全文获取类型
收费全文 | 4426篇 |
免费 | 257篇 |
国内免费 | 34篇 |
专业分类
耳鼻咽喉 | 30篇 |
儿科学 | 127篇 |
妇产科学 | 116篇 |
基础医学 | 653篇 |
口腔科学 | 126篇 |
临床医学 | 326篇 |
内科学 | 1090篇 |
皮肤病学 | 183篇 |
神经病学 | 468篇 |
特种医学 | 160篇 |
外科学 | 424篇 |
综合类 | 7篇 |
一般理论 | 1篇 |
预防医学 | 232篇 |
眼科学 | 23篇 |
药学 | 343篇 |
中国医学 | 14篇 |
肿瘤学 | 394篇 |
出版年
2023年 | 50篇 |
2022年 | 86篇 |
2021年 | 156篇 |
2020年 | 106篇 |
2019年 | 154篇 |
2018年 | 142篇 |
2017年 | 108篇 |
2016年 | 107篇 |
2015年 | 145篇 |
2014年 | 184篇 |
2013年 | 208篇 |
2012年 | 324篇 |
2011年 | 347篇 |
2010年 | 179篇 |
2009年 | 205篇 |
2008年 | 278篇 |
2007年 | 251篇 |
2006年 | 250篇 |
2005年 | 239篇 |
2004年 | 215篇 |
2003年 | 178篇 |
2002年 | 139篇 |
2001年 | 65篇 |
2000年 | 49篇 |
1999年 | 52篇 |
1998年 | 28篇 |
1997年 | 24篇 |
1996年 | 28篇 |
1995年 | 21篇 |
1994年 | 21篇 |
1993年 | 22篇 |
1992年 | 33篇 |
1991年 | 31篇 |
1990年 | 37篇 |
1989年 | 28篇 |
1988年 | 34篇 |
1987年 | 22篇 |
1986年 | 29篇 |
1985年 | 16篇 |
1984年 | 6篇 |
1983年 | 11篇 |
1982年 | 7篇 |
1981年 | 6篇 |
1980年 | 11篇 |
1979年 | 15篇 |
1978年 | 7篇 |
1976年 | 9篇 |
1972年 | 5篇 |
1971年 | 5篇 |
1967年 | 6篇 |
排序方式: 共有4717条查询结果,搜索用时 15 毫秒
1.
2.
3.
Marco Cirillo Andrea Amaducci Emmanuel Villa Margherita Dalla Tomba Federico Brunelli Zen Mhagna Giovanni Troise Eugenio Quaini 《Journal of cardiothoracic surgery》2006,1(1):40-11
Background
Long-term morphofunctional outcome may vary widely in surgical anterior left ventricular wall restoration, suggesting variability in post-surgical remodeling similar to that observed following acute myocardial infarction. The aim of this pilot study was to demonstrate that surgical restoration obtained with a particular shape of endoventricular patch leads to steady morphofunctional ventricular improvement when geometry, volume and residual akinesia can be restored as normal as possible. 相似文献4.
5.
M Lacher K Schneider R Dalla Pozza D V Schweinitz 《Zeitschrift für Kinderchirurgie》2007,17(5):362-364
Prostaglandin E1 (PGE1) is widely used in neonates with cyanotic congenital heart disease who depend on the patency of the ductus arteriosus for oxygenation. Side effects of prostaglandin therapy are common and include respiratory depression, generalized flushing, and cardiovascular and neurological effects. Little is known about the complex effects on the gastrointestinal tract. We report on an infant with gastric outlet obstruction after long-term prostaglandin administration. At the age of 1 month, feeding problems developed with projectile vomiting. Ultrasonography showed progressive elongation of the antropyloric channel without wall thickening, which was causing gastric outlet obstruction. Three days after cardiac surgery and cessation of prostaglandin therapy, the infant fed normally and rapidly gained weight. The clinical signs in such patients can mimic hypertrophic pyloric stenosis. Therefore, the sonographic findings should not be confused with pyloric wall thickening to avoid a false diagnosis and unnecessary surgery. The symptoms diminish with cessation of the prostaglandin therapy after a corrective cardiac operation. 相似文献
6.
7.
Marina Quartu Maria Pina Serra Annalisa Manca Paolo Follesa Rossano Ambu Marina Del Fiacco 《International journal of developmental neuroscience》2003,21(6):309-320
The immunohistochemical occurrence of the high affinity neurotrophin (NT) receptors trkA, trkB, and trkC is shown in the pre-term newborn, infant, and adult human post-mortem cerebellum. Immunoreactive neuronal perikarya and processes were observed in all specimens examined, where they appeared unevenly distributed in the cerebellar cortical layers and deep nuclei, and showed regional differences among cerebellar lobules and folia. The trk receptor-antibodies, tested by Western blot on human cerebellum homogenates, revealed multiple immunoreactive bands for trkA and single bands for trkB and trkC. The results obtained show the tissue localization of the trk receptor-like immunoreactivity in the human cerebellum from prenatal to adult age. The analysis for codistribution of the receptors with the relevant ligand and among the receptors in discrete cortical and deep nuclei tissue fields shows a wide variety of conditions, from a good similarity in terms of type and density of labeled structures, to a lack of correspondence, and suggests the possibility of colocalization of trk receptors with the relevant neurotrophin and among them in the cerebellar cortex. These results sustain the concept that the neurotrophin trophic system participates in the development, differentiation, and maintenance of the human cerebellar connectivity and support the possibility of a multifactorial trophic support for the neurotrophins through target-derived and local mechanisms. 相似文献
8.
Annalisa Volpi Francesco Bacci Angelo Paradiso Luca Saragoni Emanuela Scarpi Monica Ricci Mirella Aldi Simonetta Bianchi Pietro Muretto Fiorella Nuzzo Gianni Simone Anita Mangia Francesco Schittulli Dino Amadori 《Modern pathology》2004,17(9):1038-1044
Available results highlight the lack of good level of evidence studies on the pure prognostic value of histological grade. In the present study, the prognostic relevance of histological grade and of its three components, tubule formation, nuclear pleomorphism and mitotic count, was analyzed in a series of 372 patients with node-negative breast cancer treated with locoregional therapy alone until early relapse. Histological grade was determined blindly by two observers and discordance between evaluations was resolved after joint review using a multihead microscope. No relation was observed between histological grade and any of its three components and disease-free survival. Conversely, a significant relation was observed between histological grade and distant metastasis-free survival (at 6 years, 94, 86 and 76% for grades 1, 2 and 3, respectively, P=0.013) as well as overall survival (98, 90 and 86%, P=0.001). A breakdown analysis as a function of the three components showed that neither tubule formation nor nuclear pleomorphism was associated with prognosis, and only mitotic count strongly influenced both distant metastasis-free survival (91, 82 and 74%, P=0.014) and overall survival (97, 87 and 85%, P=0.011). Histological grade suffers from a much higher subjectivity than any other microscopic evaluation of biomarkers as it is the sum of three different morphological features. Within the Italian Network for Quality Assessment of Tumor Biomarkers program we observed that histological grade is an independent prognostic variable, but also that this role is ascribable only to the number of mitotic figures. In conclusion, due to the ever smaller size of diagnosed breast cancers, resulting in less cancer tissue for biofunctional and molecular analysis, mitotic count evaluated under strict quality control conditions seems to be an accurate and feasible prognostic variable. 相似文献
9.
R S Pozzi Mucelli G Muner F Pozzi Mucelli M Pozzi Mucelli F Marotti L Dalla Palma 《European journal of radiology》1986,6(3):168-177
Acetabular fractures represent a complex variety that are classified in different types. Conventional radiology is often inadequate to demonstrate and classify the fractures. Computed tomography (CT) has already been shown to be superior in this field. A further advantage of CT is represented by the recent availability of three-dimensional (3D) images that are realized from axial CT scans by means of a new software. The Authors report the applications of this new software to the study of the normal acetabulum and in patients with fractures. 3D images allows an effective demonstration of the fracture, its irradiation and the dislocation of bone fragments. The information is contained in one or few images rather than many axial images. Therefore the role of 3D images may be considered complementary to axial CT scans. 相似文献
10.
Partial seizures and migraine 总被引:1,自引:0,他引:1
D Mancia G C Manzoni M G Terzano G Pavesi M Marchini B Dalla Bernardina 《Functional neurology》1986,1(4):439-453
Epilepsy and migraine, despite some common features, have quite different pathophysiological mechanisms. Studies carried out on large population samples have shown that the relationships between migraine and epilepsy may be of the following type: associated attacks, with migraine and seizures occurring quite independently of one another; combined attacks, with the two types of attacks succeeding one another in time; basilar artery migraine with seizures and marked EEG abnormalities; benign epilepsies with occipital discharges, migraine and intercalated seizures. We report four cases of particular interest. 相似文献