全文获取类型
收费全文 | 576篇 |
免费 | 46篇 |
国内免费 | 4篇 |
专业分类
耳鼻咽喉 | 1篇 |
儿科学 | 17篇 |
妇产科学 | 16篇 |
基础医学 | 87篇 |
口腔科学 | 21篇 |
临床医学 | 49篇 |
内科学 | 156篇 |
皮肤病学 | 18篇 |
神经病学 | 36篇 |
特种医学 | 6篇 |
外科学 | 39篇 |
综合类 | 10篇 |
预防医学 | 36篇 |
眼科学 | 16篇 |
药学 | 71篇 |
中国医学 | 3篇 |
肿瘤学 | 44篇 |
出版年
2024年 | 1篇 |
2023年 | 6篇 |
2022年 | 28篇 |
2021年 | 48篇 |
2020年 | 14篇 |
2019年 | 16篇 |
2018年 | 41篇 |
2017年 | 18篇 |
2016年 | 31篇 |
2015年 | 35篇 |
2014年 | 32篇 |
2013年 | 40篇 |
2012年 | 59篇 |
2011年 | 52篇 |
2010年 | 23篇 |
2009年 | 25篇 |
2008年 | 37篇 |
2007年 | 28篇 |
2006年 | 20篇 |
2005年 | 22篇 |
2004年 | 16篇 |
2003年 | 11篇 |
2002年 | 11篇 |
2000年 | 1篇 |
1999年 | 1篇 |
1998年 | 6篇 |
1997年 | 2篇 |
1996年 | 1篇 |
1995年 | 1篇 |
排序方式: 共有626条查询结果,搜索用时 16 毫秒
1.
2.
3.
Amrita Goyal MD Kristin Totoraitis MD Wael Toama MD Fiona He MD Kimberly Bohjanen MD Sarah Williams MD Daniel D. Miller MD 《Journal of cutaneous pathology》2020,47(7):643-648
Mycosis fungoides (MF) is an indolent, uncommon, non-Hodgkin T-cell lymphoma of the skin. It classically presents with patches, plaques, and tumors and may rarely show spread to internal organs or bone marrow. Up to 7.5% of MF patients may be diagnosed with a second malignancy. Intravascular large B-cell lymphoma (IVLBCL) is an exceedingly rare non-Hodgkin B-cell lymphoma characterized by predominant growth of large neoplastic cells in the lumina of blood vessels. This case presents with an unusual confluence of two rare diagnoses, MF and IVLBCL, made more remarkable by the presence of both diagnoses on a single skin biopsy sample. 相似文献
4.
Cancers have long being hallmarked as cells relying heavily on their glycolysis for energy generation in spite of having functional mitochondria. The metabolic status of the cancer cells have been revisited time and again to get better insight into the overall carcinogenesis process which revealed the apparent crosstalks between the cancer cells with the fibroblasts present in the tumour microenvironment. This review focuses on the mechanisms of transformations of normal fibroblasts to cancer-associated fibroblasts (CAF), the participation of the CAF in tumour progression with special interest to the role of CAF cellular glycolysis in the overall tumorigenesis. The fibroblasts, when undergoes the transformation process, distinctly switches to a more glycolytic phenotype in order to provide the metabolic intermediates necessary for carrying out the mitochondrial pathways of ATP generation in cancer cells. This review will also discuss the molecular mechanisms responsible for this metabolic make over promoting glycolysis in CAF cells. A thorough investigation of the pathways and molecules involved will not only help in understanding the process of activation and metabolic reprogramming in CAF cells but also might open up new targets for cancer therapy. 相似文献
5.
6.
Scotland RS Madhani M Chauhan S Moncada S Andresen J Nilsson H Hobbs AJ Ahluwalia A 《Circulation》2005,111(6):796-803
7.
8.
Bright I Nwaru Mome Mukherjee Ramyani P Gupta Angela Farr Martin Heaven Andrew Stoddart Amrita Bandyopadhyay Deborah Fitzsimmons Michael Shields Ceri Phillips George Chamberlain Colin Fischbacher Christopher Dibben Chantelle Aftab Colin R Simpson Ronan Lyons David Strachan Gwyneth A Davies Brian McKinstry Aziz Sheikh 《Journal of the Royal Society of Medicine》2015,108(11):433-439
9.
Michael J Curtis Richard A Bond Domenico Spina Amrita Ahluwalia Stephen P A Alexander Mark A Giembycz Annette Gilchrist Daniel Hoyer Paul A Insel Angelo A Izzo Andrew J Lawrence David J MacEwan Lawrence D F Moon Sue Wonnacott Arthur H Weston John C McGrath 《British journal of pharmacology》2015,172(14):3461-3471
10.
Giri Prerna Mukhopadhyay Amrita Gupta Mohini Mohapatra Bhagyalaxmi 《Heart failure reviews》2022,27(2):431-454
Heart Failure Reviews - Heart failure is a global health burden responsible for high morbidity and mortality with a prevalence of greater than 60 million individuals worldwide. One of the major... 相似文献