首页 | 本学科首页   官方微博 | 高级检索  
文章检索
  按 检索   检索词:      
出版年份:   被引次数:   他引次数: 提示:输入*表示无穷大
  收费全文   519篇
  免费   27篇
  国内免费   2篇
耳鼻咽喉   5篇
儿科学   11篇
妇产科学   21篇
基础医学   32篇
口腔科学   14篇
临床医学   45篇
内科学   116篇
皮肤病学   2篇
神经病学   9篇
特种医学   70篇
外科学   62篇
综合类   43篇
预防医学   11篇
眼科学   13篇
药学   68篇
  1篇
肿瘤学   25篇
  2023年   5篇
  2022年   4篇
  2021年   5篇
  2020年   7篇
  2019年   14篇
  2018年   9篇
  2017年   9篇
  2016年   9篇
  2015年   16篇
  2014年   18篇
  2013年   15篇
  2012年   26篇
  2011年   25篇
  2010年   16篇
  2009年   19篇
  2008年   26篇
  2007年   23篇
  2006年   27篇
  2005年   22篇
  2004年   26篇
  2003年   14篇
  2002年   11篇
  2001年   20篇
  2000年   18篇
  1999年   12篇
  1998年   14篇
  1997年   18篇
  1996年   16篇
  1995年   10篇
  1994年   13篇
  1993年   15篇
  1992年   10篇
  1991年   9篇
  1990年   4篇
  1989年   14篇
  1988年   6篇
  1987年   6篇
  1986年   5篇
  1983年   1篇
  1981年   2篇
  1980年   2篇
  1978年   3篇
  1977年   1篇
  1976年   2篇
  1970年   1篇
排序方式: 共有548条查询结果,搜索用时 15 毫秒
1.
2.
3.
Complications following free tissue transfer have been well established in the literature. Common and rare causes of free flap failure must be addressed by the treating surgeon when microvascular patency is threatened. With the evolution and prevalence of microsurgery, ‘rare’ causes of free flap failure will become increasingly frequent. A high index of suspicion must be established in patients with multiple failed operative interventions. A case of recurrent free flap failure secondary to heparin-induced thrombocytopenia is presented in a patient with a history of squamous cell carcinoma of the floor of the mouth, and a long-standing history of alcohol and tobacco consumption.  相似文献   
4.
5.
Laser-Doppler flowmetry has been used to study the skin microcirculation in 20 normal limbs and 80 limbs of patients with venous hypertension and leg ulceration due to deep venous reflux. It was found that limbs with venous hypertension had a high skin resting blood flow (BRF) and an impaired veno-arteriolar reflex (VR). There was a marked improvement in both BRF and VR after elastic compression for three weeks and an association between this improvement and the rate of healing of the leg ulcers. The results indicate that elastic compression may affect the microcirculation even though it does not alter the venous pressure measurements when the elastic stockings are removed.  相似文献   
6.
7.
The relationship between the digoxin elimination parameter (A%) and creatinine clearance (CLCr) was determined, from blood level data of 160 hospital patients receiving digoxin tablets. The linear regression equation obtained, which varied only slightly from that reported by Jelliffe previously, was used to predict serum digoxin concentrations in 140 patients of four age groups (50–60, 60–70, 70–80 and 80–90 years). The predictions made were found to be less biased and more precise, irrespective of the age of the patients, than those produced using another predictive method known as Dobbs method. However, correlation coefficients of predicted versus measured serum digoxin concentrations for each method did not differ significantly and frequency distribution analyses of prediction errors gave poor results (up to 63% only). Therefore, neither method can be considered to be superior to the other nor can they be said to ensure accurate predictions of serum digoxin concentrations.  相似文献   
8.
9.
Vascularization is a prominent event during corpus luteum formation, providing low density lipoproteins for steroid biosynthesis and enabling transport of secreted steroids. The process of vascularization is controlled by specific regulators. Vascular endothelial growth factor (VEGF), otherwise named vascular permeability factor (VPF), induces endothelial cell proliferation as well as angiogenesis in vivo and increases capillary permeability. Here we report the expression of VEGF/VPF mRNA by cultured human luteinized granulosa cells (GC) for at least 10 days. Without HCG VEGF/VPF expression declined after day 4 and by day 10 was reduced to approximately 30% of the value at day 4. However, after culture in the presence of 1 U/ml human chorionic gonadotrophin (HCG), expression of VEGF/VPF mRNA by GC was four times greater than control experiments by day 10, and increased 100% from day 4 to day 10. Simultaneously, HCG supplementation increased VEGF/VPF secretion by GC. Medium VEGF/VPF on day 3 was 13 pM without and 11 pM with HCG. Medium VEGF/VPF on day 10 was 6 pM without HCG and 29 pM with HCG. These results suggest that vascularization of the corpus luteum is induced by HCG-mediated effects of VEGF/VPF.   相似文献   
10.
Lesions of the articular surfaces of the knee have been managed by various techniques over the last 50 years. Surgical management has involved: excising the damaged area, refashioning the underlying bone to produce a fibrous response, and introducing allograft, autograft and synthetic materials to encourage a repair matrix. The techniques and their pitfalls are reviewed and discussed, and suggestions made as to the direction of future studies for the repair of osteochondral lesions in the painful knee.  相似文献   
设为首页 | 免责声明 | 关于勤云 | 加入收藏

Copyright©北京勤云科技发展有限公司  京ICP备09084417号