全文获取类型
收费全文 | 188篇 |
免费 | 24篇 |
专业分类
耳鼻咽喉 | 3篇 |
儿科学 | 7篇 |
基础医学 | 31篇 |
口腔科学 | 4篇 |
临床医学 | 23篇 |
内科学 | 50篇 |
皮肤病学 | 2篇 |
神经病学 | 14篇 |
特种医学 | 3篇 |
外科学 | 20篇 |
综合类 | 13篇 |
预防医学 | 23篇 |
眼科学 | 2篇 |
药学 | 13篇 |
中国医学 | 2篇 |
肿瘤学 | 2篇 |
出版年
2023年 | 1篇 |
2022年 | 4篇 |
2021年 | 16篇 |
2020年 | 7篇 |
2019年 | 4篇 |
2018年 | 11篇 |
2017年 | 9篇 |
2016年 | 10篇 |
2015年 | 12篇 |
2014年 | 16篇 |
2013年 | 11篇 |
2012年 | 15篇 |
2011年 | 10篇 |
2010年 | 12篇 |
2009年 | 7篇 |
2008年 | 11篇 |
2007年 | 12篇 |
2006年 | 7篇 |
2005年 | 6篇 |
2004年 | 8篇 |
2003年 | 6篇 |
2002年 | 10篇 |
2001年 | 2篇 |
1997年 | 1篇 |
1996年 | 1篇 |
1995年 | 1篇 |
1994年 | 1篇 |
1989年 | 1篇 |
排序方式: 共有212条查询结果,搜索用时 187 毫秒
1.
2.
3.
David K. Dosoo Kwaku P. Asante Kingsley Kayan Dennis Adu-Gyasi Kingsley Osei-Kwakye Emmanuel Mahama Samuel Danso Stephen Amenga-Etego Philip Bilson Kwadwo A. Koram Seth Owusu-Agyei 《The American journal of tropical medicine and hygiene》2014,90(4):767-773
Reference values derived from developed countries are used in many countries in Africa for interpretation of laboratory results obtained during routine healthcare and clinical trials. Use of locally derived reference values has been recommended. The purpose of the study was to establish age- and sex-specific reference values for children in the middle belt of Ghana. Reference values were determined for 21 biochemical and 18 hematologic parameters by using Clinical and Laboratory Standards Institute C28-A3 guidelines in a sample of 1,442 healthy children. Hemoglobin, hematocrit, mean cell volume, erythrocytes, urea, and creatinine were lower when compared with values from northern countries but alanine aminotransferase, aspartate aminotransferase, and total bilirubin were higher. A panel of locally relevant age- and sex-specific reference values was established for commonly used biochemical and hematologic tests in children in the middle part of Ghana. This will help in interpretation of laboratory results for clinical management of patients, screening, and safety monitoring during clinical trials. 相似文献
4.
Owusu-Agyei S Binka F Koram K Anto F Adjuik M Nkrumah F Smith T 《Tropical medicine & international health : TM & IH》2002,7(7):599-603
A cohort of 197 adults in Kassena-Nankana District (northern Ghana) was radically cured of malaria parasites to study subsequent incidence of malaria infection. During the following 20 weeks of the malaria transmission season, 49% experienced clinical attacks associated with Plasmodium falciparum parasitaemia. In a group of 202 adults identically followed-up 1 year later without being treated, only 38% experienced such episodes (log-rank test for equality of survivor functions, P=0.035). Clinical attacks in radically cured individuals presented with lower parasite densities but more symptoms. Randomized studies are needed to test the hypothesis that radical cure of P. falciparum enhances the risk and severity of subsequent clinical malaria attacks. 相似文献
5.
Kwadwo A. Yeboah Amy Allspaw Akram Al-Makki Brian M. Shepler 《Clinical therapeutics》2018,40(9):1592-1595
Purpose
Several antihypertensive medications have been associated with various forms of sexual dysfunction. We present a case report of a premenopausal patient with hydralazine-associated amenorrhea.Methods
The Naranjo adverse drug reaction probability scale was used to assess causality. We also performed a literature search on PubMed to find publications that report hydralazine-associated amenorrhea.Results
The Naranjo scale generated a score of 6, suggesting a probable relationship between amenorrhea and hydralazine therapy. No publications associating hydralazine with amenorrhea were identified.Implications
A probable relationship exists between hydralazine and the development of amenorrhea. 相似文献6.
Zachary Bauman Victor Coba Marika Gassner David Amponsah John Gallien Dionne Blyden Keith Killu 《Journal of Ultrasound》2015,18(4):343-348
Purpose
Point-of-care ultrasound evaluates inferior vena cava (IVC) and internal jugular vein (IJV) measurements to estimate intravascular volume status. The reliability of the IVC and IJV collapsibility index during increased thoracic or intra-abdominal pressure remains unclear.Methods
Three phases of sonographic scanning were performed: spontaneous breathing phase, increased thoracic pressure phase via positive pressure ventilation (PPV) phase, and increased intra-abdominal pressure (IAP) phase via laparoscopic insufflation to 15 mmHg. IVC measurements were done at 1–2 cm below the diaphragm and IJV measurements were done at the level of the cricoid cartilage during a complete respiratory cycle. Collapsibility index was calculated by (max diameter − min diameter)/max diameter × 100 %. Chi square, t test, correlation procedure (CORR) and Fisher’s exact analyses were completed.Results
A total of 144 scans of the IVC and IJV were completed in 16 patients who underwent laparoscopic surgery. Mean age was 46 ± 15 years, with 75 % female and 69 % African-American. IVC and IJV collapsibility correlated in the setting of spontaneous breathing (r2 = 0.86, p < 0.01). IVC collapsibility had no correlation with the IJV in the setting of PPV (r2 = 0.21, p = 0.52) or IAP (r2 = 0.26, p = 0.42). Maximal IVC diameter was significantly smaller during increased IAP (16.5 mm ± 4.9) compared to spontaneous breathing (20.6 mm ± 4.8, p = 0.04) and PPV (21.8 mm ± 5.6, p = 0.01).Conclusion
IJV and IVC collapsibility correlated during spontaneous breathing but there was no statistically significant correlation during increased thoracic or intra-abdominal pressure. Increased intra-abdominal pressure was associated with a significant smaller maximal IVC diameter and cautions the reliability of IVC diameter in clinical settings that are associated with intra-abdominal hypertension or abdominal compartment syndrome. 相似文献7.
Necessity of Keratinized Tissues for Dental Implants: A Clinical,Immunological, and Radiographic Study 下载免费PDF全文
8.
9.
Nancy O. Duah Neils B. Quashie Benjamin K. Abuaku Peter J. Sebeny Karl C. Kronmann Kwadwo A. Koram 《The American journal of tropical medicine and hygiene》2012,87(6):996-1003
In 2005, sulphadoxine-pyrimethamine (SP) became the drug of choice for intermittent preventive treatment of Plasmodium falciparum malaria in pregnancy (IPTp) in Ghana. Reports suggest the use of SP by others to treat uncomplicated malaria. Because of the increased use of SP, the prevalence of mutations in the genes, dihydrofolate reductase (dhfr), and dihydropteroate synthetase (dhps), linked to SP resistance in P. falciparum were determined. Blood samples from 945 children with uncomplicated malaria collected at nine sites from 2003 to 2010 were analyzed using polymerase chain reaction and restriction fragment length polymorphism. Prevalence of the dhfr triple and dhfr plus dhps quadruple mutations showed significant increase in trend from 2003 to 2010 (χ2 = 18.78, P < 0.001, χ2 = 15.11, P < 0.001, respectively). For dhps double mutant G437 + E540 the prevalence was low (1.12%) caused by the very low prevalence of E540. Our findings show the wide use of SP in Ghana and therefore its use for IPTp needs to be closely monitored. 相似文献
10.
Marilyne M. Lange MD PhD Joseph E. Martz MD Beverly Ramdeen Vicki Brooks Kwadwo Boachie-Adjei MPH Cornelis J. H. van de Velde MD PhD Warren E. Enker MD 《Annals of surgical oncology》2013,20(6):1806-1815