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排序方式: 共有201条查询结果,搜索用时 15 毫秒
1.
M Niewald W Lehmann B Scharding W Berberich K Schnabel H K Leetz 《Strahlentherapie und Onkologie》1986,162(7):448-454
A most precise immobilisation of the patient's head is indispensable in order to reach a high degree of exactness and reproducibility in radiotherapy of malignant head and neck tumors. Face masks made of different synthetic materials have proved to be a simple and economical solution for this problem. Based on our own experiences with "Baycast Longuettes" (manufacturing firm: Johnson & Johnson, Düsseldorf), eleven substances have been tested in the phantom (compound of plaster and synthetic resin, thermoplast, polyurethane foam, compounds of cotton and synthetic resin, and fibre glass compounds). An appropriate material was "Hexcelite" (manufacturing firm: Medimex, Hamburg), a reticulated thermoplast which after warming up can be easily adapted to the patient's face and which guarantees a very good fixation of the head. As compared to solid masks, there is only a slight superposition of the depth dose of Co-60 gamma radiation by secondary electrons from the mask material, so that an increased rate of radiogenic dermatitides is not to be expected. 相似文献
2.
Christof Ernst Berberich J r me Josse Fr d ric Laurent Tristan Ferry 《World journal of orthopedics》2021,12(3):119-128
In view of the demographic changes and projected increase of arthroplasty procedures worldwide, the number of prosthetic joint infection cases will naturally grow. Therefore, in order to counteract this trend more rigid rules and a stricter implementation of effective preventive strategies is of highest importance. In the absence of a "miracle weapon" priorities should lie in evidence-based measures including preoperative optimization of patients at higher infection risks, the fulfilment of strict hygiene rules in the operating theatre and an effective antibiotic prophylaxis regimen. Instead of a "one size fits all" philosophy, it has been proposed to adjust the antibiotic prophylaxis protocol to major infection risks taking into account important patient-and procedure-related risk factors. A stronger focus on the local application mode via use of high dose dual antibioticloaded bone cement in such risk situations may have its advantages and is easy to apply in the theatre. The more potent antimicrobial growth inhibition in vitro and the strong reduction of the prosthetic joint infection rate in risk for infection patients with aid of dual antibiotic-loaded bone cement in clinical studies align with this hypothesis. 相似文献
3.
A novel immunization method to induce cytotoxic T-lymphocyte responses (CTL) against plasmid-encoded herpes simplex virus type-1 glycoprotein D 总被引:2,自引:0,他引:2
Cruz PE Khalil PL Dryden TD Chiou HC Fink PS Berberich SJ Bigley NJ 《Vaccine》1999,17(9-10):1091-1099
DNA molecules complexed with an asialoglycoprotein-polycation conjugate, consisting of asialoorosomucoid (ASOR) coupled to poly-L-lysine, can enter hepatocytes which bear receptors for ASOR. We used this receptor-mediated DNA delivery system to deliver plasmid DNA encoding glycoprotein D (gD) of herpes simplex virus type 1 to ASOR-positive cells. Maximum expression of gD protein was seen at 3 days after injection of this preparation in approximately 13% of cells from BALB/c mice [hepatocytes from mice injected intravenously (i.v.) or peritoneal exudate cells from mice injected intraperitoneally (i.p.)]. In comparison with mice injected with either the plasmid vector alone or the gD-containing plasmid uncomplexed to ASOR, mice immunized with gD-containing plasmid complexed with ASOR-poly-L-lysine induced marked antigen-specific CTL responses. BALB/c mice immunized with gD-DNA developed a T-cell-mediated CTL response against target cells expressing gD and MHC class II glycoproteins, but not against cells expressing only gD and MHC class I molecules. In C3H mice, gD-DNA induced a T-cell-mediated CTL response against target cells expressing gD and class I MHC molecules. Serum anti-gD antibody in low titers were produced in both strains of mice. DNA complexed with ASOR-poly-L-lysine induced CTL responses in mice. 相似文献
4.
For many societies in the world onanism is taboo because of religious and medical ethics. From ancient times until the present day this type of body sensation is disclaimed by modern communities like a recurrent theme. After the discovery of the mechanism of fertilisation by the biologist Eduard van Beneden (1846-1910) in 1875 the feminine clitoris was declared to be a dispensable organ. The clitoris was suspected of causing hysteria, epilepsy and other forms of insanity. In the eighteenth century masturbation performed by young men was classified as a consumptive disease that caused inevitable death. The following presentation gives an historical overview through the history of onanism that demonstrates the artistic, philosophical and medical point of view on the sexuality of men. 相似文献
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6.
Berberich Anne Schmitt Lara-Marie Pusch Stefan Hielscher Thomas Rübmann Petra Hucke Nanina Latzer Pauline Heßling Bernd Lemke Dieter Kessler Tobias Platten Michael Wick Wolfgang 《Journal of neuro-oncology》2020,146(1):9-23
Journal of Neuro-Oncology - Anaplastic lymphoma kinase (ALK) is expressed in?~?60% of glioblastomas and conveys tumorigenic functions. Therefore, ALK inhibitory strategies with... 相似文献
7.
Bastian Christ Walther Glaubitt Katrin Berberich Tobias Weigel Jrn Probst Gerhard Sextl Sofia Dembski 《Materials》2022,15(8)
The development of novel fibrous biomaterials and further processing of medical devices is still challenging. For instance, titanium(IV) oxide is a well-established biocompatible material, and the synthesis of TiOx particles and coatings via the sol-gel process has frequently been published. However, synthesis protocols of sol-gel-derived TiOx fibers are hardly known. In this publication, the authors present a synthesis and fabrication of purely sol-gel-derived TiOx fiber fleeces starting from the liquid sol-gel precursor titanium ethylate (TEOT). Here, the α-hydroxy-carboxylic acid lactic acid (LA) was used as a chelating ligand to reduce the reactivity towards hydrolysis of TEOT enabling a spinnable sol. The resulting fibers were processed into a non-woven fleece, characterized with FTIR, 13C-MAS-NMR, XRD, and screened with regard to their stability in physiological solution. They revealed an unexpected dependency between the LA content and the dissolution behavior. Finally, in vitro cell culture experiments proved their potential suitability as an open-mesh structured scaffold material, even for challenging applications such as therapeutic medicinal products (ATMPs). 相似文献
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9.
Dr. med. H. J. Berberich 《Der Urologe. Ausg. A》2004,43(3):249-249
Ohne Zusammenfassung 相似文献
10.
Cell labelling with colloidal substances in whole blood 总被引:2,自引:1,他引:1
H. J. Schroth Prof. Dr. E. Oberhausen R. Berberich 《European journal of nuclear medicine and molecular imaging》1981,6(10):469-472
A method for the labelling of leucocytes with 99mTc-colloid is described. The labelling can be done in samples of whole blood, because the colloid is only taken up by the phagocytosing cells, the monocytes and the granulocytes. The part of the colloid that is not phagocytosed is brought to a soluble state with Na-citrate, so that only the phagocytosed colloid is reinjected. The labelling efficiency with this method is between 80% and 90%. Measurements of the activity in the leucocytes 3 h after reinjection, have shown that at least 50% of the labelled cells are at this time still available in the blood pool.The clinical results on 32 patients with the tentative diagnosis of an abdominal abscess and on 42 patients with the tentative diagnosis of septic loosening of an endoprosthesis have shown that the labelled leucocytes are very well suited to show up local foci of inflammation. 相似文献