全文获取类型
收费全文 | 7094篇 |
免费 | 325篇 |
国内免费 | 19篇 |
专业分类
耳鼻咽喉 | 185篇 |
儿科学 | 217篇 |
妇产科学 | 203篇 |
基础医学 | 1227篇 |
口腔科学 | 124篇 |
临床医学 | 520篇 |
内科学 | 1355篇 |
皮肤病学 | 152篇 |
神经病学 | 735篇 |
特种医学 | 371篇 |
外国民族医学 | 3篇 |
外科学 | 968篇 |
综合类 | 30篇 |
一般理论 | 2篇 |
预防医学 | 361篇 |
眼科学 | 231篇 |
药学 | 363篇 |
中国医学 | 74篇 |
肿瘤学 | 317篇 |
出版年
2022年 | 43篇 |
2021年 | 83篇 |
2020年 | 71篇 |
2019年 | 103篇 |
2018年 | 111篇 |
2017年 | 86篇 |
2016年 | 120篇 |
2015年 | 157篇 |
2014年 | 178篇 |
2013年 | 242篇 |
2012年 | 365篇 |
2011年 | 366篇 |
2010年 | 257篇 |
2009年 | 228篇 |
2008年 | 337篇 |
2007年 | 334篇 |
2006年 | 349篇 |
2005年 | 338篇 |
2004年 | 324篇 |
2003年 | 345篇 |
2002年 | 306篇 |
2001年 | 111篇 |
2000年 | 102篇 |
1999年 | 113篇 |
1998年 | 88篇 |
1997年 | 72篇 |
1996年 | 43篇 |
1995年 | 55篇 |
1994年 | 36篇 |
1993年 | 37篇 |
1992年 | 53篇 |
1991年 | 46篇 |
1990年 | 48篇 |
1989年 | 41篇 |
1988年 | 56篇 |
1987年 | 46篇 |
1986年 | 38篇 |
1985年 | 57篇 |
1984年 | 37篇 |
1983年 | 32篇 |
1979年 | 34篇 |
1978年 | 33篇 |
1977年 | 35篇 |
1975年 | 33篇 |
1933年 | 36篇 |
1932年 | 29篇 |
1930年 | 38篇 |
1929年 | 45篇 |
1928年 | 42篇 |
1922年 | 32篇 |
排序方式: 共有7438条查询结果,搜索用时 78 毫秒
1.
2.
Harinakshi Sanikini David C. Muller Marisa Sophiea Sabina Rinaldi Antonio Agudo Eric J. Duell Elisabete Weiderpass Kim Overvad Anne Tjønneland Jytte Halkjær Marie-Christine Boutron-Ruault Franck Carbonnel Iris Cervenka Heiner Boeing Rudolf Kaaks Tilman Kühn Antonia Trichopoulou Georgia Martimianaki Anna Karakatsani Valeria Pala Domenico Palli Amalia Mattiello Rosario Tumino Carlotta Sacerdote Guri Skeie Charlotta Rylander María-Dolores Chirlaque López Maria-Jose Sánchez Eva Ardanaz Sara Regnér Tanja Stocks Bas Bueno-de-Mesquita Roel C.H. Vermeulen Dagfinn Aune Tammy Y.N. Tong Nathalie Kliemann Neil Murphy Marc Chadeau-Hyam Marc J. Gunter Amanda J. Cross 《International journal of cancer. Journal international du cancer》2020,146(4):929-942
Obesity has been associated with upper gastrointestinal cancers; however, there are limited prospective data on associations by subtype/subsite. Obesity can impact hormonal factors, which have been hypothesized to play a role in these cancers. We investigated anthropometric and reproductive factors in relation to esophageal and gastric cancer by subtype and subsite for 476,160 participants from the European Prospective Investigation into Cancer and Nutrition cohort. Multivariable hazard ratios (HRs) and 95% confidence intervals (CIs) were estimated using Cox models. During a mean follow-up of 14 years, 220 esophageal adenocarcinomas (EA), 195 esophageal squamous cell carcinomas, 243 gastric cardia (GC) and 373 gastric noncardia (GNC) cancers were diagnosed. Body mass index (BMI) was associated with EA in men (BMI ≥30 vs. 18.5–25 kg/m2: HR = 1.94, 95% CI: 1.25–3.03) and women (HR = 2.66, 95% CI: 1.15–6.19); however, adjustment for waist-to-hip ratio (WHR) attenuated these associations. After mutual adjustment for BMI and HC, respectively, WHR and waist circumference (WC) were associated with EA in men (HR = 3.47, 95% CI: 1.99–6.06 for WHR >0.96 vs. <0.91; HR = 2.67, 95% CI: 1.52–4.72 for WC >98 vs. <90 cm) and women (HR = 4.40, 95% CI: 1.35–14.33 for WHR >0.82 vs. <0.76; HR = 5.67, 95% CI: 1.76–18.26 for WC >84 vs. <74 cm). WHR was also positively associated with GC in women, and WC was positively associated with GC in men. Inverse associations were observed between parity and EA (HR = 0.38, 95% CI: 0.14–0.99; >2 vs. 0) and age at first pregnancy and GNC (HR = 0.54, 95% CI: 0.32–0.91; >26 vs. <22 years); whereas bilateral ovariectomy was positively associated with GNC (HR = 1.87, 95% CI: 1.04–3.36). These findings support a role for hormonal pathways in upper gastrointestinal cancers. 相似文献
3.
Oliver Sartor MD Daniel Heinrich MD Neil Mariados MD Maria José Méndez Vidal MD Daniel Keizman MD Camilla Thellenberg Karlsson MD Avivit Peer MD Giuseppe Procopio MD Stephen J. Frank MD Kalevi Pulkkanen MD Eli Rosenbaum MD Stefano Severi MD José Trigo MD Lucia Trandafir MD Volker Wagner MD Rui Li MS Luke T. Nordquist MD 《The Prostate》2019,79(14):1683-1691
4.
Julie A. Schmidt Georgina K. Fensom Sabina Rinaldi Augustin Scalbert Paul N. Appleby David Achaintre Audrey Gicquiau Marc J. Gunter Pietro Ferrari Rudolf Kaaks Tilman Kühn Heiner Boeing Antonia Trichopoulou Anna Karakatsani Eleni Peppa Domenico Palli Sabina Sieri Rosario Tumino Bas Bueno-de-Mesquita Antonio Agudo Maria-Jose Sánchez María-Dolores Chirlaque Eva Ardanaz Nerea Larrañaga Aurora Perez-Cornago Nada Assi Elio Riboli Konstantinos K. Tsilidis Timothy J. Key Ruth C. Travis 《International journal of cancer. Journal international du cancer》2020,146(3):720-730
Metabolomics may reveal novel insights into the etiology of prostate cancer, for which few risk factors are established. We investigated the association between patterns in baseline plasma metabolite profile and subsequent prostate cancer risk, using data from 3,057 matched case–control sets from the European Prospective Investigation into Cancer and Nutrition (EPIC). We measured 119 metabolite concentrations in plasma samples, collected on average 9.4 years before diagnosis, by mass spectrometry (AbsoluteIDQ p180 Kit, Biocrates Life Sciences AG). Metabolite patterns were identified using treelet transform, a statistical method for identification of groups of correlated metabolites. Associations of metabolite patterns with prostate cancer risk (OR1SD) were estimated by conditional logistic regression. Supplementary analyses were conducted for metabolite patterns derived using principal component analysis and for individual metabolites. Men with metabolite profiles characterized by higher concentrations of either phosphatidylcholines or hydroxysphingomyelins (OR1SD = 0.77, 95% confidence interval 0.66–0.89), acylcarnitines C18:1 and C18:2, glutamate, ornithine and taurine (OR1SD = 0.72, 0.57–0.90), or lysophosphatidylcholines (OR1SD = 0.81, 0.69–0.95) had lower risk of advanced stage prostate cancer at diagnosis, with no evidence of heterogeneity by follow-up time. Similar associations were observed for the two former patterns with aggressive disease risk (the more aggressive subset of advanced stage), while the latter pattern was inversely related to risk of prostate cancer death (OR1SD = 0.77, 0.61–0.96). No associations were observed for prostate cancer overall or less aggressive tumor subtypes. In conclusion, metabolite patterns may be related to lower risk of more aggressive prostate tumors and prostate cancer death, and might be relevant to etiology of advanced stage prostate cancer. 相似文献
5.
Doing it right the first time: quality improvement and the contaminant blood culture. 总被引:5,自引:3,他引:2
下载免费PDF全文
![点击此处可从《Journal of clinical microbiology》网站下载免费的PDF全文](/ch/ext_images/free.gif)
F I Weinbaum S Lavie M Danek D Sixsmith G F Heinrich S S Mills 《Journal of clinical microbiology》1997,35(3):563-565
The aim of the project was to determine whether the rate of contaminant blood cultures could be reduced by using a team of dedicated phlebotomists. Comparisons were made between adult patients requiring blood cultures for suspected bacteremia on medical and surgical units before and after the introduction and withdrawal of a dedicated blood culture team. The results showed that a significant reduction in the contaminant blood culture rate was achieved by the blood culture team (P < 0.001; chi(2) test). Therefore, in our experience, the rate of contaminant blood cultures can be reduced in a teaching hospital by using a team of dedicated phlebotomists. Calculations made with our data and those published by others suggest that cost savings from reducing false-positive blood cultures are greater than the cost of the blood culture team. 相似文献
6.
Heinrich Többen 《International journal of legal medicine》1940,34(1-3):186-208
Ohne ZusammenfassungReferat.HerrBuhtz-Breslau berichtet über den Fall Wolff-Breslau. Die klar überlegte Mordtat des frühreifen Jugendlichen hatte den Anlaß zu dem Gesetz über jugendliche Schwerverbrecher gebildet.HerrRücker-Hamburg berichtet über einen Arzt, der das Opfer einer Hysterica geworden war. Bei einer erregten Auseinandersetzung hatte er die Frau mit dem ihr entrissenen und gegen ihn gezückten Dolch niedergestoßen und getötet. Der Täter hatte 18 Jahre unter fremdem Namen in China das große Hospital einer deutsch-evangelischen Mission geleitet. Nach Verurteilung zu 2 Jahren Gefängnis und erlangter Bewährungsfrist ist er nach China zurückgekehrt. 相似文献
7.
Ferdinand Heinrich Koss 《Journal of molecular medicine (Berlin, Germany)》1938,17(44):1537-1538
Ohne Zusammenfassung 相似文献
8.
Beta2-Microglobulin 总被引:1,自引:0,他引:1
Among the uremic toxins in the "middle molecule" range, beta2-microglobulin (β2-M) is certainly one of the most frequently studied compounds. Its serum level increases with the progression of chronic kidney disease, to reach very high concentrations in patients with end-stage kidney disease. It is the major protein component of dialysis-related amyloidosis, a dramatic complication which results from high extracellular concentration and posttranslational modification of β2-M and a number of other promoters of amyloid fibril formation and deposition in osteo-articular tissues. Effective removal of β2-M can be achieved with highly effective hemodialysis and hemodiafiltration techniques but predialysis session serum levels cannot be normalized. The prevalence and severity of β2-M amyloidosis appear to have decreased in the last 20 years, although its occurrence may simply be delayed. 相似文献
9.
10.
Philipp Pohlenz Marco Blessmann Felix Blake Sven Heinrich Rainer Schmelzle Max Heiland 《Oral surgery, oral medicine, oral pathology, oral radiology, and endodontics》2007,103(3):412-417
OBJECTIVES: Intraoperative cone-beam computerized tomography (CBCT) imaging has been introduced in oral and maxillofacial surgery. Using midfacial fractures as the pioneer model, this study describes the spectrum of further promising clinical indications for intraoperative CBCT and a clinical combination with intraoperative navigation. STUDY DESIGN: One hundred seventy-nine patients admitted for surgical treatment of the facial skeleton were included in the study. Intraoperatively, 3-dimensional images were generated with the mobile CBCT scanner Arcadis Orbic 3D, obtained from Siemens Medical Solutions, in a variety of indications. RESULTS: The acquisition of the data sets was uncomplicated, and image quality was sufficient to assess the postoperative result in all cases. In the example of a facial gunshot injury, a navigation system for intraoperative localization of the metal foreign bodies was used. 相似文献