全文获取类型
收费全文 | 1307篇 |
免费 | 86篇 |
国内免费 | 22篇 |
专业分类
耳鼻咽喉 | 5篇 |
儿科学 | 53篇 |
妇产科学 | 13篇 |
基础医学 | 172篇 |
口腔科学 | 23篇 |
临床医学 | 142篇 |
内科学 | 258篇 |
皮肤病学 | 23篇 |
神经病学 | 90篇 |
特种医学 | 271篇 |
外科学 | 114篇 |
综合类 | 15篇 |
预防医学 | 54篇 |
眼科学 | 12篇 |
药学 | 118篇 |
中国医学 | 4篇 |
肿瘤学 | 48篇 |
出版年
2022年 | 7篇 |
2021年 | 21篇 |
2020年 | 16篇 |
2019年 | 12篇 |
2018年 | 11篇 |
2017年 | 12篇 |
2016年 | 17篇 |
2015年 | 20篇 |
2014年 | 21篇 |
2013年 | 33篇 |
2012年 | 31篇 |
2011年 | 46篇 |
2010年 | 53篇 |
2009年 | 54篇 |
2008年 | 51篇 |
2007年 | 64篇 |
2006年 | 57篇 |
2005年 | 57篇 |
2004年 | 46篇 |
2003年 | 45篇 |
2002年 | 46篇 |
2001年 | 43篇 |
2000年 | 22篇 |
1999年 | 25篇 |
1998年 | 43篇 |
1997年 | 47篇 |
1996年 | 33篇 |
1995年 | 35篇 |
1994年 | 14篇 |
1993年 | 22篇 |
1992年 | 21篇 |
1991年 | 30篇 |
1990年 | 23篇 |
1989年 | 33篇 |
1988年 | 23篇 |
1987年 | 26篇 |
1986年 | 23篇 |
1985年 | 23篇 |
1984年 | 20篇 |
1983年 | 12篇 |
1982年 | 24篇 |
1981年 | 15篇 |
1980年 | 14篇 |
1979年 | 13篇 |
1978年 | 17篇 |
1977年 | 15篇 |
1976年 | 11篇 |
1975年 | 9篇 |
1973年 | 8篇 |
1970年 | 7篇 |
排序方式: 共有1415条查询结果,搜索用时 15 毫秒
1.
2.
3.
4.
Dr. J.-T. Gräsner M. Fischer K. H. Altemeyer J. Bahr B. W. Böttiger V. Dörges R. Franz A. Gries H. Krieter M. Messelken T. Rosolski M. Ruppert T. Schlechtriemen J. Scholz J. Schüttler B. Wolke J. F. Zander 《Notfall & Rettungsmedizin》2005,8(2):112-115
Within the scope of the symposium “Rescue Medicine in Germany” (held at the Reisensburg near Ulm in 2002), the need for a standardized data acquisition set for prehospital cardiac arrest patients was identified. Therefore, the working group “Emergency Medicine” of the German Society of Anesthesiology and Intensive Care Medicine (DGAI) created a nationwide data acquisition system for primary medical care in prehospital cardiac arrest patients treated with cardiopulmonary resuscitation procedures. The system is in full accordance with the “Utstein style.” Integration of this data acquisition system, for example into the “Dortmund protocol,” is providing a standardized data web base of all acquired prehospital data analyze and to compare processing and structural quality. As additional modules for this nationwide data web base system, an inhospital module “further clinical treatment” and a “long-term follow-up” module are currently in the developmental process. 相似文献
5.
6.
Roald Bahr Fernando Pena Joe Shine William D. Lew Conrad Lindquist Stein Tyrdal Lars Engebretsen 《Acta orthopaedica》1997,68(5):435-441
We analyzed the changes in lateral ligament forces during anterior drawer and talar tilt testing and examined ankle joint motion during testing, following an isolated lesion of the anterior talofibular ligament (ATFL) or a combined lesion of the ATFL and calcaneofibular ligament (CFL). 8 cadaver specimens were held in a specially designed testing apparatus in which the ankle position (dorsiflexion-plantarflexion and supination-pronation) could be varied in a controlled manner. Ligament forces were measured with buckle transducers, and joint motion was measured with an instrumented spatial linkage. An anterior drawer test was performed using an 80 N anterior translating force, and a talar tilt test was performed using a 5.7 Nm supination torque with intact ligaments, after sectioning of the ATFL, and again after sectioning of the CFL. The tests were repeated at 10° dorsiflexion, neutral, and 10° and 20° plantarflexion. In the intact ankle, the largest increases in ATFL force were observed during testing in plantarflexion, whereas the largest increases in CFL force were observed in dorsiflexion. Isolated ATFL injury caused only small laxity changes, but a pronounced increase in laxity was observed after a combined CFL and ATFL injury. 相似文献
7.
Kinnison ML; Perler BA; Kaufman SL; Mitchell SE; Kadir S; Williams GM; White RI Jr 《Radiology》1986,160(3):727-730
In situ saphenous vein grafts are being used with increasing frequency for bypass procedures involving the femoral and popliteal arteries. Complications of these procedures include anastomotic stenoses and persistent arteriovenous fistulae that may result in failure of the graft. Balloon angioplasty and embolotherapy with detachable balloons were employed successfully in three or four recent cases of patients with complications from in situ grafts. Tailored angiography is essential for evaluating in situ grafts, and interventional techniques are extremely useful for managing complications. 相似文献
8.
Idziorek Khalife Billaut-Mulot Hermann Aumercier Mouton Capron Bahr 《Clinical and experimental immunology》1998,112(1):84-91
The chemoattractant cytokine IL-16 has been reported to suppress lymphocyte activation and to inhibit HIV-1 replication in acutely infected T cells. We have cloned and expressed human IL-16 in Escherichia coli and investigated whether the recombinant protein could regulate the level of lymphocyte apoptosis from HIV-1-infected subjects. After purification and refolding, only 2–10% of the recombinant cytokine was present in a biologically active homotetrameric form. This could explain the need for high concentrations of the bacterially derived IL-16 to induce significant inhibition of HIV-1 replication. Addition of IL-16 to unstimulated peripheral blood mononuclear cell (PBMC) cultures from HIV-1-infected subjects did not modify the observed level of spontaneous lymphocyte apoptosis. In contrast, IL-16 added to PBMC cultures stimulated with anti-CD3, anti-CD95 or dexamethasone reduced significantly the percentage of lymphocytes undergoing AICD. This effect was found to correlate with the ability of the cytokine to decrease CD95 expression on activated CD4+ T cells. Comparative studies on PBMC from healthy individuals indicated that the regulation of apoptosis levels by IL-16 is a complex phenomenon and could depend on the nature of the activator used and/or the immune status of lymphocytes tested. The outcome of CD4 cross-linking on T cells by various ligands is discussed in the context of the observed beneficial activities of IL-16 and its potential role in the treatment of HIV disease. 相似文献
9.
T. Hansson C. von Bahr M. Marklund J.-O. Svensson M. Ingelman-Sundberg J. Lundstrm 《Basic & clinical pharmacology & toxicology》1992,71(6):416-419
Abstract: Incubation of the tricyclic antidepressant desmethylimpramine (DMI) with rat liver or brain microsomes in the presence of NADPH or t-butyl-hydroperoxide (TBH) revealed different regiospecificities in the hydroxylation reactions between the tissues. In brain preparations 10-OH-DMI was formed in reactions supported by NADPH or TBH, whereas in the latter case also an unidentified metabolite could be detected. Inclusion of exogenous NADPH-cytochrome P450 reductase in the brain preparations caused a 10-fold higher rate of 10-hydroxylation but no 2-OH-DMI could be detected. By contrast, liver microsomal preparations in the presence of NADPH catalyzed formation of both 2- and 10-OH-DMI, whereas only 10-OH-DMI was formed in TBH-supported reactions. The results indicate that antidepressant drugs can be metabolized in brain with different stereospecificity as compared to liver. 相似文献
10.
Dr. rer. biol. hum. Dipl.-Soz. J. Bahr 《Notfall & Rettungsmedizin》2007,10(3):197-200
To bridge the time gap without therapeutic intervention until the EMS team arrives, lay rescuers should be trained in performing adequate cardiopulmonary resuscitation (CPR). About 2 million people attend CPR courses each year in Germany. However, it has been observed that the skills acquired by the attendees already begin to deteriorate shortly thereafter. As an alternative, efforts are currently underway to assess telephone-guided resuscitation performed by bystanders on site following instruction received via telephone. Use of automated external defibrillators by helpers first on the scene is considered to be another option. Initial experience has shown, however, that little use is made of the equipment located at heavily frequented areas (airports, railroad stations, etc.). At these locations it seems to make more sense to train the first responders (police force, fire department). Further measures need to be implemented to improve the actual assistance rendered in terms of quality and quantity. 相似文献