全文获取类型
收费全文 | 5694篇 |
免费 | 360篇 |
国内免费 | 10篇 |
专业分类
耳鼻咽喉 | 68篇 |
儿科学 | 220篇 |
妇产科学 | 88篇 |
基础医学 | 646篇 |
口腔科学 | 335篇 |
临床医学 | 376篇 |
内科学 | 1562篇 |
皮肤病学 | 238篇 |
神经病学 | 377篇 |
特种医学 | 93篇 |
外国民族医学 | 1篇 |
外科学 | 724篇 |
综合类 | 23篇 |
一般理论 | 1篇 |
预防医学 | 432篇 |
眼科学 | 119篇 |
药学 | 423篇 |
中国医学 | 26篇 |
肿瘤学 | 312篇 |
出版年
2023年 | 29篇 |
2022年 | 43篇 |
2021年 | 170篇 |
2020年 | 71篇 |
2019年 | 157篇 |
2018年 | 196篇 |
2017年 | 122篇 |
2016年 | 108篇 |
2015年 | 133篇 |
2014年 | 180篇 |
2013年 | 232篇 |
2012年 | 359篇 |
2011年 | 395篇 |
2010年 | 210篇 |
2009年 | 210篇 |
2008年 | 265篇 |
2007年 | 330篇 |
2006年 | 300篇 |
2005年 | 330篇 |
2004年 | 317篇 |
2003年 | 281篇 |
2002年 | 279篇 |
2001年 | 181篇 |
2000年 | 225篇 |
1999年 | 162篇 |
1998年 | 59篇 |
1997年 | 39篇 |
1996年 | 33篇 |
1995年 | 22篇 |
1994年 | 22篇 |
1993年 | 19篇 |
1992年 | 85篇 |
1991年 | 79篇 |
1990年 | 75篇 |
1989年 | 69篇 |
1988年 | 47篇 |
1987年 | 39篇 |
1986年 | 31篇 |
1985年 | 27篇 |
1984年 | 14篇 |
1983年 | 12篇 |
1982年 | 8篇 |
1979年 | 6篇 |
1978年 | 10篇 |
1975年 | 8篇 |
1974年 | 6篇 |
1973年 | 6篇 |
1970年 | 7篇 |
1968年 | 11篇 |
1966年 | 5篇 |
排序方式: 共有6064条查询结果,搜索用时 46 毫秒
1.
2.
Juan D. Gonzalez‐Sanz 《Nursing philosophy》2020,21(4)
The current situation in which the humanities are disparaged affects all university disciplines, including nursing, in whose historical evolution the humanities have always been present in one form or another. Looking beyond this disrepute, this study proposes that nursing renew its attention to classical philosophy. Specifically, it invites a close reading of Xenophon's Anabasis and Plato's Meno, to get three related goals: to show how the use of ancient texts are very valuable tools for the philosophical initiation of nursing students and can help them reflect on their choice of nursing as a practical activity; to reflect on the problem of virtue and the nature of the good life; and to show how the interaction with ancient texts allows students to reflect on questions and issues of life, theirs and others, that are not open to investigation through a purely scientific method. Consequently, both Anabasis and Meno readings strengthen the intellectual relationship between philosophy and nursing, enabling the latter to delve deeper into the key questions of its own thought as a discipline. 相似文献
3.
R. Di Raimondo J. Sanz-Esporrn R. Pl I. Sanz-Martn F. Luengo F. Vignoletti J. Nuez Mariano Sanz 《Clinical oral investigations》2020,24(7):2351-2361
To evaluate the changes in alveolar contour after guided bone regeneration (GBR) with two different combinations of biomaterials in dehiscence defects arou 相似文献
4.
Melatonin reduces oxidative stress and improves vascular function in pulmonary hypertensive newborn sheep
下载免费PDF全文
![点击此处可从《Journal of pineal research》网站下载免费的PDF全文](/ch/ext_images/free.gif)
Flavio Torres Alejandro González‐Candia Camilo Montt Germán Ebensperger Magdalena Chubretovic María Serón‐Ferré Roberto V. Reyes Aníbal J. Llanos Emilio A. Herrera 《Journal of pineal research》2015,58(3):362-373
Pulmonary hypertension of the newborn (PHN) constitutes a critical condition with severe cardiovascular and neurological consequences. One of its main causes is hypoxia during gestation, and thus, it is a public health concern in populations living above 2500 m. Although some mechanisms are recognized, the pathophysiological facts that lead to PHN are not fully understood, which explains the lack of an effective treatment. Oxidative stress is one of the proposed mechanisms inducing pulmonary vascular dysfunction and PHN. Therefore, we assessed whether melatonin, a potent antioxidant, improves pulmonary vascular function. Twelve newborn sheep were gestated, born, and raised at 3600 meters. At 3 days old, lambs were catheterized and daily cardiovascular measurements were recorded. Lambs were divided into two groups, one received daily vehicle as control and another received daily melatonin (1 mg/kg/d), for 8 days. At 11 days old, lung tissue and small pulmonary arteries (SPA) were collected. Melatonin decreased pulmonary pressure and resistance for the first 3 days of treatment. Further, melatonin significantly improved the vasodilator function of SPA, enhancing the endothelial‐ and muscular‐dependent pathways. This was associated with an enhanced nitric oxide‐dependent and nitric oxide independent vasodilator components and with increased nitric oxide bioavailability in lung tissue. Further, melatonin reduced the pulmonary oxidative stress markers and increased enzymatic and nonenzymatic antioxidant capacity. Finally, these effects were associated with an increase of lumen diameter and a mild decrease in the wall of the pulmonary arteries. These outcomes support the use of melatonin as an adjuvant in the treatment for PHN. 相似文献
5.
Miguel A. Sanz Pau Montesinos Haesook T. Kim Guillermo J. Ruiz-Argüelles María S. Undurraga María R. Uriarte Lem Martínez Rafael H. Jacomo Homero Gutiérrez-Aguirre Raul A. M. Melo Rosane Bittencourt Ricardo Pasquini Katia Pagnano Evandro M. Fagundes Edo Vellenga Alexandra Holowiecka Ana J. González-Huerta Pascual Fernández Javier De la Serna Salut Brunet Elena De Lisa José González-Campos José M. Ribera Isabel Krsnik Arnold Ganser Nancy Berliner Raul C. Ribeiro Francesco Lo-Coco Bob L?wenberg Eduardo M. Rego 《Annals of hematology》2015,94(8):1347-1356
6.
7.
8.
9.
10.
Expression of activation molecules in neutrophils, monocytes and lymphocytes from patients with unstable angina treated with stent implantation. 总被引:1,自引:0,他引:1
Víctor Sánchez-Margalet José M Cubero Consuelo Martín-Romero José Cubero José M Cruz-Fernández Raimundo Goberna 《Clinical chemistry and laboratory medicine》2004,42(3):273-278
Coronary angioplasty is known to mediate an inflammatory response. Recently, we have characterized the transient systemic inflammatory response after coronary stent implantation in patients with unstable angina by measuring different soluble protein markers. In the present study we have characterized the expression of various cellular activation markers in neutrophils, monocytes and lymphocytes from the same group of patients. Peripheral blood samples were taken before and 24 h, 48 h and 7 days after successful coronary stenting in 58 patients. Cell surface markers (CD11b/CD18 and CD38) were analyzed by flow cytometry to determine the activation of neutrophils, monocytes and T lymphocytes. We found that coronary angioplasty with stent implantation produces an increase in the cell surface expression of CD11b/CD18 in neutrophils and CD38 in monocytes, following a similar time-course with a peak after 24 h, returning to basal levels after 48 h and a second peak after 7 days. However, T lymphocytes were not found to be activated. These results suggest that coronary stent implantation induces a different pattern inducing soluble and cellular inflammation markers, and therefore, they should be taken into account in patients undergoing stent implantation to study clinical correlations. 相似文献