全文获取类型
收费全文 | 10751篇 |
免费 | 632篇 |
国内免费 | 72篇 |
专业分类
耳鼻咽喉 | 61篇 |
儿科学 | 268篇 |
妇产科学 | 353篇 |
基础医学 | 1400篇 |
口腔科学 | 249篇 |
临床医学 | 746篇 |
内科学 | 2441篇 |
皮肤病学 | 246篇 |
神经病学 | 964篇 |
特种医学 | 237篇 |
外科学 | 1621篇 |
综合类 | 51篇 |
一般理论 | 3篇 |
预防医学 | 918篇 |
眼科学 | 323篇 |
药学 | 490篇 |
中国医学 | 23篇 |
肿瘤学 | 1061篇 |
出版年
2023年 | 51篇 |
2022年 | 146篇 |
2021年 | 342篇 |
2020年 | 164篇 |
2019年 | 271篇 |
2018年 | 296篇 |
2017年 | 194篇 |
2016年 | 234篇 |
2015年 | 288篇 |
2014年 | 377篇 |
2013年 | 500篇 |
2012年 | 819篇 |
2011年 | 784篇 |
2010年 | 431篇 |
2009年 | 391篇 |
2008年 | 696篇 |
2007年 | 670篇 |
2006年 | 649篇 |
2005年 | 631篇 |
2004年 | 574篇 |
2003年 | 500篇 |
2002年 | 493篇 |
2001年 | 163篇 |
2000年 | 150篇 |
1999年 | 143篇 |
1998年 | 91篇 |
1997年 | 82篇 |
1996年 | 79篇 |
1995年 | 63篇 |
1994年 | 51篇 |
1993年 | 54篇 |
1992年 | 99篇 |
1991年 | 92篇 |
1990年 | 83篇 |
1989年 | 85篇 |
1988年 | 60篇 |
1987年 | 66篇 |
1986年 | 62篇 |
1985年 | 54篇 |
1984年 | 38篇 |
1983年 | 33篇 |
1982年 | 26篇 |
1979年 | 30篇 |
1978年 | 29篇 |
1977年 | 27篇 |
1975年 | 20篇 |
1974年 | 23篇 |
1973年 | 27篇 |
1971年 | 28篇 |
1969年 | 27篇 |
排序方式: 共有10000条查询结果,搜索用时 15 毫秒
1.
2.
3.
4.
5.
Takayuki Takeichi Hideaki Okajima Hiroko Suda Shintarou Hayashida Hironori Iwasaki Manuel Zeledon Ramirez Mikako Ueno Katsuhiro Asonuma Yukihiro Inomata 《Liver transplantation》2005,11(10):1285-1288
Congenital absence of the portal vein (CAPV) is a rare malformation of the splanchnic venous system. Although CAPV is usually detected in the pediatric age group, our patient was a 35-year-old woman. She had been diagnosed with CAPV in 1996 when she was 27 years old. In 1998, she was placed on hemodialysis due to chronic renal failure. After several episodes of encephalopathy in 2002, liver transplantation (LT) was recommended to her and her family. Since there was no suitable living donor candidate, she was put on the waiting list for a deceased donor liver transplant in Japan. In 2004, her ammonia level increased to around 300 microg/dl, and she went into a coma lasting for three days. After recovering from this event, she underwent a living domino transplantation using a whole liver donated by a familial amyloid polyneuropathy (FAP) patient. Her portal vein, which had drained directly into the inferior vena cava (IVC), was transected together with a cuff of the IVC wall and anastomosed to the graft liver portal vein in an end-to-end fashion. In conclusion, liver transplantation proved to be a safe and effective way to save this patient and improve her quality of life. 相似文献
6.
Mayte Ramirez Francisco Garcí a-Rí o Aleydis Vi as Concepci n Prados Jos M. Pino Jos Villamor 《The Journal of asthma》2005,41(1):109-116
The study objectives were to analyze the changes in exhaled carbon monoxide (COex) induced by histamine provocation challenge in asthmatic patients and to evaluate the relationship between COex and airway sensitivity and reactivity. Levels of COex were measured in 105 nonsmoking mildly asthmatic subjects before and after histamine provocation challenge. Dose-response curves were characterized by their sensitivity (PD20) and reactivity. Dose-response slope (DRS), continuous index of responsiveness (CIR), and bronchial reactivity index (BRI) were determined as reactivity indices. Bronchial challenge was positive for 47 subjects and negative for 58. The COex levels rose significantly after bronchial challenge in the positive response group (4.49 ± 0.4 vs. 5.74 ± 0.57 ppm, p = 0.025) and in the negative response group (2.84 ± 0.25 vs 4.00 ± 0.41 ppm, p = 0.000). An inverse relation between basal COex and PD20 was found (r = - 0.318, p = 0.030). In all subjects, a proportional direct relationship between COex and DRS (r = 0.214, p = 0.015), CIR (r = 0.401, p = 0.000), and BRI (r = 0.208, p = 0.012) was observed. On stepwise multiple linear regression analysis, COex only significantly correlated with CIR (multiple r2 = 0.174, p = 0.000). In conclusion, exhaled CO determination is a noninvasive inflammatory marker of the respiratory tract, which shows an acceptable association with airway hyperresponsiveness. 相似文献
7.
We report a case of multiple endocrine neoplasia type I and hypernephroma. Parathyroid hyperplasia, adrenocortical hyperplasia, a nodular goiter, multiple lipomas, a chromophobe adenoma of the pituitary and hypernephroma had all been diagnosed previously. All but the last are features consistent with the diagnosis of multiple endocrine neoplasia type I (Wermer's syndrome). The association of multiple endocrine neoplasia type I and hypernephroma may represent a new manifestation of this pleiotropic syndrome. 相似文献
8.
Fernanda Martini Alfredo Corallini Veronica Balatti Silvia Sabbioni Cecilia Pancaldi Mauro Tognon 《Infectious agents and cancer》2007,2(1):13-12
Simian virus 40 (SV40) is a monkey virus that was administered to human populations by contaminated vaccines which were produced
in SV40 naturally infected monkey cells. 相似文献
9.
Carmen Guillén Ponce María Pilar Garrido López María José Molina Garrido Gema Muñoz Molina Alfredo Carrato 《Clinical & translational oncology》2007,9(1):53-55
Pituitary metastases of solid tumours are infrequent, specially as a first manifestation. When they happen, they are usually
due to breast or lung cancer and are asymptomatic or produce diabetes insipidus. It is very strange that they produce hormonal
deficiency.
We present a case report of a bronchogenic adenocarcinoma in a 65-year-old man which began with panhypopituitarism, diabetes
insipidus and visual alterations. Magnetic resonance imaging revealed a large sellar mass, with clivus infiltration and invading
the right cavernous sinus. The biopsy result was adenocarcinoma metastases from lung cancer. 相似文献
10.
Modulatory effects of progesterone upon dopamine release from the corpus striatum of ovariectomized estrogen-treated rats are stereo-specific 总被引:3,自引:0,他引:3
We have shown previously that progesterone linked with bovine serum albumin at position 3 of the progesterone molecule (P-3-BSA) was effective in modulating (both stimulating and inhibiting) amphetamine (AMPH)-evoked dopamine (DA) release in vitro from superfused corpus striatal (CS) tissue fragments of ovariectomized estrogen-primed rats. To examine the stereospecificity of this effect, progesterone linked with bovine serum albumin at position 11 (P-11-BSA) and deoxycorticosterone linked with bovine serum albumin at position 21 (DOC-BSA) were tested for their ability to modulate amphetamine-stimulated DA release in vitro when administered in either a pulsatile or a continuous infusion mode at different doses. The results demonstrate that a specific orientation of the P-BSA molecule is required for differential modulation of AMPH stimulated DA release from the CS of ovariectomized estrogen-treated rats, since DOC-BSA was ineffective and P-11-BSA showed only a stimulatory effect. 相似文献