全文获取类型
收费全文 | 13848篇 |
免费 | 645篇 |
国内免费 | 44篇 |
专业分类
耳鼻咽喉 | 79篇 |
儿科学 | 220篇 |
妇产科学 | 312篇 |
基础医学 | 1836篇 |
口腔科学 | 254篇 |
临床医学 | 875篇 |
内科学 | 3204篇 |
皮肤病学 | 389篇 |
神经病学 | 1147篇 |
特种医学 | 658篇 |
外科学 | 2460篇 |
综合类 | 38篇 |
一般理论 | 2篇 |
预防医学 | 325篇 |
眼科学 | 169篇 |
药学 | 790篇 |
中国医学 | 30篇 |
肿瘤学 | 1749篇 |
出版年
2023年 | 89篇 |
2022年 | 167篇 |
2021年 | 254篇 |
2020年 | 166篇 |
2019年 | 188篇 |
2018年 | 215篇 |
2017年 | 190篇 |
2016年 | 223篇 |
2015年 | 246篇 |
2014年 | 326篇 |
2013年 | 427篇 |
2012年 | 652篇 |
2011年 | 787篇 |
2010年 | 413篇 |
2009年 | 335篇 |
2008年 | 712篇 |
2007年 | 743篇 |
2006年 | 656篇 |
2005年 | 730篇 |
2004年 | 706篇 |
2003年 | 710篇 |
2002年 | 672篇 |
2001年 | 367篇 |
2000年 | 434篇 |
1999年 | 333篇 |
1998年 | 175篇 |
1997年 | 149篇 |
1996年 | 164篇 |
1995年 | 141篇 |
1994年 | 144篇 |
1993年 | 97篇 |
1992年 | 254篇 |
1991年 | 262篇 |
1990年 | 223篇 |
1989年 | 260篇 |
1988年 | 228篇 |
1987年 | 221篇 |
1986年 | 195篇 |
1985年 | 159篇 |
1984年 | 109篇 |
1983年 | 85篇 |
1981年 | 54篇 |
1979年 | 82篇 |
1978年 | 80篇 |
1977年 | 61篇 |
1975年 | 59篇 |
1974年 | 54篇 |
1972年 | 58篇 |
1971年 | 59篇 |
1968年 | 51篇 |
排序方式: 共有10000条查询结果,搜索用时 15 毫秒
1.
2.
3.
Takahiro Namiki Chika Takano Ryoji Aoki Quang Duy Trinh Ichiro Morioka Satoshi Hayakawa 《Congenital anomalies》2022,62(1):38-41
Congenital rubella syndrome (CRS) results from maternal rubella virus infection in early pregnancy. Abnormal neuroimaging findings have been analyzed in a small number of CRS patients in the past; however, their clinical significance has been poorly addressed. Therefore, we have investigated the neuroimaging findings of 31 patients with CRS from previous studies. The most common finding was parenchymal calcification, which was observed in 18 of 31 patients (58.1%). A multivariable logistic regression model showed that it was associated with psychomotor or mental retardation (p = 0.018), suggesting that parenchymal calcification in CRS could be a prognostic factor. 相似文献
4.
5.
6.
7.
Hiroto Kinoshita Hitomi Nishioka Aya Ikeda Kyoko Ikoma Yoichi Sameshima Hidehisa Ohi Mizuki Tatsuno Junka Kouyama Chiaki Kawamoto Tomohiro Mitsui Yuko Tamura Yu Hashimoto Masashi Nishio Tsuyoshi Ogashiwa Yusuke Saigusa Shin Maeda Hideaki Kimura Reiko Kunisaki Kazuhiko Koike 《Journal of gastroenterology and hepatology》2019,34(11):1929-1939
8.
9.
10.
Masahiro Yamauchi Hiroko Kusano Etsuko Saito Takeshi Iwata Masashi Nakakura Yasuki Kato Takaaki Uochi Shiro Akinaga Noboru Aoki 《Journal of controlled release》2006,114(2):268-275
Previously, we demonstrated that wrapping dextran fluorescein anionic/cationic lipid complexes with neutral lipids produced a stable formulation that markedly increased the duration of the compound in plasma after intravenous administration to rats. The improved drug-delivery properties of the wrapped liposomes (WL) relative to other formulations suggested that this technology could offer important advantages for the administration of other polyanionic drugs, including antisense oligodeoxynucleotides (ODN). In the present study, we investigated the value of WL for formulating fluorescence-labeled phosphorothioated ODN (F-ODN). WL encapsulating F-ODN/cationic lipid complexes were prepared efficiently using similar methodology to that used in our earlier study. Studies confirmed that these WL were stable in vitro. Following intravenous administration to mice, free F-ODN and naked F-ODN/cationic lipid complexes were rapidly eliminated whereas administration of the WL resulted in high blood concentrations of drug that were maintained for several hours. Additional studies were conducted in mice that were inoculated with tumor cells (Caki-1 xenograft model, human kidney); in these experiments, intravenous administration of WL delivered 13 times more F-ODN to the tumor site than achieved after injection of free F-ODN. 相似文献