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1.
A. HAZIOT I. KATZ G. W. RONG X. Y. LIN J. SILVER & S. M. GOYERT 《Scandinavian journal of immunology》1997,46(3):242-245
Membrane-bound CD14 acts as a receptor for lipopolysaccharide (LPS) on monocytes/macrophages and neutrophils. Studies have suggested that the activation of monocytes/macrophages by the binding of LPS to membrane-bound CD14 may require the association of a signal-transducing molecule with membrane-bound CD14. The observation that non-CD14 expressing cells, such as endothelial cells, can nevertheless be activated by a complex of LPS and a soluble form of CD14 (sCD14) suggests that the receptor for this complex may be identical to the signal transducing molecule associated with membrane-bound CD14. The studies described show that two CD14-specific MoAb are able to block the LPS-induced activation of endothelial cells but do not affect the response of monocytes to LPS. This suggests that the interaction of the sCD14:LPS complex with endothelial cells is distinct from the interaction of membrane-bound CD14 with its putative signal-transducing molecule. 相似文献
2.
Fulminant hepatic failure associated with aplastic anaemia after treatment with danazol. Case report
T. NAKAJIMA Consultant N. MIZUSHIMA Registrar H. MATSUDA Registrar M. MATSUMOTO Registrar K. TAMAKOSHI Senior Registrar H. ISHII Consultant S. MORIOKA Consultant K. KANAI Associate Professor Y. IKEDA Senior Lecturer T. TERAO Associate Professor 《BJOG : an international journal of obstetrics and gynaecology》1986,93(9):1013-1015
3.
Coagulation screening before epidural analgesia in pre-eclampsia 总被引:1,自引:0,他引:1
A questionnaire survey of current practice at a small cross-section of obstetric units, covering 22% of all United Kingdom deliveries, revealed a marked lack of standard practice regarding requests for coagulation screens on pre-eclamptic patients who require epidural procedures. A retrospective audit was therefore carried out on 434 coagulation screens requested for pre-eclamptic patients in whom epidural analgesia might have been considered. Borderline abnormalities of coagulation were found in only 10 patients (2%). Platelet counts of less than 150 x 10(9)/litre were present in 28% of cases. 'Significant' thrombocytopenia (less than 100 x 10(9)/litre) and all coagulation abnormalities were only encountered in severe pre-eclampsia (diastolic blood pressure of greater than 110 mmHg and proteinuria of + + or greater). Furthermore, coagulation abnormality was always associated with a reduced platelet count (mean, 97 x 10(9)/litre). This study would therefore support anaesthetic practice which restricted any requests for coagulation testing to severe pre-eclamptic patients only. For these patients first line testing could be limited to a platelet count. 相似文献
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Urinary tract injuries during obstetric intervention 总被引:11,自引:0,他引:11
Dhanasekaran Rajasekar Supervisory Senior House Officer Marion Hall Consultant 《BJOG : an international journal of obstetrics and gynaecology》1997,104(6):731-734
A retrospective case record review of obstetric urinary tract injury in the Grampian region from 1976 to 1993 identified 16 cases of bladder injury (0.1 per 1000 deliveries, 1.4 per 1000 caesarean sections and four cases of ureteric injury (0.03 per 1000 deliveries, 0.27 per 1000 caesarean sections). Diagnosis of bladder injury was immediate, but of ureteric injury often delayed. Although the injury rates are lower than previously reported and previously reported risk factors not confirmed, this audit has resulted in guidelines for junior staff, compliance with which will be monitored, and every case of urinary tract injury will be reviewed. 相似文献
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M. D. Kilby Senior Lecturer/Consultant D. T. Howe Consultant/Honorary Senior Lecturer J. M. McHugo Consultant M. J. Whittle Professor/Head of Department 《BJOG : an international journal of obstetrics and gynaecology》1997,104(8):939-942
Oligohydramnios-polyhydramnios sequence in twin pregnancies may be managed by aggressive amniocentesis and is described in nine consecutive cases. In four of the nine pregnancies both twins survived, one pair died in the neonatal period, and the other four pairs all suffered intrauterine death. The median number of amnioreductions performed was five (range 2–7). In this series the reaccumulation of urine in the bladder of the 'stuck twin' was a predictive prognostic marker of survival in both twins, with a sensitivity and specificity of 100%. 相似文献
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Brendan McCormack BSc DPSN PGCEA RGN RMN Clinical Lecturer in Nursing 《Journal of advanced nursing》1992,17(2):187-197
The research describes how nursing staff on a general surgical ward in a district general hospital perceived the delivery method of nursing care in practice. The study design was based on ethnographic methods and data were collected by diary keeping and semi-structured interviews. An organizational method based on the principles of primary nursing had been implemented on the ward for 2 years prior to the study commencing. As well as talking in general terms about primary nursing, the nursing staff talked at some length about specific issues related to their practice. 相似文献