全文获取类型
收费全文 | 1470篇 |
免费 | 278篇 |
国内免费 | 17篇 |
专业分类
耳鼻咽喉 | 17篇 |
儿科学 | 61篇 |
妇产科学 | 17篇 |
基础医学 | 129篇 |
口腔科学 | 37篇 |
临床医学 | 257篇 |
内科学 | 315篇 |
皮肤病学 | 53篇 |
神经病学 | 90篇 |
特种医学 | 98篇 |
外科学 | 291篇 |
综合类 | 65篇 |
现状与发展 | 20篇 |
预防医学 | 134篇 |
眼科学 | 33篇 |
药学 | 72篇 |
中国医学 | 2篇 |
肿瘤学 | 74篇 |
出版年
2023年 | 49篇 |
2021年 | 24篇 |
2020年 | 33篇 |
2019年 | 17篇 |
2018年 | 62篇 |
2017年 | 54篇 |
2016年 | 39篇 |
2015年 | 48篇 |
2014年 | 52篇 |
2013年 | 85篇 |
2012年 | 56篇 |
2011年 | 50篇 |
2010年 | 66篇 |
2009年 | 78篇 |
2008年 | 47篇 |
2007年 | 42篇 |
2006年 | 50篇 |
2005年 | 40篇 |
2004年 | 31篇 |
2003年 | 26篇 |
2002年 | 31篇 |
2001年 | 43篇 |
2000年 | 26篇 |
1999年 | 34篇 |
1998年 | 34篇 |
1997年 | 42篇 |
1996年 | 48篇 |
1995年 | 34篇 |
1994年 | 25篇 |
1993年 | 29篇 |
1992年 | 23篇 |
1991年 | 26篇 |
1990年 | 28篇 |
1989年 | 33篇 |
1988年 | 38篇 |
1987年 | 36篇 |
1986年 | 23篇 |
1985年 | 31篇 |
1984年 | 18篇 |
1983年 | 13篇 |
1982年 | 16篇 |
1981年 | 12篇 |
1980年 | 10篇 |
1979年 | 11篇 |
1978年 | 17篇 |
1977年 | 18篇 |
1976年 | 11篇 |
1975年 | 10篇 |
1971年 | 8篇 |
1970年 | 8篇 |
排序方式: 共有1765条查询结果,搜索用时 31 毫秒
1.
V Aerra M Kuduvalli AN Moloto AK Srinivasan AD Grayson BM Fabri AY Oo 《Journal of cardiothoracic surgery》2006,1(1):6-5
Background
Atrial fibrillation can occur in up to 40% of patients undergoing coronary surgery. 相似文献2.
Paul Wexberg MD BM Richard Pacher MD Suzanne Rdler MD Katharina Kiss MD Gilbert Beran MD Michael Grimm MD Gerald Maurer MD Dietmar Glogar MD FESC 《The Journal of heart and lung transplantation》2002,21(12):583-1263
BACKGROUND: Endothelin, a peptide with strong vasoconstrictive and mitogenic properties, has been found to increase after cardiac transplantation. We therefore assessed the association between its precursor peptide, big endothelin-1, and intimal hyperplasia and coronary flow reserve after heart transplantation. METHODS: Thirty-five patients without hemodynamically significant coronary artery disease after heart transplantation were investigated: Average peak flow velocity in the left anterior descending artery (LAD) was assessed by intracoronary Doppler at baseline as well as after injection of adenosine; coronary flow reserve was calculated as a ratio of both and was corrected for patient age and baseline average peak flow velocity. Lumen, intima + media and total vessel area were measured by intracoronary ultrasound. The plasma concentration of big endothelin-1 in venous blood was determined by radioimmunoassay. RESULTS: Patients with elevated big endothelin-1 levels (>2 fmol/ml) tended to have a decreased corrected coronary flow reserve (2.60 +/- 0.9 vs 3.21 +/- 1.0, p = 0.078). They also had a significantly larger intima + media area (5.82 +/- 2.9 vs 2.37 +/- 2.9 mm(2), p = 0.004) and total vessel area (18.36 +/- 5.8 vs 12.81 +/- 4.8 mm(2), p = 0.012) than those with normal plasma concentrations. CONCLUSIONS: Our study suggests an association between elevated big endothelin-1 plasma levels and the development of intimal hyperplasia and reduction of coronary flow reserve after cardiac transplantation. 相似文献
3.
4.
5.
We have reviewed some of the factors which contribute to lung damage by various toxicants. These include disposition of the chemical, its metabolism, individual cell type susceptibility and the potential for the tissue to repair. We have discussed the use of biochemical parameters to measure the functional activity of individual cell types in order to predict the damage to specific cell types and concluded that careful morphological analysis of lung tissue is likely to provide a more sensitive and informative measure of specific cell type injury. However, in order to investigate the mechanism of toxicity of pulmonary toxicants it is essential to establish the primary biochemical event that leads to cell damage and morphological change. The importance of separating the relevant biochemical change(s) from the cascade of biochemical events associated with dead and dying cells and the reparative response of the lung is emphasised.This report results from a discussion sponsored and organised by the Advisory Subgroup in Toxicology (AST) of the European Science Foundation's Standing Committee for the European Medical Research Councils and held at the Medical Research Council Toxicology Unit, Carshalton, U. K. Those taking part were: W. N. Aldridge (AST; as above); J. Bignon (Unit for Research in Renal and Pulmonary Pathology, University of Paris, Creteil, France); P. H. Burri (Section of Developmental Biology, Institute of Anatomy, University of Berne, Switzerland); G. M. Cohen (as above); D. Dinsdale (MRC Toxicology Unit, Carshalton U. K.); P. Hedqvist (Dept. of Physiology, Karolinska Institute, Stockholm, Sweden); D. Henschler (AST; Dept. of Toxicology and Pharmacology, University of Wurzburg, FDR); G. J. Laurent (Biochemistry Unit, Cardiothoracic Institute, University of London, London, U. K.); R. Lauwerys (AST Industrial and Medical Toxicology Unit, University of Louvain, Brussels, Belgium); F. Lembeck (AST; Dept. for Experimental and Clinical Pharmacology, University of Graz, Austria); N. Lery (AST; Poison Control Centre, Lyon, France); P. Moldeus (Dept. of Forensic Medicine, Karolinska Institute, Stockholm, Sweden); B. Nemery (MRC Toxicology Unit, Carshalton, U. K.); A. Saria (Dept. for Experimental and Clinical Pharmacology, University of Graz, Austria); L. L. Smith (as above);B. Terracini (AST; Dept. of Pathology and Cancer Epidemiology, University of Turin, Italy) 相似文献
6.
A randomized controlled trial of sedation in the critically ill 总被引:2,自引:0,他引:2
LYNN PARKINSON RSCN JULIE HUGHES RSCN REA GILL MSc IMOGEN BILLINGHAM BM FRCA JANE RATCLIFFE MB ChB FRCP & IMTI CHOONARA MD MRCP 《Paediatric anaesthesia》1997,7(5):405-510
A randomized controlled trial comparing: a) a combination of oral chloral hydrate and promethazine to b) a continuous intravenous midazolam infusion, for maintenance sedation in critically ill children, was carried out. The level of sedation was assessed four hourly using a specifically devized sedation scale. Forty-four children entered the study of whom two were subsequently excluded. The number of satisfactory assessments (desired and actual levels of sedation equal) was significantly greater in the chloral hydrate and promethazine group (Chi-squared P <0.01; confidence intervals of the difference 0.06 to 0.20). The number of assessments at level 5 on the sedation scale (patient restless/distressed) was significantly greater in the midazolam group (Chi-squared P <0.05). The total number of satisfactory assessments in the two groups were only 61 and 48% respectively, suggesting that sedation can be considerably improved. Chloral hydrate and promethazine are more effective than midazolam as maintenance sedation in critically ill children. It is possible to prospectively study the efficacy of sedative drugs in critically ill children. 相似文献
7.
8.
Diagnosis of pancreatic necrosis 总被引:1,自引:0,他引:1
M C Aldridge 《The British journal of surgery》1988,75(2):99-100
9.
We report 21 cases of stress injury of the distal radial growth plate-occurring in gymnasts before skeletal maturity. The injury appears to be caused by inability of the growth plate to withstand rotational and compressive forces. Our observations have confirmed that the skeletal age of gymnasts is retarded, which increases the length of time during which the epiphysis is at risk of damage. 相似文献
10.