全文获取类型
收费全文 | 901篇 |
免费 | 60篇 |
国内免费 | 1篇 |
专业分类
耳鼻咽喉 | 11篇 |
儿科学 | 25篇 |
妇产科学 | 172篇 |
基础医学 | 86篇 |
口腔科学 | 14篇 |
临床医学 | 79篇 |
内科学 | 118篇 |
皮肤病学 | 5篇 |
神经病学 | 107篇 |
特种医学 | 63篇 |
外科学 | 65篇 |
综合类 | 27篇 |
预防医学 | 84篇 |
眼科学 | 25篇 |
药学 | 34篇 |
肿瘤学 | 47篇 |
出版年
2023年 | 5篇 |
2022年 | 5篇 |
2021年 | 26篇 |
2020年 | 7篇 |
2019年 | 20篇 |
2018年 | 26篇 |
2017年 | 12篇 |
2016年 | 25篇 |
2015年 | 26篇 |
2014年 | 41篇 |
2013年 | 38篇 |
2012年 | 72篇 |
2011年 | 57篇 |
2010年 | 39篇 |
2009年 | 29篇 |
2008年 | 40篇 |
2007年 | 59篇 |
2006年 | 47篇 |
2005年 | 51篇 |
2004年 | 54篇 |
2003年 | 35篇 |
2002年 | 35篇 |
2001年 | 25篇 |
2000年 | 12篇 |
1999年 | 14篇 |
1998年 | 7篇 |
1997年 | 13篇 |
1996年 | 6篇 |
1994年 | 5篇 |
1992年 | 6篇 |
1990年 | 3篇 |
1989年 | 6篇 |
1987年 | 7篇 |
1986年 | 7篇 |
1985年 | 4篇 |
1984年 | 4篇 |
1983年 | 9篇 |
1982年 | 7篇 |
1981年 | 5篇 |
1980年 | 5篇 |
1979年 | 6篇 |
1978年 | 3篇 |
1977年 | 5篇 |
1976年 | 7篇 |
1975年 | 7篇 |
1974年 | 3篇 |
1973年 | 8篇 |
1972年 | 3篇 |
1971年 | 9篇 |
1970年 | 6篇 |
排序方式: 共有962条查询结果,搜索用时 15 毫秒
1.
Lithium and memory: a review 总被引:1,自引:0,他引:1
This paper reviews systematic clinical studies suggesting memory and cognitive impairment in patients suffering from unipolar and bipolar affective disorders treated with lithium. A number of studies failed, however, to demonstrate lithium induced memory deficits. Thus, the results of studies were equivocal. This lack of empirical consensus was in part due to the heterogeneity of samples and a variety of methodological and design problems. The definition of short- and long-term memory was often arbitrary and lacked standard criteria. Some studies revealed a stability of the memory test scores over time and showed that subjective complaints of memory impairment were correlated with depression. The authors also reviewed studies examining the effects of lithium on cognition and memory of healthy control subjects. In animal research it was difficult at times to distinguish between toxic and pharmacologic effects of lithium. There is a need for prospective studies of the effect of lithium in large samples of patients using refined memory tests. 相似文献
2.
3.
Mandeep R. Mehra Patricia A. Uber Ananth Prasad Robert L. Scott Myung H. Park 《American journal of transplantation》2005,5(5):1137-1140
To identify tobacco recidivism among 86 heart transplant recipients who were smokers but demonstrated compliance with a smoking cessation program pre-transplant, we used a questionnaire and randomly tested urine for nicotine and its by-products. In 36 patients, we also evaluated circulating levels of HS-CRP, homocysteine and MPV. Twenty-eight (32.5%) of 86 patients met our definition for tobacco exposure. In this cohort, 28 (32.5%) of 86 patients met our definition for tobacco exposure. Of these 28, 12 patients self-reported tobacco use and demonstrated biochemical verification; 14 patients demonstrated only biochemical evidence of significant tobacco exposure; 2 patients self-reported tobacco use but did not demonstrate biochemical positivity. Smoking cessation within 6 months of transplantation (r = 0.52) and time post-transplantation (r = 0.43) were independent predictors for recidivism of tobacco use, p < 0.01. No differences in HS-CRP, homocysteine and MPV levels were noted among the groups. Our investigation demonstrates a high rate of tobacco recidivism among heart transplant recipients, yet few admit to it. The adverse effects of tobacco do not appear to be directly modulated by an effect on athero-thrombotic risk markers. 相似文献
4.
Ananth Shanmugam Christiane Copie-Bergman George Hashim Danielle Rebibo Jean Philippe Jais Jean-Francois Bach Marie Anne Bach Elisabeth Tournier-Lasserve 《European journal of immunology》1994,24(10):2299-2303
The T cell response against myelin basic protein (MBP) has been extensively studied in humans because of its putative role in the pathophysiology of multiple sclerosis (MS). Higher concordance rates in monozygous twins as well as an increased risk in relatives suggest the role of genetic factors in MS susceptibility. Very little is known about the shaping of T cell repertoire towards self antigens in humans and their contribution to disease susceptibility in autoimmune disorders. Here we report the comparative T cell epitope recognition patterns towards the MBP auto-antigen in healthy identical twins. We have established MBP-specific T cell lines from eight sets of twins and characterized their fine epitope specificity. Intra-pair comparison showed the co-existence of shared as well as distinct epitopes in six of eight pairs and a complete absence of concordant epitope recognition within two other pairs. These findings indicate that important differences in T cell repertoires against a self antigen may be observed between genetically identical healthy individuals, rendering difficult the interpretation of the differences which may be observed between identical twins discordant for an autoimmune disease. 相似文献
5.
6.
Chittukadu Kesavan Gajalakshmi Sundaram Krishnamurthi Revathy Ananth Viswanathan Shanta 《Cancer causes & control : CCC》1996,7(5):520-524
Uterine cervical cancer is the most common malignancy among females in developing countries, including India. The success of cervical cancer screening programs in North America and Western Europe has been the result of centralized cervical-cytology screening. This is not possible in the villages (n=17,000) of Tamilnadu where 58 percent of females in rural areas are illiterate, health infrastructure is mediocre, and cervical cytology is unknow. The present study was undertaken to examine if the village health nurse (VHN) could be trained quickly to identify a cervical abnormality by visual inspection so that we could down stage the cancer to earlier stages, more amenable to treatment. VHNs also would be trained to take an adequate Pap smear. A total of 101 VHNs were trained in batches and returned to their villages. Within two years, 6,459 engible women in the study area were screened. The agreement between the gynecologists and the VHNs in identifying cancer among those with abnormal cervix was 95 percent, and 80 percent of the Pap smears taken by VHNs were adequate by WHO criteria, making the feasibility study highly successful.Authors are with The Cancer Institute (WIA), Adyar, Madras, Tamil Nadu,India. Address correspondence to Dr Gajalakshmi, Epidemiology Division and Cancer Registry, 18, Sardar Patel Road, Cancer Institute (WIA), Madras-600 036, Tamilnadu, India. This project was funded by the Indian Council of Medical Research, Government of India, New Delhi, India.520 Cancer Causes and Control. Vol 7. 1996 相似文献
7.
8.
9.
10.