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目的 探讨国产加贝酯对急性水肿型胰腺炎的疗效和不良反应。 方法 应用加贝酯和一般常规治疗方法对158例年龄在20-60岁的急性水肿型胰腺炎患者进行多中心、随机、对照临床研究,其中加贝酯组81例,一般常规治疗(对照组)77例。 结果 加贝酯组显效率(74.1%)及总有效率(100%)均高于对照组(41.5%及94.8%),加贝酯组疗效显著优于对照组(P<0.01和P<0.05),且不良反应少而轻,除3例(3.7%)注射局部皮肤发红、疼痛,2例(2.4%)静脉炎,1例皮疹外,未发现肝、肾、心及血液损伤。 结论 国产加贝酯治疗急性胰腺炎起效迅速,疗效肯定,副反应少而轻。对60-80岁的急性胰腺炎患者亦有较好疗效。 相似文献
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采用显微分光光度计镜扫描法定量检测了61例正常结肠,重度不典型增生和大肠腺癌细胞核的 DNA 含量、核面积和平均吸收密度。结果表明:重度不典型增生细胞核的DNA 含量接近大肠癌,三组核面积之间差异显著(P<0.01),重度不典型增生和大肠癌的非整倍体检出率高且相近,极大部分重度不典型增生细胞已具有癌细胞的特征。研究发现:重度不典型增生实际上已处在癌的始发阶段,从而对大肠重度不典型增生的本质有了新的认识。 相似文献
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Endoscop c manometry of sphincter of Oddi(SO)and serumlevels of gastrin,glucagon,and somatostatin were measured in patients withpostcholecystectomy syndrome(n=12),asymptomatic cholecystectomised pa-tients(n=6),and controlled subjects(n=14).Pentagastrin-stimulated gastricacid secretion test was also performed in part of patients who had symptoms orno symptoms after gallbladder resection.The results showed that the patientsof symptomatic group had hypertonic dyskinesia of SO as shown by deep andwide waves superimposed on high basal pressure plateau of SO.The symptoma-tic group also had a higher serum level of gastrin and a greater BAO than tho-se of other two groups.No difference of serum levels of glucagon and soma-tostatin was found among these three groups.The hypertonic dyskinesia of SOand hypergastrinemia are considered as possibly important factors in the patho-genesis of postcholecystectomy syndrome. 相似文献
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患者女性,44岁。右季肋部不适,腹胀少尿8年,背部包块13个月,于1988年8月19日入院。患者1980年3月患无黄疸型肝炎,此后肝功能反复异常,HBsAg阳性。1982年6月出现腹胀少尿,外院B超诊断为肝硬变腹水,间断服用护肝利尿药治疗,无明显疗效... 相似文献
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