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排序方式: 共有860条查询结果,搜索用时 15 毫秒
1.
The authors presented some data on the platelet deforming ability in patients with acute and chronic renal failure treated with hemodialysis. Platelet deformity was studied by means of a proposed method of the filtration of platelet suspension through glass filtering funnels with a porous plate (GOST 9775-69). The deterioration of platelet deformity in patients with uremia and its direct correlation with a degree of nitremia were established. It was assumed that the deterioration of platelet deformity resulted in premature cell destruction and anemia development. Platelet deformity can be used as a test to characterize platelet function in patients with renal failure. The problem of the appropriateness of trental therapy was discussed. 相似文献
2.
Anastasios Dondos Evgenia Pierri Labros Skartsis Christos Economou 《Macromolecular chemistry and physics.》1988,189(7):1685-1692
A relation is proposed which yields the occupied volume by macromolecular chains in solution. The experimental verification of the model is carried out by a viscometric study of the ternary system polymer A/polymer B/solvent. More precisely the viscometric study permits the determination of the critical concentration c** corresponding to the incipient overlap of spherical coils. 相似文献
3.
O. M. Efremov N. A. Kalinina A. V. Sorokin 《Bulletin of experimental biology and medicine》1979,88(2):859-861
The effect of sodium salicylate, acetylsalicyclic acid, aminopyrine, and phenazone on the ability of granulocytes to produce endogenous pyrogen was studied. Experiments in vitro with verification of the viability of the leukocytes showed that of these antipyretics only sodium salicylate inhibited pyrogen formation.Department of General Pathology, Scientific-Research Institute of Experimental Medicine, Academy of MedicalSciences of the USSR, Leningrad. (Presented by Academician of the Academy of Medical Sciences of the USSR P. N. Veselkin.) Translated from Byulleten' Éksperimental'noi Biologii i Meditsiny, Vol. 88, No. 8, pp. 166–168, August, 1979. 相似文献
4.
Neonatal treatments can disrupt prepulse inhibition (PPI) of startle response later in life. Alpha2A-adrenergic receptors (alpha2A-ARs) regulate the release of brain neurotransmitters that may influence PPI. The authors examined the effects of short-term reduction in the neonatal brainstem alpha2A-ARs on subsequent development of this receptor system and acoustic startle reflex in rats. Administration of antisense oligodeoxynucleotide complementary to the alpha2A-ARs on Days 2-4 of life reduced receptor expression in the brainstem by Day 5. The treatment increased alpha2-AR numbers in the cortex, hippocampus, and amygdala at 40 days of age, and in cortex and hypothalamus at 90 days of age. Transient increases in hippocampal and amygdalar alpha2-ARs were accompanied by attenuation of acoustic startle response and impairment of PPI. 相似文献
5.
Schijman A Colina R Mukomolov S Kalinina O García L Broor S Bhupatiraju AV Karayiannis P Khan B Mogdasy C Cristina J 《Clinical and diagnostic laboratory immunology》2004,11(2):433-435
Hepatitis C virus genotyping was assessed for 257 chronic hepatitis C patients with viral loads above 1,000 IU/ml. Twelve patients were coinfected with more than one genotype. Their median viral loads did not differ significantly from those observed for monoinfected patients, which in turn did not vary significantly among different genotypes. 相似文献
6.
A. P. Avtsyn V. A. Shakhlamov R. S. Trager N. A. Kalinina I. R. Balyn' T. B. Timashkevich G. P. Polyakova 《Bulletin of experimental biology and medicine》1976,82(1):1045-1048
In a series of experiments 2250 tadpoles were infected with three strains of NAG vibrios. It can be concluded from the results of bacteriological and pathomorphological electron-microscopic and light-optical investigations that during the first 2 days the animals develop and recover from an acute infection, but the vibrios later persist for a long time in the body of the tadpoles and are excreted with the feces into the surrounding medium.Translated from Byulleten' Éksperimental'noi Biologii i Meditsiny, Vol. 82, No. 7, pp. 841–843, July, 1976. 相似文献
7.
Sutyagin PV Kalinina EE Pylaev AS 《Bulletin of experimental biology and medicine》2005,140(2):238-242
Distribution of 3H-dopamine and 3H-DAGO binding sites was studied by autoradiography on semithin sections of total preparations of rat sinoatrial node. The
relative density of 3H-dopamine and 3H-DAGO binding sites in the functional nucleus of the sinoatrial node was minimum and increased in the cranial and caudal
directions. The level of 3H-dopamine binding in the perinodal atrial myocardium was appreciably lower (22±6%), while binding of 3H-DAGO was similar (76±16%) to that in the periarterial zone of the sinoatrial node.
__________
Translated from Byulleten' Eksperimental'noi Biologii i Meditsiny, Vol. 140, No. 8, pp. 210–214, August, 2005 相似文献
8.
Nikolaos Athanasiou Katerina Baou Eleni Papandreou Georgia Varsou Anastasia Amfilochiou Elisavet Kontou Athanasia Pataka Konstantinos Porpodis Ioanna Tsiouprou Evangelos Kaimakamis Serafeim-Chrysovalantis Kotoulas Evgenia Katsibourlia Christina Alexopoulou Izolde Bouloukaki Meropi Panagiotarakou Aspasia Dermitzaki Nikolaos Charokopos Kyriakh Pagdatoglou Kallirroi Lamprou Sofia Pouriki Foteini Chatzivasiloglou Zoi Nouvaki Alexandra Tsirogianni Ioannis Kalomenidis Paraskevi Katsaounou Emmanouil Vagiakis 《Journal of sleep research》2023,32(1):e13656
Growing evidence suggests that sleep could affect the immunological response after vaccination. The aim of this prospective study was to investigate possible associations between regular sleep disruption and immunity response after vaccination against coronavirus disease 2019 (COVID-19). In total, 592 healthcare workers, with no previous history of COVID-19, from eight major Greek hospitals were enrolled in this study. All subjects underwent two Pfizer–BioNTech messenger ribonucleic acid (mRNA) COVID-19 vaccine BNT162b2 inoculations with an interval of 21 days between the doses. Furthermore, a questionnaire was completed 2 days after each vaccination and clinical characteristics, demographics, sleep duration, and habits were recorded. Blood samples were collected and anti-spike immunoglobulin G antibodies were measured at 20 ± 1 days after the first dose and 21 ± 2 days after the second dose. A total of 544 subjects (30% males), with median (interquartile range [IQR]) age of 46 (38–54) years and body mass index of 24·84 (22.6–28.51) kg/m2 were eligible for the study. The median (IQR) habitual duration of sleep was 6 (6–7) h/night. In all, 283 participants (52%) had a short daytime nap. In 214 (39.3%) participants the Pittsburgh Sleep Quality Index score was >5, with a higher percentage in women (74·3%, p < 0.05). Antibody levels were associated with age (r = −0.178, p < 0.001), poor sleep quality (r = −0.094, p < 0.05), insomnia (r = −0.098, p < 0.05), and nap frequency per week (r = −0.098, p < 0.05), but after adjusting for confounders, only insomnia, gender, and age were independent determinants of antibody levels. It is important to emphasise that insomnia is associated with lower antibody levels against COVID-19 after vaccination. 相似文献
9.
Elena V. Suntsova Alexey A. Maschan Dina D. Baydildina Irina I. Kalinina Uliana N. Petrova Alexey V. Pshonkin Galina A. Novichkova 《Pediatric blood & cancer》2019,66(6)
We retrospectively analyzed sequential therapy with romiplostim and eltrombopag in 23 children with immune thrombocytopenia: switching from romiplostim to eltrombopag (10 patients) or vice versa (13 patients). The median age of patients at enrollment in the study was 5.6 years (2‐15 years). Switching from romiplostim to eltrombopag was effective in eight (80%) patients, whereas switching from eltrombopag to romiplostim was effective in eight (62%) patients. The response rate was similar in patients failing the first thrombopoietin receptor agonist and those who had previous response. To date, all responders continue to maintain platelets over 50 × 109/L at 13‐39 months after switching. 相似文献
10.
Marina Aznaourova Nils Schmerer Harshavardhan Janga Zhenhua Zhang Kim Pauck Judith Bushe Sarah M. Volkers Daniel Wendisch Philipp Georg Evgenia Ntini Michelle Aillaud Margrit Gündisch Elisabeth Mack Chrysanthi Skevaki Christian Keller Christian Bauer Wilhelm Bertrams Annalisa Marsico Andrea Nist Thorsten Stiewe Achim D. Gruber Clemens Ruppert Yang Li Holger Garn Leif E. Sander Bernd Schmeck Leon N. Schulte 《Proceedings of the National Academy of Sciences of the United States of America》2022,119(36)