全文获取类型
收费全文 | 612篇 |
免费 | 43篇 |
国内免费 | 3篇 |
专业分类
耳鼻咽喉 | 17篇 |
儿科学 | 45篇 |
妇产科学 | 13篇 |
基础医学 | 52篇 |
口腔科学 | 16篇 |
临床医学 | 67篇 |
内科学 | 141篇 |
皮肤病学 | 29篇 |
神经病学 | 66篇 |
特种医学 | 15篇 |
外科学 | 100篇 |
综合类 | 12篇 |
预防医学 | 17篇 |
眼科学 | 11篇 |
药学 | 37篇 |
中国医学 | 3篇 |
肿瘤学 | 17篇 |
出版年
2023年 | 6篇 |
2022年 | 9篇 |
2021年 | 21篇 |
2020年 | 11篇 |
2019年 | 13篇 |
2018年 | 15篇 |
2017年 | 17篇 |
2016年 | 27篇 |
2015年 | 40篇 |
2014年 | 34篇 |
2013年 | 36篇 |
2012年 | 49篇 |
2011年 | 47篇 |
2010年 | 35篇 |
2009年 | 30篇 |
2008年 | 50篇 |
2007年 | 53篇 |
2006年 | 40篇 |
2005年 | 37篇 |
2004年 | 25篇 |
2003年 | 23篇 |
2002年 | 24篇 |
2001年 | 3篇 |
2000年 | 3篇 |
1999年 | 2篇 |
1998年 | 2篇 |
1996年 | 1篇 |
1990年 | 3篇 |
1980年 | 1篇 |
1977年 | 1篇 |
排序方式: 共有658条查询结果,搜索用时 15 毫秒
1.
2.
3.
When tracking moving visual stimuli, primates orient their visual axis by combining two kinds of eye movements, smooth pursuit and saccades, that have very different dynamics. Yet, the mechanisms that govern the decision to switch from one type of eye movement to the other are still poorly understood, even though they could bring a significant contribution to the understanding of how the CNS combines different kinds of control strategies to achieve a common motor and sensory goal. In this study, we investigated the oculomotor responses to a large range of different combinations of position error and velocity error during visual tracking of moving stimuli in humans. We found that the oculomotor system uses a prediction of the time at which the eye trajectory will cross the target, defined as the "eye crossing time" (T(XE)). The eye crossing time, which depends on both position error and velocity error, is the criterion used to switch between smooth and saccadic pursuit, i.e., to trigger catch-up saccades. On average, for T(XE) between 40 and 180 ms, no saccade is triggered and target tracking remains purely smooth. Conversely, when T(XE) becomes smaller than 40 ms or larger than 180 ms, a saccade is triggered after a short latency (around 125 ms). 相似文献
4.
Mundgesundheitskompetenz von Menschen mit Migrationshintergrund – Erste Auswertungen der MuMi-Studie
Spinler Kristin Weil Marie-Theres Valdez Richelle Walther Carolin Dingoyan Demet Seedorf Udo Heydecke Guido Lieske Berit Kofahl Christopher Aarabi Ghazal 《Bundesgesundheitsblatt, Gesundheitsforschung, Gesundheitsschutz》2021,64(8):977-985
Bundesgesundheitsblatt - Gesundheitsforschung - Gesundheitsschutz - Erste Studien heben den Migrationshintergrund von Menschen in Deutschland als eigenständigen Risikofaktor für eine... 相似文献
5.
6.
Salbutamol or mist in acute bronchiolitis 总被引:1,自引:0,他引:1
Demet Can GÜLten Nan GÜRol Yendur Resmiye Oral Lker GÜNay 《Pediatrics international》1998,40(3):252-255
Abstract Background : The role of bronchodilators in the treatment of bronchiolitis remains controversial.
Methods : A double-blind, placebo controlled trial was performed to evaluate the clinical response to nebulized salbutamol. One hundred and fifty-six infants aged between 7 weeks and 24 months who had had an episode of wheezing and other signs and symptoms of bronchiolitis were randomized to three groups as follows: (i) nebulized salbutamol was administered to 52 patients in group I at a dose of 0.15 mg/kg in 2 mL saline; (ii) saline was nebulized to 52 patients in group II and (iii) in group III 52 patients received mist in a tent. All three groups were administered oxygen during the procedures. Treatment was repeated with the same agent after 30 min if the respiratory score was 5 or more. Respiratory rate, heart rate, oxygen saturation and presence of cyanosis, wheezing, retractions were recorded before and after each treatment.
Results : The decrease in the respiratory score was 5.2 ± 1.8, 0.82 ± 2.4 and 1.7 ± 1.3 in group I, II and III, respectively. The decrease in group I was significantly higher than in the other groups. Heart rate was similar between groups. Oxygen saturation decreased in group I without reaching statistical significance.
Conclusions: Salbutamol was shown to be effective and safe in the treatment of acute bronchiolitis. 相似文献
Methods : A double-blind, placebo controlled trial was performed to evaluate the clinical response to nebulized salbutamol. One hundred and fifty-six infants aged between 7 weeks and 24 months who had had an episode of wheezing and other signs and symptoms of bronchiolitis were randomized to three groups as follows: (i) nebulized salbutamol was administered to 52 patients in group I at a dose of 0.15 mg/kg in 2 mL saline; (ii) saline was nebulized to 52 patients in group II and (iii) in group III 52 patients received mist in a tent. All three groups were administered oxygen during the procedures. Treatment was repeated with the same agent after 30 min if the respiratory score was 5 or more. Respiratory rate, heart rate, oxygen saturation and presence of cyanosis, wheezing, retractions were recorded before and after each treatment.
Results : The decrease in the respiratory score was 5.2 ± 1.8, 0.82 ± 2.4 and 1.7 ± 1.3 in group I, II and III, respectively. The decrease in group I was significantly higher than in the other groups. Heart rate was similar between groups. Oxygen saturation decreased in group I without reaching statistical significance.
Conclusions: Salbutamol was shown to be effective and safe in the treatment of acute bronchiolitis. 相似文献
7.
8.
Aydin Çiledağ Hülya Deniz Serpil Eledağ Canan Özkal Nurşen Düzgün Selim Erekul Demet Karnak 《Rheumatology international》2012,32(2):451-455
Churg–Strauss syndrome (CSS) is a rare type of necrotizing vasculitis affecting small to medium-sized vessels typically characterized
by asthma, lung infiltrates, necrotizing granulomas and hypereosinophilia. Herein, we describe a case of CSS presenting severe
and aggressive course. A 35-year-old male patient with weight loss, dyspepsia, dyspnea and hemoptysis was admitted. The laboratory
analyses indicated a remarkable eosinophilia, elevated levels of serum total IgE and positive cANCA. Thorax CT findings were
suggestive of alveolar hemorrhage. Bronchoalveolar lavage revealed alveolar hemorrhage with eosinophilia and transbronchial
lung biopsy showed eosinophilic vasculitis. Cardiac enzymes were increased and murmurs were audible revealing cardiomyopathy
proven by echocardiography. Pulse cyclophosphamide and methyl prednisolone was immediately started. On the 21st day, intestinal
perforation developed and urgent surgery was performed. During a follow-up, although a radiological improvement was observed
in the chest X-ray, cardiac failure, peripheral neuropathy and skin lesions developed and high-dose intravenous immunoglobulin
and anti-TNF therapy (adalimumab) were applied. Despite the therapy, he died from heart failure and septicemia at 68th day
of therapy. 相似文献
9.
Asli Inci Pinar Gencpinar Demet Orhan Gulbahar Uzun Sebahat Ozdem Anıl Aktaş Samur Senay Haspolat Özgür Duman 《Brain & development》2013
Convulsions are one of the frequently seen problems for a neurologist in the daily routine. It is difficult to distinguish the seizure from pseudo-seizure because of lack of conclusive tests. The aim of this study is to investigate the relationship between seizure types and seizure periods by studying IMA serum levels in children having seizure. Two groups were included (patients and control) in our study. The patient group consisted of the children admitted to Pediatric Emergency Care during January 2008–January 2010 with seizure and the control group consisted of healthy children. Serum Ischemia modified albumin (IMA) level in the group having seizures was 99.7 and 83.2 U/ml in the control group. In the comparison of the patient and control groups, significant differences were found between their IMA values (p = 0.000). There was a significant difference between IMA values of the group having generalized tonic–clonic seizures and those of the control group (p = 0.001). In comparison of the IMA values of the group having febrile convulsions and those of the control group, a significant difference was determined (p = 0.011). It has been shown that if the seizure was prolonged over 5 min, IMA level increased, and there was a significant difference between the groups experiencing over 5 min of seizures and the groups experiencing less than 5 min of seizures (p = 0.001). An increase in IMA levels in febrile convulsion supports the hypoxia development in the brain during the seizure. Serum IMA levels increased with the elongation of the seizure period and may be an indicator for status epilepticus. 相似文献
10.