前列腺癌基因诊断芯片的临床应用

目的应用基因芯片诊断前列腺癌.方法提取前列腺癌及正常前列腺组织总DNA并纯化mRNA,以包含了9个前列腺癌相关的特异基因和1个参照基因的xy检测系统cDNA临床芯片,对前列腺癌及正常前列腺组织的基因表达谱进行分析.结果9个前列腺癌相关基因检测中癌与正常组织存在显著差异,其中显著上调的有7条;显著下调有2条.结论前列腺癌临床基因诊断芯片作为前列腺癌分子水平的诊断的方法,有望提高前列腺癌的检出率.     

应用输尿管镜放置双J管早期治疗输尿管阴道瘘

Objective To evaluate the clinical effect of placing double J stent using a ureteroscope in early managing ureterovaginal fistula.Methods Twenty-eight patients cases with ureterovaginal fistula from 2002 to 2008 were treated early with placing double J stent using a ureteroscope and the clinical data were reviewed.Results Twenty-two of 28 cases were treated and double J stent was placed in them by a uretero-scope and 75% (21/28)of cases were cured.Four of 21 cases were treated twice by a ureteroscope and were cured finally.7 cases with failure ureterovaginal treatment underwent ureterocystostomy and were cured.The follow-up from 6 months to 33 months (average 10.1±6.4 months)showed that all of the 28 cases had been cured and had no urinary fistula.Conclusion Placing double J stent using a ureteroscope is the first choice of operative procedure for the early treatment of ureterovaginal fistula.     

应用输尿管镜放置双J管早期治疗输尿管阴道瘘

Objective To evaluate the clinical effect of placing double J stent using a ureteroscope in early managing ureterovaginal fistula.Methods Twenty-eight patients cases with ureterovaginal fistula from 2002 to 2008 were treated early with placing double J stent using a ureteroscope and the clinical data were reviewed.Results Twenty-two of 28 cases were treated and double J stent was placed in them by a uretero-scope and 75% (21/28)of cases were cured.Four of 21 cases were treated twice by a ureteroscope and were cured finally.7 cases with failure ureterovaginal treatment underwent ureterocystostomy and were cured.The follow-up from 6 months to 33 months (average 10.1±6.4 months)showed that all of the 28 cases had been cured and had no urinary fistula.Conclusion Placing double J stent using a ureteroscope is the first choice of operative procedure for the early treatment of ureterovaginal fistula.     

联合方案治疗慢性难治性前列腺炎探讨

慢性前列腺炎是泌尿外科的一种难治性疾病，根据慢性前列腺炎的病因及生理特点设计联合治疗方案。通过前列腺穿刺直接给药，辅以射频仪治疗药物吸收，口服α１Ａ受体拮抗剂改善排尿症状的三联方法，提高慢性前列腺炎的治疗效果。     

两种开放术式治疗前列腺增生症术后并发症的比较

目的：探讨Ｍａｄｄｉｇａｎ术与传统术式治疗前列腺增生症术后并发症的比较。方法：以统计学方法比较两种术式中手术时间。出血量及术后各种并发症的发生率。结果：Ｍａｄｉｇａｎ手术组病人无论在术中还是术后并发症的发生率均低于传统开放手术组。结论：Ｍａｄｉｇａｎ术为前列腺增生症病人提供了一种安全、有效、经济的手术方法。     

以改良TRAP法检测人膀胱肿瘤组织中端粒酶活性表达的临床意义

目的：探讨膀胱肿瘤及癌旁组织端粒酶活性表达及临床意义。方法：以改良TRAP法测定91例膀胱癌组织标本端粒酶活性表达。结果：83例膀胱移行细胞癌组织中78例检出端粒酶活性。阳性率为94％，其对应的癌旁组织也有14％的检出率，8例膀胱乳头状瘤组织中4例检出端粒酶活性，阳性率为50％，其对应的癌旁组织检出率为12％，端粒酶活性在不同临床病理类型的膀胱肿瘤及癌旁组织中表达无显差异（P＞0．05），结论：应用非放射性的银染方法对端粒酶的活性进行检测，图像清晰，简便，安全，易于临床推广。     

端粒酶活性在人膀胱肿瘤组织中表达的临床意义

目的：探讨不同临床病理类型的膀胱肿瘤及癌旁组织端粒酶活性表达及临床意义，方法：以改良TRAP法测定91例膀胱肿瘤组织标本端粒酶活性表达。结果：83例膀胱移行细胞癌组织中78例检测到端粒酶活性，阳性率为94％，其对应的癌旁组织也有14％的检出率，8例膀胱乳头状瘤组织中4例检测到端粒酶活性，阳性率为50％，其对应的癌旁组织检出率为12％，端粒酶活性在不同临床病理类型的膀胱肿瘤及癌旁组织中表达差异无显著性意义（P＞0．05），结论：膀胱肿瘤及癌旁组织端粒酶活性的检测对肿瘤的诊断有重要意义。     

应用输尿管镜放置双J管早期治疗输尿管阴道瘘

Objective To evaluate the clinical effect of placing double J stent using a ureteroscope in early managing ureterovaginal fistula.Methods Twenty-eight patients cases with ureterovaginal fistula from 2002 to 2008 were treated early with placing double J stent using a ureteroscope and the clinical data were reviewed.Results Twenty-two of 28 cases were treated and double J stent was placed in them by a uretero-scope and 75% (21/28)of cases were cured.Four of 21 cases were treated twice by a ureteroscope and were cured finally.7 cases with failure ureterovaginal treatment underwent ureterocystostomy and were cured.The follow-up from 6 months to 33 months (average 10.1±6.4 months)showed that all of the 28 cases had been cured and had no urinary fistula.Conclusion Placing double J stent using a ureteroscope is the first choice of operative procedure for the early treatment of ureterovaginal fistula.     

慢性前列腺炎三种药物疗法的费用效果分析

目的：评价吾真宁、可乐必妥、阿奇霉素(泰力特)3种治疗慢性前列腺炎药物经济学效果。方法：对75例慢性前列腺炎病人分别应用吾真宁、可乐必妥、泰力特治疗，运用药物经济学的成本-效果分析方法进行评估。结果：无论是症状消失还是体征消失的效果，吾真宁组的成本效果比均低于可乐必妥及泰力特组。结论：吾真宁为慢性前列腺炎患者提供了一种有效、安全、经济的口服药物。     

Madigan术与传统开放术式治疗前列腺增生症术后并发症的比较

目的：比较Ｍａｄｉｎｇａｎ术与传统术式治疗前列腺增生症术后并发症。方法：以统计学方法比较两种术式中手术时间，出血量及术后各种并发症的发生率。结果：Ｍａｄｉｇａｎ手术组病人无论在术中还是在术后并发症的发生率均低于传统开放手术组。结论：Ｍａｄｉｇａｎ术为前列腺增生症病人提供了一种安全、有效、经济的手术方法。