The Clinical and Experimental Research on Billings Ovulation Method During Breastfeeding

Objective The effectiveness and acceptability of Billings Ovulation Method (BOM) during breastfeeding were studied. At the same time, the monitoring indexes of fertility return were studied.Methods It was a clinical comparative study of BOM and IUD containing copper (200mm 2). The annual rate of pregnancy, discontinuation rate and continuation rate in the two groups was determined. The serum prolactin and estradiol in 90 breastfeeding mothers and urine estrogen and pregnanediol in different feeding mothers were measured.Results There were 219 subjects in the BOM group and 200 in the IUD group. The pregnancy rate in this two groups was 1. 43% and 1. 54% respectively. The rates of discontinuation and continuation in the IUD group were:8. 87% and 91. 35% as well as in the BOM group were 8. 53% and 90. 17% respectively. Neither result was statistically significant (P>0. 05). The experimtal research showed that menses return was well estimated by 0. 35 ratio of serum prolactin vs. estrodiol. Sensitivity and     

比林斯法在哺乳期应用的实验和临床研究

目的 :观察比林斯生育调节法 (BOM)在哺乳期避免妊娠的可行性和有效性 ,寻找监测哺乳期生育力恢复的指标。方法 :对比研究比林斯法和 IUD法在 1 2个月中的意外妊娠率、停用率和续用率。测定血生乳素、雌二醇用以估计月经恢复 ;检测尿雌激素和孕二醇 ,确定第 2次月经前是否排卵。结果 :哺乳期比林斯法和 IUD法两组妇女分别观察了 2 1 9例和 2 0 0例。妊娠率、停用率和续用率分别为 1 .43 %、1 .5 4 %,8.5 3 %、8.87%和 90 .1 7%、91 .3 5 %,两组间无统计学差异 (P>0 .0 5 )。同期进行的 90例和 2 75次血生乳素、雌二醇的测定发现 ,二者比例以 0 .3 5作为月经恢复的指标。6 1例尿雌激素和孕二醇测定表明 ,宫颈粘液类型与激素水平吻合外 ;混合喂养妇女第 2次月经前排卵发生率为 47.0 5 %。结论 :(1 ) BOM用于哺乳期避孕的效率如同 IUD法 ,也能被哺乳期妇女接受。 (2 )血生乳素和雌二醇测定可估计哺乳期妇女月经恢复 ,方法简单 ,可应用于临床。 (3 )混合喂养有延迟哺乳期生育的作用。     

The Application of Billings for Fertility Regulation Method during the Period of Breastfeeding

In order to adopt Billings Method for fertility regulation during the period of breast-feeding,cervical mucus was observed and monitored in 61 breast-feeding mothers.Urine estrogen and/or pregnanediol were/was measured in 15 breast feeding mothers.Observations on cervical mucus during 244 months were collected.The type of dry or no mucus was observed in 75.27% fully breast-feeding mothers.Constant unchanging mucus was ob-served in 69.39% partially breast-feeding mothers.Developmental changing mucus was observed in 79.25% of mothers bottle-feeding their infants.According to the record on cervical mucus within 6months postpartum,97.14% of the cervical mucus was consistent with normal menstrual cycles.Urine estrogen and /or pregnanediol were/was measured in 15 breast-feeding mothers.The level of estrogen in urine averaged 0.08 μmol/24 h in fully breast feeding mothers and 0.14 μmol/24 h in partially breast-feeding mothers.The peak level averaged 0.21 pmol/24 h in bottle-feeding mothers.The pregnanediol level was determined to confirm ovulation in bottle-feeding mothers.The average levels of cut off and the period of ovutation in 6bottle feeding mother were 7 μmol/24 h and 9 μmol/24 h respectively.Measurement of urine estrogen and pregnanediot level all matched with cervical mucus appearances.Conclusion: Billings Method is a simple,scientific method for contraception without side-effects during breast-feeding period.