全文获取类型
收费全文 | 13880篇 |
免费 | 997篇 |
国内免费 | 41篇 |
专业分类
耳鼻咽喉 | 187篇 |
儿科学 | 344篇 |
妇产科学 | 235篇 |
基础医学 | 1908篇 |
口腔科学 | 1195篇 |
临床医学 | 1109篇 |
内科学 | 2885篇 |
皮肤病学 | 285篇 |
神经病学 | 1043篇 |
特种医学 | 382篇 |
外国民族医学 | 1篇 |
外科学 | 1696篇 |
综合类 | 64篇 |
预防医学 | 1297篇 |
眼科学 | 279篇 |
药学 | 913篇 |
中国医学 | 92篇 |
肿瘤学 | 1003篇 |
出版年
2023年 | 106篇 |
2022年 | 270篇 |
2021年 | 453篇 |
2020年 | 314篇 |
2019年 | 460篇 |
2018年 | 559篇 |
2017年 | 357篇 |
2016年 | 389篇 |
2015年 | 470篇 |
2014年 | 620篇 |
2013年 | 713篇 |
2012年 | 984篇 |
2011年 | 1078篇 |
2010年 | 557篇 |
2009年 | 498篇 |
2008年 | 727篇 |
2007年 | 773篇 |
2006年 | 625篇 |
2005年 | 561篇 |
2004年 | 482篇 |
2003年 | 405篇 |
2002年 | 400篇 |
2001年 | 307篇 |
2000年 | 324篇 |
1999年 | 271篇 |
1998年 | 94篇 |
1997年 | 73篇 |
1996年 | 56篇 |
1995年 | 61篇 |
1994年 | 70篇 |
1993年 | 63篇 |
1992年 | 152篇 |
1991年 | 167篇 |
1990年 | 136篇 |
1989年 | 161篇 |
1988年 | 106篇 |
1987年 | 121篇 |
1986年 | 102篇 |
1985年 | 78篇 |
1984年 | 87篇 |
1983年 | 51篇 |
1982年 | 54篇 |
1981年 | 45篇 |
1980年 | 36篇 |
1979年 | 61篇 |
1977年 | 46篇 |
1976年 | 44篇 |
1971年 | 39篇 |
1970年 | 38篇 |
1968年 | 38篇 |
排序方式: 共有10000条查询结果,搜索用时 15 毫秒
1.
Alejandra Gordillo Hernández Eduardo Dominguez-Adame Lanuza Auxiliadora Cano Matias Rosario Perez Huertas Katherine Maria Gallardo Rodriguez Purificacion Gallinato Perez Fernando Oliva Mompean 《World journal of gastrointestinal surgery》2015,7(8):170-173
Gangliocytic paragangliomas are rare tumors that almost exclusively occur within the second portion of the duodenum. Although these tumors generally have a benign clinical course, they have the potential to recur or metastasize to regional lymph nodes. The case report presented here describes a 57-year-old female patient with melena, progressive asthenia, anemia, and a mass in the second-third portion of the duodenum that was treated by local excision. The patient was diagnosed with a friable bleeding tumor. The histologic analysis showed that the tumor was a 4 cm gangliocytic paraganglioma without a malignant cell pattern. In the absence of local invasion or distant metastasis, endoscopic resection represents a feasible, curative therapy. Although endoscopic polypectomy is currently considered the treatment of choice, it is not recommended if the size of the tumor is > 3 cm and/or there is active or recent bleeding. Patients diagnosed with a gangliocytic paraganglioma should be closely followed-up for possible local recurrence. 相似文献
2.
3.
Joseane Balan Da Silva Gleison Daion Piovezana Bossolani Camila Piva Greicy Brisa Malaquias Dias Jancarlo Gomes Ferreira Diogo Francisco Rossoni 《International journal of environmental health research》2016,26(5-6):578-588
The spatial distribution of enteroparasitosis in an indigenous village from Paraná was evaluated to identify areas of risk for these infections. A cross-sectional study (from November 2010 to June 2011) was performed using Three Faecal Test® and Kato &; Katz method and a questionnaire on housing and hygiene conditions was administered. Local geostatistical analyses were performed to determine the spatial distribution of intestinal parasitic infections. The overall prevalence of enteroparasites was 67.2?% (457/680), and the most prevalent taxa were Ascaris lumbricoides (48.8?%) and Trichuris trichiura (44.7?%). The prevalence of heavy infection by soil-transmitted helminths was 3.6?% and the families lived in houses with an average of 5.1 residents and < 2 bedrooms per household. The average number of species per individual present spatial heterogeneity with the highest values (≥0.8) in areas with high clustering of residences. The visualization of the spatial distribution of intestinal parasites in this indigenous village is an important contribution to determining health risk areas and planning decisions and services. 相似文献
4.
5.
The antiproliferative, cytotoxic and apoptogenic activities of Bufo melanostictus (Indian common toad) skin extract (TSE) on U937 and K562 leukemic cell line has been investigated. TSE significantly (P<0.001) reduced the time-dependent cell proliferation and decreased MTT values in U937 and K562 cells. TSE (IC50 doses) suppressed the proliferating cell nuclear antigen expression in both the cells. It was demonstrated that, TSE (IC50 doses) primarily arrested the U937 and K562 cells at G1 phase of the cell cycle. Confocal microscopy showed the altered fragmented nuclei and apoptotic bodies formation in TSE (IC50 doses) treated U937 and K562 cells. Membrane blebbing, cell surface shrinkage and perforation were observed through scanning electron microscope. TSE-induced DNA fragmentation in U937 and K562 cells was reflected in single-cell gel electrophoresis. TSE significantly (P<0.001) increase the length-width ratio of DNA mass as compared to control in comet assay. The flow cytometric analysis of annexin-V binding to the cancer cells further supported the apoptotogenic activity of TSE. The effect of TSE on normal human peripheral blood mononuclear cells viability and cytotoxicity was studied in culture and found to be less cytotoxic than on the U937 and K562 cells. The findings from the present study suggested that TSE might possess potent antineoplastic agent having antiproliferative, cytotoxic and apoptogenic activity against U937 and K562 myeloid leukemic cells. 相似文献
6.
A. Perez S. E. Clements E. Benton A. Robson B. Bhogal C. M. Stefanato D. McGibbon 《Clinical and experimental dermatology》2009,34(8):e931-e933
We report a case of localized bullous pemphigoid (BP) in a woman patient with primary lymphoedema tarda. There is only one previous case reported of localized pemphigoid in an area of lymphoedema, this being of the cicatricial variant. Slow circulation in the lymphatic vessels, increased capillary permeability with preferential localization of antibodies in the area, and potential cleavage of the epidermal junction due to increased hydrostatic pressure leading to autoimmunity, have all been advocated as possible pathogenic mechanisms. Nevertheless, we consider that the mechanism by which localized pemphigoid arises on lymphoedema remains elusive, based on a previous case of generalized BP sparing an area of postsurgical lymphoedema. 相似文献
7.
8.
9.
S. Regnier Z. Ouagari Z. L. Perez N. Veziris F. Bricaire E. Caumes 《Clinical and experimental dermatology》2009,34(8):e690-e692
We report the case of a patient infected with human immunodeficiency virus who presented with fever and a disseminated papulous eruption, diagnosed as cutaneous miliary tuberculosis. The diagnosis was made by histological examination of a skin biopsy, which showed numerous acid‐fast bacilli. A culture grown from a skin biopsy isolated a resistant Mycobacterium tuberculosis strain. The papules disappeared within a few days after starting treatment with pyrazinamide, isoniazid and moxifloxacin. 相似文献
10.
Coronary artery bypass grafts: visualization with MR imaging 总被引:1,自引:0,他引:1