全文获取类型
收费全文 | 63577篇 |
免费 | 4240篇 |
国内免费 | 137篇 |
专业分类
耳鼻咽喉 | 575篇 |
儿科学 | 2547篇 |
妇产科学 | 1688篇 |
基础医学 | 8179篇 |
口腔科学 | 846篇 |
临床医学 | 9200篇 |
内科学 | 11589篇 |
皮肤病学 | 1001篇 |
神经病学 | 5994篇 |
特种医学 | 1186篇 |
外国民族医学 | 4篇 |
外科学 | 5739篇 |
综合类 | 624篇 |
一般理论 | 111篇 |
预防医学 | 8551篇 |
眼科学 | 888篇 |
药学 | 4025篇 |
中国医学 | 120篇 |
肿瘤学 | 5087篇 |
出版年
2023年 | 318篇 |
2022年 | 448篇 |
2021年 | 1283篇 |
2020年 | 845篇 |
2019年 | 1299篇 |
2018年 | 1523篇 |
2017年 | 1176篇 |
2016年 | 1267篇 |
2015年 | 1435篇 |
2014年 | 1983篇 |
2013年 | 3116篇 |
2012年 | 4424篇 |
2011年 | 4817篇 |
2010年 | 2685篇 |
2009年 | 2398篇 |
2008年 | 4256篇 |
2007年 | 4506篇 |
2006年 | 4368篇 |
2005年 | 4437篇 |
2004年 | 4205篇 |
2003年 | 3985篇 |
2002年 | 3645篇 |
2001年 | 719篇 |
2000年 | 624篇 |
1999年 | 709篇 |
1998年 | 753篇 |
1997年 | 657篇 |
1996年 | 530篇 |
1995年 | 527篇 |
1994年 | 464篇 |
1993年 | 377篇 |
1992年 | 370篇 |
1991年 | 333篇 |
1990年 | 300篇 |
1989年 | 270篇 |
1988年 | 256篇 |
1987年 | 224篇 |
1986年 | 227篇 |
1985年 | 231篇 |
1984年 | 233篇 |
1983年 | 204篇 |
1982年 | 239篇 |
1981年 | 220篇 |
1980年 | 165篇 |
1979年 | 113篇 |
1978年 | 135篇 |
1977年 | 61篇 |
1976年 | 71篇 |
1974年 | 86篇 |
1973年 | 60篇 |
排序方式: 共有10000条查询结果,搜索用时 0 毫秒
1.
Amanda Bolderston Jackie Middleton Cynthia Palmaria Susan Cauti Susan Fawcett 《Journal of Medical Imaging and Radiation Sciences》2021,52(2):160-163
Lesbian, gay, bisexual, transgender, queer and two-spirit plus (LGBTQ2S+) people have distinct healthcare needs that may be unaddressed in many undergraduate healthcare curricula. The Radiation Therapy Program (RADTH) at the University of Alberta underwent a review of the three-year didactic curriculum using an online survey. The survey sought to ascertain if, where and how topics related to LGBTQ2S + healthcare are taught. Results indicated that out of 10 RADTH program faculty respondents, three teach related topics. The total time dedicated within the three-year curriculum was approximately three and a half hours. Other findings showed that faculty are interested in receiving more education in this area and would favour discussions about how to incorporate these themes into appropriate courses. This preliminary investigation demonstrated that there has been some initial work in this area, but there is more to be done. 相似文献
2.
3.
4.
Monique G. Kumar M.Phil. M.D. Heather Ciliberto M.D. Susan J. Bayliss M.D. 《Pediatric dermatology》2015,32(2):198-200
Pediatric trachyonychia is an acquired nail disease that can cause distress to families. It is a poorly understood disease, and long‐term follow‐up data are lacking. We present an institutional review of 11 children with isolated pediatric trachyonychia followed over time. Children with the diagnosis of pediatric trachyonychia were identified and invited to participate. Pictures were taken on follow‐up and a questionnaire was answered. Exclusion criteria include having another diagnosis at the initial visit that causes nail dystrophy. Eleven patients with the diagnosis of pediatric trachyonychia were available for follow‐up. The mean age of appearance was 2.7 years (range 2–7 yrs) and the average follow‐up was 66 months (range 10–126 mos). Nine patients were treated with potent topical corticosteroids, one used only petrolatum, and one took vitamin supplements. One patient was found to have an additional skin and hair diagnosis of alopecia areata on follow‐up. On follow‐up, 82% noted improvement of the nails, whereas 18% noted no change. A majority of cases of pediatric trachyonychia are isolated and improve with time, regardless of treatment. 相似文献
5.
Susan E. Hickman Alexia M. Torke Greg A. Sachs Rebecca L. Sudore Anne L. Myers Qing Tang Giorgos Bakoyannis Bernard J. Hammes 《Journal of pain and symptom management》2019,57(6):1143-1150.e5
ContextIt is especially important that patients are well informed when making high-stakes, preference-sensitive decisions like those on the Physician Orders for Life-Sustaining Treatment (POLST) form. However, there is currently no way to easily evaluate whether patients understand key concepts when making these important decisions.ObjectivesTo develop a POLST knowledge survey.MethodsExpert (n = 62) ratings of key POLST facts were used to select items for a POLST knowledge survey. The survey was administered to nursing facility residents (n = 97) and surrogate decision-makers (n = 112). A subset (n = 135) were re-administered the survey after a standardized advance care planning discussion to assess the scale's responsiveness to change.ResultsThe 19-item survey demonstrated adequate reliability (α = 0.72.). Residents' scores (x = 11.4, standard deviation 3.3) were significantly lower than surrogate scores (x = 14.7, standard deviation 2.5) (P < 0.001). Scores for both groups increased significantly after administration of a standardized advance care planning discussion (P < 0.001). Although being a surrogate, age, race, education, cognitive functioning, and health literacy were significantly associated with higher POLST Knowledge Survey scores in univariate analyses, only being a surrogate (P < 0.001) and being white (P = 0.028) remained significantly associated with higher scores in multivariate analyses.ConclusionThe 19-item POLST Knowledge Survey demonstrated adequate reliability and responsiveness to change. Findings suggest the survey could be used to identify knowledge deficits and provide targeted education to ensure adequate understanding of key clinical decisions when completing POLST. 相似文献
6.
7.
8.
9.
Melatonin reduces oxidative stress and improves vascular function in pulmonary hypertensive newborn sheep
下载免费PDF全文
![点击此处可从《Journal of pineal research》网站下载免费的PDF全文](/ch/ext_images/free.gif)
Flavio Torres Alejandro González‐Candia Camilo Montt Germán Ebensperger Magdalena Chubretovic María Serón‐Ferré Roberto V. Reyes Aníbal J. Llanos Emilio A. Herrera 《Journal of pineal research》2015,58(3):362-373
Pulmonary hypertension of the newborn (PHN) constitutes a critical condition with severe cardiovascular and neurological consequences. One of its main causes is hypoxia during gestation, and thus, it is a public health concern in populations living above 2500 m. Although some mechanisms are recognized, the pathophysiological facts that lead to PHN are not fully understood, which explains the lack of an effective treatment. Oxidative stress is one of the proposed mechanisms inducing pulmonary vascular dysfunction and PHN. Therefore, we assessed whether melatonin, a potent antioxidant, improves pulmonary vascular function. Twelve newborn sheep were gestated, born, and raised at 3600 meters. At 3 days old, lambs were catheterized and daily cardiovascular measurements were recorded. Lambs were divided into two groups, one received daily vehicle as control and another received daily melatonin (1 mg/kg/d), for 8 days. At 11 days old, lung tissue and small pulmonary arteries (SPA) were collected. Melatonin decreased pulmonary pressure and resistance for the first 3 days of treatment. Further, melatonin significantly improved the vasodilator function of SPA, enhancing the endothelial‐ and muscular‐dependent pathways. This was associated with an enhanced nitric oxide‐dependent and nitric oxide independent vasodilator components and with increased nitric oxide bioavailability in lung tissue. Further, melatonin reduced the pulmonary oxidative stress markers and increased enzymatic and nonenzymatic antioxidant capacity. Finally, these effects were associated with an increase of lumen diameter and a mild decrease in the wall of the pulmonary arteries. These outcomes support the use of melatonin as an adjuvant in the treatment for PHN. 相似文献
10.