血栓与止血试验的进展及标准化

血栓与止血是研究止、凝血机制及其疾病的一门边缘学科,涉及了临床医学、基础医学、分子生物学、生物化学、药理学、免疫学及其他领域。在生理条件下,机体的凝血系统、抗凝血和纤维蛋白降解系统相互制约,处于动态平衡状态,以维持正常的血液循环。因此,即使血管局部有轻微损伤,既不会     

云南灯盏花治疗肾病综合征高粘血症临床观察

肾病综合征患者血液的高粘血症的治疗一直是肾内科医生关注的问题，近2年来，我们对肾病综合征合并高粘血症的患者。给予云南灯盏花治疗，取得满意疗效，现报道如下。     

小剂量甘露醇、脑活素综合治疗新生儿缺氧缺血性脑病38例临床观察

新生儿缺氧缺血性脑病(HIE)是围产期新生儿常见的颅内病变，是新生儿早期发病和死亡的重要原因。自1998年10月起，我科在原有治疗的基础上，应用小剂量甘露醇、脑活素综合治疗中、重度HIE38例，疗效满意。现报告如下。     

壳聚糖对大黄有效成分吸附作用的研究

目的观察高分子吸附剂壳聚糖对大黄醇提液澄清吸附作用。方法以高分子壳聚糖为吸附剂,在不同条件下进行吸附澄清,通过UV法和HPLC法测定,以获得最佳实验室工艺条件。结果在温度为70℃,pH11～12,吸附剂用量小于1.5‰,吸附时间为1.5h时,澄明度最好,但对大黄素、大黄酚等有效成分的吸附率较高,含量会降低16%～40%。结论壳聚糖作为澄清剂对大黄素等有效成分有一定的吸附作用,故在实际应用中应尽量避免使用壳聚糖作为大黄或含大黄、虎杖、决明子、番泻叶、茜草等制剂的澄清剂,以保证药物的疗效。     

腰椎间盘突出症不同证候患者CT影像学特点及其与证候程度间的相关性研究

目的 研究腰椎间盘突出症(LDH)不同证候间患者CT影像学特点,分析证候程度与影像学指标的相关性。方法 选取LDH气滞血瘀证和肝肾亏虚证患者共150例,其中气滞血瘀证80例,肝肾亏虚证70例。测定并记录各证型CT影像学指标,应用中医证候量表量化证候程度,分析影像学指标与中医证候评分的相关性。结果 肝肾亏虚证患者的突出间盘CT值.高于气滞血瘀证,椎体CT值低于气滞血瘀证(P<005)。肝肾亏虚证、气.滞血,瘀证中医证候积分与髓核突出.率呈正,相关(P<0001)与侧隐窝矢状径呈负相关(P<0001)与椎体CT值、突出间盘CT值均无相关性。结论 肝肾亏虚证与气滞血瘀证LDH患者CT影像学特点不同,在一定程度上反映了患者中医证候的严重程度,为中医证候客观化辨证分型提供依据,丰富中医辨证内涵。     

171株小肠结肠耶尔森菌的病原学特征

目的研究徐州地区分离的171株小肠结肠炎耶尔森菌(Yersinia enterocolitica,Y.e)的病原学特征及其动态变化。方法通过血清学分型,生物分型,毒力基因检测,分析不同时代分离株的致病性。通过脉冲场凝胶电泳(PFGE)分析Y.e的分子流行病学特征。结果不同时代分离株的优势型别始终为O:3血清型。非致病菌型是近年分离的Y.e菌株的优势菌型。O:3血清型菌株其狗源株和人源株的PFGE带型完全相同。结论不同时代分离菌株的毒力分布特征发生了很大的变迁,O:3血清型菌株流行比较稳定,菌株变异较小。     

中药废弃物的能源化利用策略

生物质能具有可再生、资源丰富、碳中性、环境友好等优点,将典型生物质的中药废弃物高附加值转化为能源,循环应用于工业生产,既可实现废弃物的处理转化,又能达到取代化石燃料、节能降耗、增加企业利润的目的。分析中药废弃物能源化的利用策略(直接燃烧、发酵制沼气和乙醇、热解气化等),为后续深入探索和开发中药废弃物的能源高值化利用模式及拓展资源的利用途径和层次提供参考。     

老年人静脉血细胞分析参考值范围的调查研究

Objective To establish the reference range of venous blood cells of healthy aged people by means of investigation on the reference range of venous blood cells of healthy adults and the aged.Methods The parameters of 3302 venous blood samples from the healthy adults and the aged were analyzed by applying SymexKX-21N hematology analyzer,and the test results were statistically analyzed with SPSS10.0 software.Results The reference range of the healthy aged people(males and females):WBC(3.57-9.00)×109/L and(3.52-8.39)×109/L;RBC(3.78-5.42)×1012/L and (3.44-4.83)×1012/L;hemoglobin(Hb)121.40-168.10 and 107.90-147.90 g/L;hematocrit(HCT)36.62%-49.18% and 32.82%-44.03%;mean corpuscular volume(MCV)85.10-100.60 and 84.70-100.60 fL;mean corpuscular hemoglobin(MCH)28.54-34.48 and 28.20-34.10 pg;mean corpuscular hemoglobin concentration(MCHC)322.00-357.00 and 320.00-352.00 pg/L;coefficient of variation of red blood cell distribution width(RDW-CV)12.13%-15.10% and 10.20%-17.12%;platelet(PLT)(70.00-240.00)×109/L and(77.00-262.00)×109/L;mean platelet volume(MPV)9.77-15.37 and 9.51-15.55 fL;platelet distribution width(PDW)11.44%-27.77%;platelet hematocrit(PCT)1.10-2.73 and 1.13-2.99 mL/L;large platelet ratio(P-LCR)24.35%-70.14%.The differences of the parameters(WBC,RBC,Hb,HCT,MCHC,PLT and PCT)were statistically significant between senile males and senile females(P＜0.01),while the other parameters weren't(P＞0.05);the differences of parameters(WBC,MPV,PDW and P-LCR)were not significant between adults and the ageds(P＞0.05),while the other parameters were(P＜0.05).There were also significant differences(P＜0.05)between the test results and the reported date about the blood cell parameters of adults and the ageds.Conclusion The reference range of the healthy ageds is different from that of adults;therefore it is necessary to establish the laboratory reference range of venous blood cells of the elderly in this region scientifically and rationally.     

老年人静脉血细胞分析参考值范围的调查研究

Objective To establish the reference range of venous blood cells of healthy aged people by means of investigation on the reference range of venous blood cells of healthy adults and the aged.Methods The parameters of 3302 venous blood samples from the healthy adults and the aged were analyzed by applying SymexKX-21N hematology analyzer,and the test results were statistically analyzed with SPSS10.0 software.Results The reference range of the healthy aged people(males and females):WBC(3.57-9.00)×109/L and(3.52-8.39)×109/L;RBC(3.78-5.42)×1012/L and (3.44-4.83)×1012/L;hemoglobin(Hb)121.40-168.10 and 107.90-147.90 g/L;hematocrit(HCT)36.62%-49.18% and 32.82%-44.03%;mean corpuscular volume(MCV)85.10-100.60 and 84.70-100.60 fL;mean corpuscular hemoglobin(MCH)28.54-34.48 and 28.20-34.10 pg;mean corpuscular hemoglobin concentration(MCHC)322.00-357.00 and 320.00-352.00 pg/L;coefficient of variation of red blood cell distribution width(RDW-CV)12.13%-15.10% and 10.20%-17.12%;platelet(PLT)(70.00-240.00)×109/L and(77.00-262.00)×109/L;mean platelet volume(MPV)9.77-15.37 and 9.51-15.55 fL;platelet distribution width(PDW)11.44%-27.77%;platelet hematocrit(PCT)1.10-2.73 and 1.13-2.99 mL/L;large platelet ratio(P-LCR)24.35%-70.14%.The differences of the parameters(WBC,RBC,Hb,HCT,MCHC,PLT and PCT)were statistically significant between senile males and senile females(P＜0.01),while the other parameters weren't(P＞0.05);the differences of parameters(WBC,MPV,PDW and P-LCR)were not significant between adults and the ageds(P＞0.05),while the other parameters were(P＜0.05).There were also significant differences(P＜0.05)between the test results and the reported date about the blood cell parameters of adults and the ageds.Conclusion The reference range of the healthy ageds is different from that of adults;therefore it is necessary to establish the laboratory reference range of venous blood cells of the elderly in this region scientifically and rationally.