金银花药材中抗呼吸道病毒感染的咖啡酰奎宁酸类成分的定量研究

目的:寻找金银花中的抗呼吸道病毒感染的成分,并进行定量研究。方法:采用各种柱层析和制备薄层层析等方法分离、细胞病变法进行抗病毒作用的研究,采用RP-HPLC方法进行定量方法的研究。结果:分离得到了13种咖啡酰奎宁酸类化合物和咖啡酸、咖啡酸甲酯,确认咖啡酰奎宁酸类成分具有较强的抗呼吸道病毒作用,并采用HPLC方法测定了金银花中的 6种咖啡酰奎宁酸类成分和咖啡酸的含量。结论:咖啡酰奎宁酸类成分为金银花中的有效成分,定量方法准确、重复性好。     

Causes of Recurrent Haematuria

Eighty-two patients with recurrent haematuria were investigatedand divided into five groups according to clinical and histologicalfindings. In patients with no documented history of acute nephritis,approximately equal numbers had normal renal histology, focalnephritis, and diffuse proliferative glomerulonephritis. Patientswith diffuse proliferative glomerulonephritis showed a femalepreponderance, had a higher incidence of frank haematuria, raisedsedimentation rate, and raised antistreptolysin O titre. Unlikeprevious reports, two of 26 patients with focal nephritis showeddeterioration of renal function on follow up, whilst C'3 levelswere diminished in three patients. Hypertension was observedin 10 per cent of patients with optically normal renal histologyor focal nephritis. The significance of these results are assessedin relation to those reported in the literature. ¹Senior Registrar in Clinical Medicine. ²Lecturer in Clinical Medicine. ³Senior Pathologist. ⁴Professor of Clinical Medicine.     

The Effect of Hemorrhage on Plasma Iron Turnover

The plasma iron turnover rate in rats following a single hemorrhage reachesa maximum in about 48 hours and returns to normal between the seventh andtenth day. There is considerable variation in individual rats in both the maximum rate attained and the time required for recovery. No significant difference in response was observed due to the severity of hemorrhage uponremoval of 2.7 to 18 per cent of total red cells.

Submitted on June 20, 1960 Accepted on November 20, 1960     

USE OF ESMOLOL IN THE POSTBYPASS MANAGEMENT OF HYPERTROPHIC OBSTRUCTIVE CARDIOMYOPATHY

In patients suffering from hypertrophic obstructive cardiomyopathy(HOCM), any catecholamine release during anaesthesia may aggravatethe severity of the outflow tract obstruction and compromisecardiac output. In this event the situation may be improvedby beta block. Esmolol, an ultra-shortacting beta-blocker (half-life9 minj appears to be a suitable agent for this purpose. We describeits use in the perioperative management of a patient who underwentsurgical correction of HOCM.