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1.
SB Miranda† O Lupi‡ E Lucas† 《Journal of the European Academy of Dermatology and Venereology》2004,18(5):622-625
Pityriasis rosea (PR) is a relatively common disease although its aetiology has not yet been identified. It occurs worldwide and there is no racial susceptibility factor. It usually affects teenagers and young adults between 10 and 35 years of age. Typical PR is much easier to diagnose than the rare atypical forms. We report a rare case of vesicular PR in a black woman who had vesicular lesions limited to her palms and soles in addition to regular typical lesions. We devised an efficient oral erythromycin treatment for this patient. 相似文献
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进一步研究了抗三尖杉酯碱的HL-60细胞(HR20)抗细胞凋亡的机制及该抗性和抗药性的关系。结果表明,环孢菌素A(CsA)20,10μg·ml ̄(-1)诱导HL-60细胞发生凋亡,而阻断HR20细胞于G_1期,就不能诱导细胞发生凋亡。低浓度的CsA明显增加柔红霉素在HR20细胞内的积聚,其逆转抗药性作用与阻断细胞周期运行无关。CsA10μg·ml ̄(-1)处理HR20细胞,可引起50kDa的蛋白质高度磷酸化。结果提示:环孢菌素A阻断抗三尖杉酯碱的HL-60细胞于G_1期,而诱导敏感的HL-60细胞发生凋亡,其阻断作用与抗药性无关 相似文献
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S. B. Cheknev Ya. G. Ashmanova O. L. Latysheva S. Zh. Toksambaeva E. B. Mysyakin A. Ya. Kul'berg 《Bulletin of experimental biology and medicine》1994,118(1):751-754
The cytotoxicity of natural killer cells (NK) against3H-uridine-labeled target cells (TC, human erythromyeloleukosis cells K-562) and the intensity of conjugate formation in the
NK:TC system in the presence of γ-interferon, C-reactive protein, and human fibronectin are studiedin vitro in 14 patients with multiple sclerosis. It is shown that γ-interferon and C-reactive protein decrease the cytotoxic activity
of NK with a simultaneous stimulation of conjugate formation in the NK:TC system. The correlation between the studied parameters
becomes weaker. Human fibronectin induces collateral changes in the activity of NK and in the number of effector:target conjugates
formed in the natural cytotoxicity reaction.
Translated fromByulleten' Eksperimental'noi Biologii i Meditsiny, Vol. 118, N
o
7, pp. 67–70, July, 1994 相似文献
8.
Needle biopsy of renal allografts: comparison of two techniques 总被引:2,自引:0,他引:2
Bogan ML; Kopecky KK; Kraft JL; Holladay AO; Filo RS; Leapman SB; Thomalla JV 《Radiology》1990,174(1):273-275
Two techniques for renal allograft biopsy were retrospectively evaluated to compare relative safety and efficacy. After ultrasound (US) localization of the kidney and biopsy with a hand-held 14-gauge cutting needle, an adequate specimen was obtained in 74 of 77 cases (96%). Major complications occurred in six of these 77 cases (8%). One hundred four biopsies were performed by using a smaller 18-gauge cutting needle with a spring-loaded biopsy "gun" and real-time US guidance. With this newer technique, specimens adequate for diagnosis were obtained in 99 biopsies (95%). There was a single major complication with this technique (1%). The 18-gauge needle with real-time US guidance yields comparably adequate specimens with a lower frequency of complications. 相似文献
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Cheknev SB 《Vestnik Rossi?sko? akademii meditsinskikh nauk / Rossi?skaia akademiia meditsinskikh nauk》1999,(2):10-15
Whether the redox active compounds that are able to generate and capture free oxygen radicals utilized in natural cytotoxicity (NCT) are involved in the provision and control of NCT in the body of man and animals is discussed. Evidence is given for the participation of endogenous metal-binding peptido(proteo)glycans (MBPPG) in the establishment and maintenance of regulatory balance in the complex of NCT reactions. Cyanobacterial exometabolites and their related metal-binding amphipathic compounds yielded in the exosystem was substantiated to be involved in the rational limitation of lymphocytic cytotoxicity. The findings suggest that exogenous redox active microbial products exert their action on NCT cells by changing the rate of generation and capture of free oxygen radicals by exogenous MBPPG. 相似文献
10.
分娩期连续电子胎心监护用于胎儿评估 总被引:1,自引:0,他引:1
1背景 在美国,每4例孕妇中有3例在产群中及分娩时使用电子胎儿监护(EFM)(NCHS1993)。1989年,美国妇产科学院(ACOG1989)发表了一项声明,对于低危妊娠既可使用EFM,也可使用间断性胎心听诊;但是,美国预防保健委员会(USPSTF1989)和加拿大的定期健康检查委员会(CTFPHE1994)对高危妊娠仍保留使用EFM。尽管有人对EFM的效果和安全性表示担忧(Thacker 1987:Thacker 1995), 相似文献