全文获取类型
收费全文 | 10838篇 |
免费 | 558篇 |
国内免费 | 31篇 |
专业分类
耳鼻咽喉 | 173篇 |
儿科学 | 349篇 |
妇产科学 | 423篇 |
基础医学 | 1407篇 |
口腔科学 | 146篇 |
临床医学 | 824篇 |
内科学 | 2849篇 |
皮肤病学 | 165篇 |
神经病学 | 1017篇 |
特种医学 | 252篇 |
外科学 | 1525篇 |
综合类 | 33篇 |
一般理论 | 2篇 |
预防医学 | 750篇 |
眼科学 | 171篇 |
药学 | 676篇 |
中国医学 | 37篇 |
肿瘤学 | 628篇 |
出版年
2023年 | 38篇 |
2022年 | 91篇 |
2021年 | 180篇 |
2020年 | 101篇 |
2019年 | 192篇 |
2018年 | 240篇 |
2017年 | 168篇 |
2016年 | 150篇 |
2015年 | 227篇 |
2014年 | 321篇 |
2013年 | 376篇 |
2012年 | 581篇 |
2011年 | 609篇 |
2010年 | 355篇 |
2009年 | 288篇 |
2008年 | 600篇 |
2007年 | 656篇 |
2006年 | 666篇 |
2005年 | 600篇 |
2004年 | 596篇 |
2003年 | 542篇 |
2002年 | 554篇 |
2001年 | 364篇 |
2000年 | 391篇 |
1999年 | 306篇 |
1998年 | 108篇 |
1997年 | 92篇 |
1996年 | 91篇 |
1995年 | 87篇 |
1994年 | 70篇 |
1993年 | 74篇 |
1992年 | 194篇 |
1991年 | 182篇 |
1990年 | 148篇 |
1989年 | 123篇 |
1988年 | 122篇 |
1987年 | 120篇 |
1986年 | 84篇 |
1985年 | 79篇 |
1984年 | 60篇 |
1983年 | 43篇 |
1982年 | 39篇 |
1981年 | 35篇 |
1979年 | 36篇 |
1978年 | 24篇 |
1973年 | 26篇 |
1970年 | 34篇 |
1969年 | 23篇 |
1968年 | 37篇 |
1967年 | 25篇 |
排序方式: 共有10000条查询结果,搜索用时 15 毫秒
1.
2.
3.
José Luis R Martin Víctor Pérez Montse Sacristán Fernando Rodríguez-Artalejo Cristóbal Martínez Enric Alvarez 《European psychiatry》2006,21(1):11-20
OBJECTIVE: To assess antipsychotic medication in the treatment of schizophrenia, based on trial drop-out rates. METHOD: The studies included were randomised controlled trials that compared any of the four clinically best-established atypical antipsychotics (quetiapine, olanzapine, risperidone or clozapine) against either of two typical antipsychotics regarded as the gold standard (haloperidol or chlorpromazine). RESULTS: Meta-analysis indicated less risk of all-cause patient withdrawal from atypical medication trials where dosage was flexible, in both the short, relative risk (RR) 0.70 (95% CI 0.64-0.76), P<0.00001, and long term, RR 0.72 (0.65-0.80), P<0.00001. Similar results were observed for withdrawal due to adverse events, RR: 0.54 (0.41-0.72), P<0.0001. Nevertheless, the favourable effects of atypical medication disappeared in trials relying on fixed dosage. CONCLUSIONS: We detected a significant positive effect in terms of the outcome of treatment discontinuation for atypical versus typical medication, though only where the use of flexible rather than fixed doses (closer to an experimental control situation) was possible. 相似文献
4.
Computed tomographic (CT) scans of the brain in a child with Smith-Lemli-Opitz syndrome revealed enlargement of the ventricular system, hypoplasia of the cerebellum, and abnormal thickening of the gray matter, consistent with pachygyria. These findings have been previously noted in autopsies performed on patients with this disorder. We conclude that CT scanning is a valuable tool in the evaluation of children suspected of having the Smith-Lemli-Opitz syndrome. 相似文献
5.
Tim Wagner Jarrett Rushmore Antoni Valero-Cabre 《Cortex; a journal devoted to the study of the nervous system and behavior》2009,45(9):1025-137
Transcranial Magnetic Stimulation (TMS) induces electrical currents in the brain to stimulate neural tissue. This article reviews our present understanding of TMS methodology, focusing on its biophysical foundations. We concentrate on how the laws of electromagnetic induction apply to TMS; addressing issues such as the location, area (i.e., focality), depth, and mechanism of TMS. We also present a review of the present limitations and future potential of the technique. 相似文献
6.
7.
Laura Cisneros Maria-Carlota Londo?o Carmen Blasco Ramón Bataller Rosa Miquel Miquel Bruguera Pere Ginès Antoni Rimola 《Liver transplantation》2007,13(7):1017-1027
The pathogenic mechanisms of accelerated graft fibrosis in hepatitis C recurrence after liver transplantation (LT) are not well established. The aim of the study was to assess whether a greater activation of hepatic stellate cells (HSC), the major collagen-producing cells in the liver, can occur in these patients as compared to non-LT patients with chronic hepatitis C. We determined the amount of activated HSC by computer-based morphometric analysis of alpha-smooth muscle actin (alphaSMA)-positive cells and the hepatic TGFbeta(1) expression by immunohistochemistry in 46 LT patients with hepatitis C recurrence, 35 non-LT patients with chronic hepatitis C, and 16 controls. Hepatic alphaSMA and TGFbeta(1) expression was higher in LT patients with hepatitis C recurrence than in controls and was correlated with fibrosis stage and progression rate. No significant difference in alphaSMA and TGFbeta(1) expression was observed between LT and non-LT patients with hepatitis C, with the exception of a higher transforming growth factor beta-1 (TGFbeta(1)) expression in non-LT patients in the early stages of fibrosis. LT patients receiving cyclosporine (CsA) or tacrolimus (FK) had a similar fibrosis progression rate and alphaSMA and TGFbeta(1) expression. In conclusion, the accelerated fibrosis observed in LT patients with hepatitis C recurrence does not seem to be related to a greater amount of activated HSC and TGFbeta(1) expression in the grafts of these patients as compared to non-LT patients with chronic hepatitis C. In LT patients, the amount of activated HSC and TGFbeta(1) expression correlated with fibrosis stage and progression, without any apparent influence of the type of calcineurin inhibitor administered. 相似文献
8.
9.
10.
Localization of epileptogenic foci using a simple reference-subtraction montage to document small interchannel time differences 总被引:1,自引:0,他引:1
P Jayakar M S Duchowny T J Resnick L A Alvarez 《Journal of clinical neurophysiology》1991,8(2):212-215
We present a modified EEG montage that detects small interchannel time differences and assists in localizing the epileptogenic focus. Regions with apparently synchronous epileptic discharges are displayed simultaneously in referential and subtraction derivations. The subtraction derivation is a bipolar configuration of two regions of interest that are not necessarily adjacent. The referential derivation reveals the polarity, voltage, and morphology of the two discharges, and the subtraction derivation detects asynchrony; the combined reference-subtraction derivation thus indicates the region that is activated first. 相似文献