收费全文 | 4009篇 |
免费 | 292篇 |
国内免费 | 2篇 |
耳鼻咽喉 | 19篇 |
儿科学 | 346篇 |
妇产科学 | 99篇 |
基础医学 | 492篇 |
口腔科学 | 102篇 |
临床医学 | 437篇 |
内科学 | 914篇 |
皮肤病学 | 45篇 |
神经病学 | 273篇 |
特种医学 | 228篇 |
外科学 | 390篇 |
综合类 | 60篇 |
一般理论 | 14篇 |
预防医学 | 441篇 |
眼科学 | 51篇 |
药学 | 220篇 |
中国医学 | 1篇 |
肿瘤学 | 171篇 |
2022年 | 31篇 |
2021年 | 53篇 |
2020年 | 29篇 |
2019年 | 57篇 |
2018年 | 81篇 |
2017年 | 52篇 |
2016年 | 69篇 |
2015年 | 84篇 |
2014年 | 106篇 |
2013年 | 130篇 |
2012年 | 206篇 |
2011年 | 214篇 |
2010年 | 130篇 |
2009年 | 129篇 |
2008年 | 178篇 |
2007年 | 188篇 |
2006年 | 214篇 |
2005年 | 184篇 |
2004年 | 174篇 |
2003年 | 129篇 |
2002年 | 111篇 |
2001年 | 124篇 |
2000年 | 122篇 |
1999年 | 107篇 |
1998年 | 58篇 |
1997年 | 63篇 |
1996年 | 56篇 |
1995年 | 47篇 |
1994年 | 55篇 |
1993年 | 39篇 |
1992年 | 82篇 |
1991年 | 70篇 |
1990年 | 64篇 |
1989年 | 88篇 |
1988年 | 67篇 |
1987年 | 68篇 |
1986年 | 59篇 |
1985年 | 68篇 |
1984年 | 55篇 |
1983年 | 46篇 |
1982年 | 32篇 |
1981年 | 28篇 |
1980年 | 29篇 |
1979年 | 39篇 |
1978年 | 34篇 |
1977年 | 26篇 |
1976年 | 18篇 |
1975年 | 20篇 |
1974年 | 31篇 |
1973年 | 23篇 |
Methods: Data from 1392 girls, aged 9 to 10 at baseline and followed for 10?years, in the National Heart, Lung, and Blood Institute’s National Growth and Health Study were used to examine the association between usual egg intake alone and in combination with other healthy lifestyle factors and late adolescent lipid levels, fasting glucose, and insulin resistance, measured as homeostasis model assessment of insulin resistance (HOMA-IR). Diet was assessed using 3-day food records during eight examination cycles. Girls were classified according to usual weekly egg intake, ages 9–17?years:?<1 egg/wk (n?=?361), 1 to <3 eggs/wk (n?=?703), and ≥3 eggs/wk (n?=?328). Analysis of covariance modeling was used to control for confounding by other behavioral and biological risk factors.
Results: Girls with low, moderate, and high egg intakes had adjusted low-density lipoprotein cholesterol levels of 99.7, 98.8, and 95.5 mg/dL, respectively (p?=?0.0778). In combination with higher intakes of fiber, dairy, or fruits and vegetables, these beneficial effects were stronger and statistically significant. There was no evidence that ≥3 eggs/wk had an adverse effect on lipids, glucose, or HOMA-IR. More active girls who consumed ≥3 eggs/wk had the lowest levels of insulin resistance.
Conclusion: These results suggest that eggs may be included as part of a healthy adolescent diet without adverse effects on glucose, lipid levels, or insulin resistance. 相似文献
BACKGROUND
Online physician rating websites are increasingly used by patients to evaluate their doctors. The purpose of this investigation was to evaluate factors associated with better spine surgeon ratings.METHODS
Orthopedic spine surgeons were randomly selected from the North American Spine Society directory utilizing a random number generator. Surgeon profiles on three physician rating websites, namely, www.HealthGrades.com, www.Vitals.com, and www.RateMDs.com, were analyzed to gather qualitative and quantitative data on patients’ perceptions of the surgeons. Independent variables from the websites were analyzed in relation to overall physician or patient satisfaction rating. Comments were coded by subject into following three categories: professional competence, bedside manner, and practice characteristics.RESULTS
A total of 250 surgeons were evaluated, and 92% (n=230) of these doctors had at least one rating among the three websites. The surgeons with a higher average rating had significantly better trust (p<.01), scheduling (p<.01), staff (p<.01), helpfulness (p<.01), and punctuality (p<.01) scores but significantly less experience (p<.05). A linear regression model for the average rating of each surgeon (R2 value=0.754) yielded only following three significant variables: trustworthiness (p<.01), experience match (p<.05), and the average number of negative comments on surgeon's professional competence (p<.05). Trustworthiness (β=0.749) was the strongest predictor variable of physician rating, followed by the number of negative professional competence comments (β=?0.132) and experience match (β=?0.112).CONCLUSIONS
This investigation assessed spine surgeon online patient ratings and categorized factors that patients associate with quality care. Trustworthiness was the most significant predictor of positive ratings, whereas ease of scheduling, quality of staff, helpfulness, and punctuality were also associated with higher patient ratings. Understanding what patients value may help optimize care of spine surgery patients. 相似文献Methods Thirteen patients with 21 biopsy-proven tumours (4 of 21 relapses after prior surgery) were included. After 2–5 weeks (median, 3) of daily 5% imiquimod cream application, the tumours were treated by liquid N
Results Nineteen of 21 tumours responded promptly to immunocryosurgery; two tumours required additional treatment cycles to clear. Thus, the clinical clearance rate was 100%. Only 1 of 21(5%) tumour relapsed after at least 18 months of follow-up (cumulative efficacy: 95%).
Conclusions 'Immunocryosurgery' is a promising non-surgical combination modality to treat 'high-risk-for-recurrence BCCs'. Initial evidence is suggestive of an at least additive effect of the two combined modalities. Further studies comparing immunocryosurgery directly with cryosurgery and imiquimod monotherapies will confirm the reported results. 相似文献