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排序方式: 共有572条查询结果,搜索用时 15 毫秒
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G A Golubiatnikova T V Koroleva V I Kalmykova V F Nastenko E S Markova 《Terapevticheski? arkhiv》1988,60(8):98-102
A comprehensive study of blood lipid composition and microcirculatory indices was performed in 88 patients with diabetes mellitus (DM) combined with coronary heart disease (CHD). A "syndrome" of mutual aggravation was shown to develop in the combination of DM and CHD. As a result of it the above indices were changed depending on clinical signs of each of the two diseases. Lipid metabolic and microcirculatory derangements depended mostly on a degree of compensation of carbohydrate metabolism. a DM type, the presence of diabetic angiopathies and CHD gravity. 相似文献
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Recurrent NAB2–STAT6 gene fusions and oestrogen receptor‐α expression in pulmonary adenofibromas
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Nicola Fusco Elena Guerini‐Rocco Claudia Augello Andrea Terrasi Giulia Ercoli Caterina Fumagalli Davide Vacirca Paola Braidotti Antonina Parafioriti Marta Jaconi Letterio Runza Vijayalakshmi Ananthanarayanan Fabio Pagni Silvano Bosari Massimo Barberis Stefano Ferrero 《Histopathology》2017,70(6):906-917
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Roberta Cocchiara Giovanna Di Trapani Antonina Azzolina Domenico Geraci 《Journal of immunoassay & immunochemistry》2013,34(4):337-352
Abstract An ELISA assay is described for the measurement of the smIgG. The method is based on the detection of cell-smIgG directly on the same microplate used for the culture. The cells, preincubated at 37°C for one hour, were cultured in the presence of S-ConA and serum-free medium for two days. Using this strategy, the background noise due to non specific adsorbtion of IgG to plastic wells and cytophilic antibodies was eliminated. The cells in the presence of S-ConA and serum-free medium adhered to the plastic wells, and the cell-smIgG were detected using an anti-human IgG covalently linked to alkaline phosphatase or its F(ab')2 fragment. The possibility of measuring the modulation of the expression of the cell-smIgG without any additional manipulation is stressed. 相似文献
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Chuck Ramirez Antonina M. Lee Ken Welch 《Journal of the Association for Vascular Access》2012,17(4):210-213
BackgroundCentral line-associated blood stream infection (CLABSI) rates in adult care intensive care units have been decreasing across the board. However, we continued to see just a few infections in patients whose catheters are in for >4 days. Therefore, we looked at infections associated with intraluminal contamination to help reduce our infection rate.MethodsA protective cap trial was developed and implemented in 2 intensive care units. All of the central venous catheter and intravenous tubing access valves were covered with a protective cap saturated with alcohol. This intervention eliminated the need to wipe off intravenous access points with an alcohol swab. The study was done as a nonrandomized prospective trial occurring March 1, 2011 through February 29, 2012.ResultsDuring 2010, there were 4 CLABSI-related infections. By the end of the trial, we had incurred 1 catheter-associated blood stream infection. CLABSI rate reduced from 1.9 in 2010 to 0.5 during the 1-year trial period.ConclusionsThe implementation of the port protector cap system resulted in lower infection rates compared with an alcohol swab technique. Our results indicate that consistent use of the caps in tandem with strict compliance does influence CLABSI rates. 相似文献
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Simonetta Genovesi Laura Antolini Antonina Orlando Sujit Brahmochary Alessandra De Servi Silvia Capelli 《International journal of food sciences and nutrition》2017,68(4):467-472
The influence of feeding patterns on the growth of infants and how salt is included in the diet are unknown in the area of West Bengal, India. A cross-sectional study was carried on 517 infants (median age 6.5 months). Negative Z-scores were observed for all anthropometric parameters. About 72.7% of infants aged 0–6 months received exclusive breastfeeding. In the 6–12-month-old group (n?=?235), 91.5% had salt added to foods. In a regression model adjusted for age, a low salt diet resulted a significant factor in increasing weight-for-length and BMI for age z-scores, with increments equal to 0.637 SD (p?=?0.037) and 0.650 SD (p?=?0.036), respectively.In West Bengal infants showing poor growth, breastfeeding was associated with better anthropometric indexes, but early in life salt is added to their diet. Early life low weight coupled with high salt intake may be a risk factor for arterial hypertension in Indian children. 相似文献
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Isidro Machado Beatriz Llombart Julia Cruz Víctor Traves Celia Requena Eduardo Nagore Antonina Parafioriti Carlos Monteagudo Antonio Llombart‐Bosch 《Journal of cutaneous pathology》2017,44(7):632-638
Desmoplastic melanoma (DM) and cutaneous malignant peripheral nerve sheath tumors (MPNST) reveal histological and immunohistochemical similarities, including S100 positivity and negative staining for conventional melanocytic markers. We present 3 cases of cutaneous S100‐positive spindle cell tumors in elderly patients, in which first findings led to initial misdiagnoses as cutaneous MPNST and benign peripheral sheath nerve tumor (neurofibroma). The identification of adjacent atypical melanocytic hyperplasia in the overlying skin along with tumor cell proliferation, also in the superficial dermis, the neurotropic component and the absence of any relationship between the tumor and a major nerve, pre‐existing neural benign tumor or the existence of stigmata suggestive of neurofibromatosis raised consideration of a DM. Careful attention should be paid to the presence of a firm dermal nodule and atypical scar lesions especially in sun‐exposed areas (mainly head and neck region) in elderly patients associated with S100‐positive spindle cell proliferation, solar elastosis and adjacent atypical melanocytic proliferation. In such cases, the possibility of a DM should be excluded with caution, especially if the tumor reveals a paucicellular morphology resembling various non‐melanocytic neoplasms including malignant or benign peripheral sheath nerve tumors. 相似文献
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A. A. Isengulova Z. A. Kalmykova I. V. Miroshnichenko 《Bulletin of experimental biology and medicine》2009,147(4):390-393
The relationship between the process of ethanol preference formation in rat pups periodically separated from mothers during
the first half of the nest period and the intensity of maternal behavior of females was studied. The progeny of females with
poor maternal behavior and/or separated from mothers is characterized by slow somatic development and high level of ethanol
consumption. The quality of maternal care was inessential for the formation of ethanol preference in rats separated from mothers. 相似文献