排序方式: 共有10条查询结果,搜索用时 15 毫秒
1
1.
2.
巨噬细胞在免疫反应的诱导阶段起着十分重要的作用,许多免疫反应必须有巨噬细胞的参加才能产生。抗原本身不能刺激免疫反应,需经巨噬细胞加工处理后才能刺激免疫反应的产生。这就是巨噬细胞的抗原提呈功能。 相似文献
3.
肿瘤细胞可在细胞表面表达新抗原、刺激机体产生体液免疫反应,因此,在肿瘤病人血清中经常能检测到抗原抗体复合物的存在。免疫复合物也可能因其他因素所致,但与肿瘤相关的免疫复合物仅占免疫复合物总量中的一小部分,因此抗原非特异的免疫复合物的测定对肿瘤的早期诊断和预后常常得出自相矛盾的结果。所以,测定癌病人血清中抗原特异性免疫复合物可为鉴定肿瘤抗原提供一种方法并可用于判定肿瘤预后。 相似文献
4.
Delayed-type hypersensitivity reaction (DTH) to TNCB in TNCB-primed mice was increased when mice was treated with sodium selenite. In vitro studies showed that primed T cells proliferated more vigorously when TNP-conjugated spleen adherent cells (SAC) from Se-treated mice were the stimulators as compared with SAC of untreated controls. TNP-conjugated SAC treated in vitro with sodium selenite were even stronger stimulators than SAC treated in vitro. The results indicate that Se enhances DTH by promoting antigen presentation. 相似文献
5.
6.
T细胞可通过T细胞受体和CD_2旁路途径活化。为了研究影响T细胞旁路活化途径的细胞表面分子,作者检测了分泌单克隆抗体(McAb)的杂交瘤上清对anti T11_2+anti-T11_3(anti T11_(2/3)刺激的T 细胞旁路活化途径的影响。结果发现,名叫TA/211的McAb 其本身并不激活T 细胞增殖,但能引起亚适量的anti T11_(2/3)刺激T 细胞产生强烈的增殖反应,经免疫沉淀和SDS-聚丙烯酰胺凝胶电泳分析发现,TA/211从静止T 细胞沉淀分子量为180KD、190KD、200KD 和220KD 的四条带上,表明TA/211识别人CD45分子上的共同抗原决定簇。有 相似文献
7.
硒处理小鼠能提高小鼠对致敏剂三硝基氯苯(TNCB)诱发的迟发超敏反应(DTH)的敏感性。体外实验证明,经硒处理的小鼠脾脏粘附细胞向TNCB致敏的T淋巴细胞递呈半抗原三硝基苯基进而刺激T细胞增殖反应的能力,即抗原递呈功能比未处理的对照强。正常小鼠的脾脏粘附细胞在体外经硒处理后,其递呈抗原的能力更强。提示硒通过加强抗原递呈细胞的功能实现促进DTH反应。 相似文献
8.
This paper described T cell proliferative response by an alternative pathway in normal subjects and In patients with malignant diseases. Two McAbs, Anti-CCTl and Lo-CD2-act recognizing two distinct epitopes on E-receptor (CD2) were used to costimulate PBMC. Proliferative responsiveness was measured by 3H-thymidine incorporation. It was found that 82% of 72 nonnal subjects gave proliferative response whereas only 23% of the 93 patients did. The average cpm±SD in patients with bladder cancer (118±2314), kidney cancer (1619±2719) or lymphoma (2518±4057) was significantly lower than that in normal subjects (4935±2314), (P<0.001). These results indicate that T cell proliferation through the alternative pathway was significantly depressed in patients with cancer, and this can be used as a new parameter to monitor the immune status of cancer patients. 相似文献
9.
10.
抗人全T细胞单克隆抗体大鼠杂交瘤细胞株的建立 总被引:1,自引:0,他引:1
通过融合大鼠免疫细胞株IR983F和经T细胞株HPB—ALL免疫大鼠脾细胞,获得分泌单克隆抗体LO—CD6a的杂交瘤细胞株。实验证实,LO—CD6a是人全T细胞特异性的。 相似文献
1