16篇
  1991年   12篇
  1990年   19篇
  1989年   25篇
  1988年   31篇
  1987年   41篇
  1986年   31篇
  1985年   29篇
  1984年   19篇
  1983年   31篇
  1982年   30篇
  1981年   26篇
  1980年   22篇
  1979年   16篇
  1978年   16篇
  1977年   11篇
  1976年   6篇
  1975年   8篇
  1974年   5篇
  1973年   6篇
  1971年   4篇
  1970年   7篇
  1969年   6篇
  1968年   8篇
排序方式: 共有859条查询结果,搜索用时 437 毫秒
1.
2.
3.
Ten thrombocytopenic patients (platelets < 10–24 × 10(9)/L) who were refractory to platelet transfusion were investigated for their responsiveness to staphylococcal protein A column therapy. Nine patients had previously been treated with steroids, intravenous immune globulin, and/or other forms of immunosuppressive therapy without improvement in their transfusion response. All patients were receiving multiple platelet transfusions without achieving 1-hour corrected count increments (CCIs) > or = 7500. Eight patients had antibodies that reacted with platelets and were directed against HLA class I antigens, ABO antigens, and/or platelet-specific alloantigens. Plasma (500-2000 mL) from each patient was passed over a protein A silica gel column and then returned to the patient. Patients received from 1 to 14 treatments. A positive response to protein A therapy was defined as at least a doubling of the pretreatment platelet count and/or two successive 10- to 120-minute posttransfusion CCIs > or = 7500. Following plasma treatments, 6 of 10 patients responded with daily platelet counts that averaged 48 +/− 11 × 10(9) per L as compared with counts of 16 +/− 7 × 10(9) per L (p < 0.0005) before treatment. Posttransfusion CCI values determined in four of these patients averaged 2480 +/− 810 and 10,010 +/− 3540 (p < 0.005) before and after treatment, respectively. In contrast, among the four unresponsive patients, platelet counts averaged 10 +/− 9 and 13 +/− 10 × 10(9) per L (p = NS), respectively, while posttransfusion CCIs were 700 +/− 1410 and 1520 +/− 2460 (p = NS), respectively.(ABSTRACT TRUNCATED AT 250 WORDS)  相似文献   
4.
Results of clinical, contrast enema (CE), and computed tomographic (CT) examinations in 39 patients with perforated colorectal neoplasms were retrospectively reviewed. Twenty patients were toxemic at initial presentation, but in only four patients was the diagnosis of perforated colorectal neoplasm initially suspected clinically. CE study was performed in 22 patients and enabled the diagnosis of perforated neoplasm in 11 cases, neoplasm alone in eight, and neither neoplasm nor perforation in three. CT was performed in 38 patients and enabled the diagnosis of perforated neoplasm in 36; pericolic phlegmon but no mass lesion was evident in two. In 16 patients, CT also demonstrated metastatic disease. Because of its reliability in establishing the diagnosis and staging the extent of the inflammatory and neoplastic disease, CT is indicated in cases of suspected or proved perforated colorectal neoplasm and in cases in which CE study findings are indeterminate or suggestive of perforated neoplasm.  相似文献   
5.
6.
The Childrens Cancer Study Group evaluated daily oral 13-cis-retinoic acid to determine its therapeutic efficacy in 28 children with advanced neuroblastoma refractory to conventional therapy. Cheilitis and fissured lips were the most common side effects; however, fewer than 50% of the patients experienced any toxicity. Two of twenty-two evaluable children demonstrated positive response to therapy. In one case, a child received the drug for 11 months. Seventeen patients demonstrated progressive disease within 28 days of the start of treatment. Three other patients with stable disease, or removed from study at day 28, were considered nonresponsive. Our data demonstrate that, when given as a single daily oral dose of 100 mg/m2, 13-cis-retinoic acid does not have significant activity in children with advanced neuroblastoma. © 1992 Wiley-Liss, Inc.  相似文献   
7.
The anonymity of the North American culture as well as the loss of the extended family has left many persons without emotional or spiritual resources. A religious congregation can be a source of support to the bereaved. This article gives practical details in the organizing of such a ministry and the training necessary for the community members who will be serving the bereaved.  相似文献   
8.
9.
10.
设为首页 | 免责声明 | 关于勤云 | 加入收藏

Copyright©北京勤云科技发展有限公司  京ICP备09084417号