全文获取类型
收费全文 | 730篇 |
免费 | 28篇 |
国内免费 | 22篇 |
专业分类
耳鼻咽喉 | 1篇 |
儿科学 | 130篇 |
基础医学 | 100篇 |
口腔科学 | 44篇 |
临床医学 | 109篇 |
内科学 | 152篇 |
皮肤病学 | 14篇 |
神经病学 | 8篇 |
特种医学 | 106篇 |
外科学 | 31篇 |
综合类 | 7篇 |
预防医学 | 34篇 |
药学 | 32篇 |
肿瘤学 | 12篇 |
出版年
2017年 | 6篇 |
2014年 | 11篇 |
2013年 | 20篇 |
2012年 | 6篇 |
2011年 | 15篇 |
2010年 | 29篇 |
2009年 | 18篇 |
2008年 | 7篇 |
2007年 | 23篇 |
2006年 | 8篇 |
2005年 | 8篇 |
2001年 | 8篇 |
2000年 | 5篇 |
1999年 | 16篇 |
1998年 | 41篇 |
1997年 | 46篇 |
1996年 | 40篇 |
1995年 | 19篇 |
1994年 | 27篇 |
1993年 | 21篇 |
1992年 | 18篇 |
1991年 | 12篇 |
1990年 | 13篇 |
1989年 | 14篇 |
1988年 | 35篇 |
1987年 | 24篇 |
1986年 | 21篇 |
1985年 | 16篇 |
1984年 | 26篇 |
1983年 | 16篇 |
1982年 | 20篇 |
1981年 | 20篇 |
1980年 | 16篇 |
1979年 | 11篇 |
1978年 | 7篇 |
1977年 | 5篇 |
1976年 | 7篇 |
1975年 | 10篇 |
1973年 | 4篇 |
1972年 | 8篇 |
1971年 | 13篇 |
1970年 | 8篇 |
1968年 | 4篇 |
1967年 | 4篇 |
1966年 | 6篇 |
1964年 | 4篇 |
1963年 | 5篇 |
1962年 | 5篇 |
1960年 | 6篇 |
1954年 | 4篇 |
排序方式: 共有780条查询结果,搜索用时 16 毫秒
1.
Factors influencing women to undergo screening mammography 总被引:2,自引:0,他引:2
2.
Braffman BH; Coleman BG; Ramchandani P; Arger PH; Nodine CF; Dinsmore BJ; Louie A; Betsch SE 《Radiology》1994,190(3):797
3.
4.
Rupture of the distal biceps tendon: evaluation with MR imaging 总被引:2,自引:0,他引:2
5.
Seven middle-aged men with manifest type II diabetes mellitus underwent an endurance training programme for 10–15 weeks. The maximal aerobic capacity, as well as the endurance capacity, was improved by 10% (p<0.05). The intramuscular glycogen store increased by more than 80% (p<0.05) from 350 μmol/g dw (dry weight), and the activities of citrate synthase and 3-hydroxy-acyl-CoA dehydrogenase increased by more than 50% (p<0.05) and 30% (p<0.05). The activity of glycogen synthase was decreased by approximately 20% (p<0.05), whereas lactate dehydrogenase remained unchanged. Capillaries/fibre and fibre area increased by more than 50% (p<0.05) and 30% (p<0.05) leaving the area of supply constant. Training did not influence fasting blood lipids and glucose, glycosylated hemoglobin, oral glucose tolerance, and insulin response to an oral glucose load measured 72 hours post-exercise. It is concluded that patients with manifest type II diabetes, as normoglycaemic individuals, adapt to physical training. However, no persistent effect on glucohomeostasis and lipaemia is produced by short-term training in the diabetic patients. 相似文献
6.
Evaluation of an Educational Programme for Telephone Advisers in Primary Health Care 总被引:1,自引:0,他引:1
Marklund B, Silfverhielm B and Bengtsson C. Evaluation of aneducational programme for telephone advisers in primary healthcare. Family Practice 1989; 6: 263267. Telephone advisers, usually registered nurses, have a very importantrole in the Swedish primary health care service. In order toimprove this service, a special educational programme has beenworked out for registered nurses working at a Swedish healthcentre. The purpose of this paper is to evaluate this educationalprogramme at one of the health centres. The quality of the telephoneadvice was evaluated by a blind observer. After the educationalprogramme the quality of advice was improved. Among the participatingnurses, the confidence and the satisfaction with the work increasedafter the educational programme. 相似文献
7.
Androgen receptor YAC transgenic mice carrying CAG 45 alleles show trinucleotide repeat instability 总被引:1,自引:15,他引:1
La Spada AR; Peterson KR; Meadows SA; McClain ME; Jeng G; Chmelar RS; Haugen HA; Chen K; Singer MJ; Moore D; Trask BJ; Fischbeck KH; Clegg CH; McKnight GS 《Human molecular genetics》1998,7(6):959-967
X-linked spinal and bulbar muscular atrophy (SBMA) is caused by a CAG
repeat expansion in the first exon of the androgen receptor (AR) gene.
Disease-associated alleles (37-66 CAGs) change in length when transmitted
from parents to offspring, with a significantly greater tendency to shift
size when inherited paternally. As transgenic mice carrying human AR cDNAs
with 45 and 66 CAG repeats do not display repeat instability, we attempted
to model trinucleotide repeat instability by generating transgenic mice
with yeast artificial chromosomes (YACs) carrying AR CAG repeat expansions
in their genomic context. Studies of independent lines of AR YAC transgenic
mice with CAG 45 alleles reveal intergenerational instability at an overall
rate of approximately 10%. We also find that the 45 CAG repeat tracts are
significantly more unstable with maternal transmission and as the
transmitting mother ages. Of all the CAG/CTG repeat transgenic mice
produced to date the AR YAC CAG 45 mice are unstable with the smallest
trinucleotide repeat mutations, suggesting that the length threshold for
repeat instability in the mouse may be lowered by including the appropriate
flanking human DNA sequences. By sequence-tagged site content analysis and
long range mapping we determined that one unstable transgenic line has
integrated an approximately 70 kb segment of the AR locus due to
fragmentation of the AR YAC. Identification of the cis - acting elements
that permit CAG tract instability and the trans -acting factors that
modulate repeat instability in the AR YAC CAG 45 mice may provide insights
into the molecular basis of trinucleotide repeat instability in humans.
相似文献
8.
9.
10.
It is well recognized that the ability to cryopreserve unfertilizedhuman oocytes would make a significant contribution to infertilitytreatment. However, despite considerable interest, very fewsuccessful pregnancies have arisen from cryopreserved oocytesafter thawing, insemination and transfer of the subsequent embryo.The reasons for this lack of progress may well result from adearth of information on how the various biophysical changesduring a cryopreservation regimen affect human oocyte function.Recently, fundamental studies on the effects of cooling, membranepermeability, cryoprotectant addition and ice formation havebeen performed on human oocytes by a number of groups, and theseform the basis of the current review. It is likely that successfulhuman oocyte cryopreservation will only follow once these factorsare fully understood, but the existing base of knowledge shouldprovide a platform for further improvements in the techniquescurrently employed. 相似文献