全文获取类型
收费全文 | 2409篇 |
免费 | 186篇 |
国内免费 | 13篇 |
专业分类
耳鼻咽喉 | 27篇 |
儿科学 | 77篇 |
妇产科学 | 77篇 |
基础医学 | 304篇 |
口腔科学 | 78篇 |
临床医学 | 224篇 |
内科学 | 435篇 |
皮肤病学 | 88篇 |
神经病学 | 106篇 |
特种医学 | 115篇 |
外科学 | 354篇 |
综合类 | 60篇 |
一般理论 | 2篇 |
预防医学 | 190篇 |
眼科学 | 37篇 |
药学 | 233篇 |
中国医学 | 32篇 |
肿瘤学 | 169篇 |
出版年
2023年 | 40篇 |
2022年 | 84篇 |
2021年 | 145篇 |
2020年 | 92篇 |
2019年 | 118篇 |
2018年 | 134篇 |
2017年 | 90篇 |
2016年 | 105篇 |
2015年 | 89篇 |
2014年 | 85篇 |
2013年 | 135篇 |
2012年 | 159篇 |
2011年 | 164篇 |
2010年 | 100篇 |
2009年 | 81篇 |
2008年 | 112篇 |
2007年 | 119篇 |
2006年 | 111篇 |
2005年 | 95篇 |
2004年 | 85篇 |
2003年 | 58篇 |
2002年 | 67篇 |
2001年 | 28篇 |
2000年 | 26篇 |
1999年 | 15篇 |
1998年 | 5篇 |
1997年 | 12篇 |
1996年 | 14篇 |
1995年 | 13篇 |
1994年 | 9篇 |
1993年 | 18篇 |
1992年 | 11篇 |
1991年 | 23篇 |
1990年 | 18篇 |
1989年 | 9篇 |
1988年 | 15篇 |
1987年 | 12篇 |
1986年 | 11篇 |
1985年 | 6篇 |
1984年 | 8篇 |
1981年 | 6篇 |
1980年 | 7篇 |
1979年 | 7篇 |
1974年 | 6篇 |
1973年 | 4篇 |
1971年 | 5篇 |
1970年 | 4篇 |
1969年 | 6篇 |
1967年 | 5篇 |
1966年 | 7篇 |
排序方式: 共有2608条查询结果,搜索用时 171 毫秒
1.
Fathi A Elshazly Walid K Abdelbasset Ragab K Elnaggar Sayed A Tantawy 《African health sciences》2020,20(1):368
BackgroundSecond-hand smoking or environmental tobacco smoke is a critical health risk. Children are the most vulnerable to second-hand smoking because of their small bronchial ducts, less developed immunity, and low-physical activity.ObjectivesThe purpose of this study was to ascertain the effects of second-hand smoking on lung functions in athlete and non-athlete school-aged children.MethodsThis observational study included forty-six school-aged children, their age was 8–15 years, assigned to three groups; 2 study groups and 1 control group (n=15). The study groups comprised of 16 football players, and of 15 cyclists. Lung functions were evaluated recording forced vital capacity, forced expiratory volume in 1 sec and peak expiratory flow using digital spirometer.ResultsAll measures were recorded in definite values and the children were also classified into second-hand smoking (SH), or non-exposed to tobacco smoking (NE). The findings presented a significant increase (p<0.05) of the study groups in forced vital capacity, forced expiratory volume in 1 sec and peak expiratory flow solely for the non-exposed children. However, there were non-significant differences between the cyclists and football players or between the passive smoking children and non-exposed children in any of the two study groups (p>0.05).ConclusionThe outcomes of this study suggest beneficial influences of the sports activity on the lung functions, without different influences of the cyclists and football players on the lung functions. 相似文献
2.
3.
Huda Mohammed Alkreathy Mayson H. Alkhatib Safaa Ahmed Al Musaddi Khadijah Saeed A. Balamash Nadia Nour Osman Aftab Ahmad 《Clinical and experimental pharmacology & physiology》2019,46(5):496-505
Doxorubicin (DOX) is the most commonly used anticancer drug; however, it has limited use because prolonged administration may result in severe cardiotoxicity. Simvastatin (SIM), generally prescribed for hypercholesterolaemia, has also shown salubrious results in the monotherapy or combinational drug therapy of different cancers in various models. Nanoparticle drug delivery systems are a novel way of improving therapeutics and also improving the absorption and specificity of drugs towards tumour cells. In this study, we exploited this technology to increase drug specificity and minimize imminent adverse effects. In this study, the antitumour activity of the combination formulas of DOX and SIM, either loaded in water (DOX‐SIM‐Solution) or nanoemulsions (NEs) (DOX‐SIM‐NE), was evaluated in a Swiss albino mouse model of Ehrlich ascites carcinoma. The anticancer effect was assessed by quantifying the change in body weight, mean survival time, and percent increase in lifespan (%ILS), determining haematological and serum biochemical parameters (liver function test, kidney function test and lipid profile parameters) as well as studying the histopathological alterations in liver tissues. We observed a clear increase in %ILS of the DOX‐SIM‐Solution group (265.30) that was double the %ILS of the DOX‐SIM‐NE group (134.70). However, DOX‐SIM‐NE had a non‐toxic effect on the haematological parameters, whereas DOX‐SIM‐Solution increased the levels of haemoglobin and lymphocytes. Furthermore, the encapsulation of SIM and DOX into NEs improved the levels of all serum biochemical parameters compared to the DOX‐SIM‐Solution. A reduction in the side effects of DOX‐SIM‐NE on the liver was also established using light microscopy, which revealed that the morphologies of the hepatocytes of the mice were less affected by administration of the DOX‐SIM‐NE treatment than with the DOX‐SIM‐Solution treatment. The study showed that incorporating SIM into the DOX‐loaded‐NE formulation remarkably improved its efficiency and simultaneously reduced its adverse effects. 相似文献
4.
5.
6.
S. Nour A. El-Sharkawy W. C. Burnett E. P. Horwitz 《Applied radiation and isotopes》2004,61(6):1173-1178
The objective of this work was to establish a new procedure for 228Ra determination of natural waters via preconcentration of radium on MnO2 and separation of its daughter, 228Ac, using Diphonix ion exchange resin. Following removal of potential interferences via passage through an initial Diphonix Resin column, the first daughter of 228Ra, 228Ac, is isolated by chromatographic separation via a second Diphonix column. A holding time of >30 h for 228Ac ingrowth in between the two column separations ensures secular equilibrium. Barium-133 is used as a yield tracer. Actinium-228 is eluted from the second Diphonix Resin with 5 ml 1 M 1-Hydroxyethane-1,1-diphosphonic acid (HEDPA) and quantified by addition of scintillation cocktail and LSC counting. Radium (and 133Ba) from the load and rinse solutions from the 2nd Diphonix column may be prepared for alpha spectrometry (for determination of 223Ra, 224Ra, and 226Ra) by BaSO4 microprecipitation and filtration. Decontamination tests indicate that U, Th, and Ra series nuclides do not interfere with these measurements, although high contents of 90Sr (90Y) require additional treatment for accurate measurement of 228Ra. Addition of stable Sr as a “hold back” carrier during the initial MnO2 preconcentration step was shown to remove most 90Sr interference. 相似文献
7.
8.
A young male patient with schistosomiasis and sarcoma of the urinary bladder is presented. Total cystectomy followed by radiotherapy was performed. The gross appearance, microscopic findings of the tumor and an outline of the disease are discussed. 相似文献
9.
W M Pick J E Myers A R Sayed J Dhansay R L George A W Barday 《Suid-Afrikaanse tydskrif vir geneeskunde》1990,78(1):7-10
A prevalence study of hypertension in 8 family practices in low socio-economic areas of Cape Town examined 1,046 patients over the age of 15 years. The crude prevalence rate of hypertension was 20.26%. There was no significant sex difference. Systolic pressure, diastolic pressure and hypertensive status increased with age and body mass index (BMI). There were complex relationships with regard to sex in that the female sex was predictive of hypertensive status after the age of 45 years unexplained by differences in BMI. After adjusting for age, BMI and sex differences, widowhood, poor education, obesity, a family history of hypertension or stroke and a past history of hypertension were significant predictors of hypertensive status. Smoking status, occupational social class or property ownership were not predictive. Fifty-one per cent of hypertensive subjects were treated. Of those receiving treatment, 30% were controlled resulting in a control prevalence of only 18%. Younger male subjects were better controlled by treatment. A strong need for improved diagnosis and treatment of hypertension in family practice exists in this region. 相似文献
10.
In a retrospective study of 92 patients admitted between 1975 and 1986 with anorectal malformations, we reviewed the faecal continence according to the level of their anomaly using a scoring system taken from Pescatori et al. The results of the different operative procedures were compared. Forty-seven of the 50 patients in the low anomaly group had complete faecal continence. Two died from associated anomalies and one infant had incomplete continence. This child had an associated neural tube defect. Of eight patients in the intermediate group, three had good results while two were incontinent: three patients died from associated anomalies. There were 34 patients with high anomalies, 27 of whom showed a wide range of faecal control from complete continence to different degrees of incontinence. Seven infants died from septicaemia and/or associated anomalies. The anatomical level of the lesion and the presence or absence of any associated neurological defect were the main determinants of outcome. The sex of the child and the operative procedure employed to correct the anomaly appeared to be less important. 相似文献