全文获取类型
收费全文 | 14320篇 |
免费 | 505篇 |
国内免费 | 74篇 |
专业分类
耳鼻咽喉 | 135篇 |
儿科学 | 240篇 |
妇产科学 | 123篇 |
基础医学 | 1749篇 |
口腔科学 | 384篇 |
临床医学 | 697篇 |
内科学 | 3444篇 |
皮肤病学 | 136篇 |
神经病学 | 1269篇 |
特种医学 | 594篇 |
外科学 | 2318篇 |
综合类 | 87篇 |
预防医学 | 520篇 |
眼科学 | 550篇 |
药学 | 1106篇 |
中国医学 | 76篇 |
肿瘤学 | 1471篇 |
出版年
2023年 | 40篇 |
2022年 | 94篇 |
2021年 | 176篇 |
2020年 | 110篇 |
2019年 | 131篇 |
2018年 | 178篇 |
2017年 | 130篇 |
2016年 | 207篇 |
2015年 | 216篇 |
2014年 | 293篇 |
2013年 | 439篇 |
2012年 | 741篇 |
2011年 | 839篇 |
2010年 | 454篇 |
2009年 | 395篇 |
2008年 | 764篇 |
2007年 | 907篇 |
2006年 | 951篇 |
2005年 | 1019篇 |
2004年 | 1049篇 |
2003年 | 995篇 |
2002年 | 1017篇 |
2001年 | 259篇 |
2000年 | 212篇 |
1999年 | 256篇 |
1998年 | 260篇 |
1997年 | 234篇 |
1996年 | 209篇 |
1995年 | 175篇 |
1994年 | 185篇 |
1993年 | 158篇 |
1992年 | 153篇 |
1991年 | 152篇 |
1990年 | 136篇 |
1989年 | 130篇 |
1988年 | 124篇 |
1987年 | 107篇 |
1986年 | 96篇 |
1985年 | 104篇 |
1984年 | 102篇 |
1983年 | 76篇 |
1982年 | 76篇 |
1981年 | 63篇 |
1980年 | 71篇 |
1979年 | 60篇 |
1978年 | 54篇 |
1977年 | 52篇 |
1975年 | 34篇 |
1974年 | 35篇 |
1973年 | 25篇 |
排序方式: 共有10000条查询结果,搜索用时 15 毫秒
1.
2.
3.
4.
Isolation and characterization of motile Aeromonas from human, food and environmental specimens 总被引:8,自引:0,他引:8
From July 1985 to March 1987, the occurrence of motile Aeromonas sp. in stool, food and environmental specimens was investigated to assess their pathogenic significance and to determine sources and routes of infection. A total of 9366 stool specimens were examined; Aeromonas was isolated from 11.1% of diarrhoeal stools and 2.2% of normal stools (P less than 0.001). Aeromonas counts in food specimens, which included minced beef, pork and chicken, seafood and various vegetables and their products, were unexpectedly high suggesting that infection might be food-borne rather than water-borne. About 70% of the isolates from meat products were A. hydrophila and A. sobria, while A. caviae was the most common in sea-fish, vegetables and their products. Most A. hydrophila and A. sobria strains produced haemolysin, but haemagglutinin was found more frequently in A. sobria. 相似文献
5.
Hiroshi Ujike Kazuo Tsuchida Kazufumi Akiyama Yutaka Fujiwara Shigetoshi Kuroda 《Pharmacology, biochemistry, and behavior》1995,50(4):613-617
The ontogeny of the behavioral effects of acute cocaine administration and behavioral sensitization to cocaine in rat pups was investigated. Acute behavior stimulating effects of cocaine were observed in pups as young as 7 postnatal days (PND) old, although they needed a higher dose of cocaine than adult rats to evoke the same motor effects. An adult dose-response curve pattern of stereotypy and locomotion to acute cocaine treatment was observed at PND 21, and of rearing at PND 28. Rats aged PND 7, 14, 21, 28, and 56 received repeated injections of saline or cocaine (15 mg/kg) twice a day for 5 consecutive days. After a 3-week period of abstinence, sensitization to a challenge dose of cocaine was assessed. Cocaine-induced stereotyped behavior was enhanced significantly only in rats in which cocaine pretreatment was initiated on PND 21, 28, and 56, but not earlier on PND 7 and 14. Adult female rats given repeated cocaine injections on PND 56–60 showed significantly greater sensitization than males, but no such sex difference was observed in pups given cocaine repeatedly on PND 21–25 or 28–32. These results show clearly that cocaine-induced behavioral sensitization in rats occurred only when subchronic cocaine administration was commenced on PND 21 or later. 相似文献
6.
7.
Takayoshi Ogawa Akinobu Gotoh Atsushi Takenaka Isao Hara Kazuo Gohji Soichi Arakawa Osamu Matsumoto Sadao Kamidono 《Cancer chemotherapy and pharmacology》1992,30(Z1):S66-S71
We have treated advanced transitional-cell carcinoma of the urothelial tract with methotrexate, vinblastine, Adriamycin, and cisplatin (M-VAC) chemotherapy since July of 1985. We analyzed the effect of that chemotherapy in 26 patients with advanced urothelial cancer who were treated in our hospital and followed up. They were divided into two groups. Group 1 consisted of 15 patients with distant metastases. In all, 11 of them received M-VAC as adjuvant chemotherapy for metastatic lesions after surgical removal of the primary lesion, and the remaining 4 patients were not operable since they had very advanced-stage tumors; they received only M-VAC chemotherapy. Group 2 contained 11 patients who received M-VAC neo-adjuvant chemotherapy. In group 1, the overall response rate was 57.1% and the mean duration of response was 12.6 months. In the 11 patients who had received M-VAC as adjuvant therapy after surgical removal of the primary tumor, the mean duration of response was 14.1 months. After M-VAC chemotherapy, six patients underwent surgical resection of metastatic lesions and restaging was done pathologically in these cases. The clinical response coincided with the pathological response in all six cases. In group 2,5 of 11 patients experienced histological downstaging of the resected bladder. M-VAC chemotherapy combined with surgical resection of residual tumors has proved to be an effective option against advanced urothelial cancer.Presented at the 4th International Conference on Treatment of Urinary Tract Tumors with Adriamycin/Farmorubicin, 16–17 November 1990, Osaka, Japan 相似文献
8.
Sumie Yamanaka Masanori Hashimoto Masuo Tobe Kazuo Kobayashi Jun Sekizawa Masao Nishimura 《Archives of toxicology》1990,64(4):262-268
We proposed a simple method for screening assessment of acute oral and dermal toxicity using only three rats and mice of each sex at each dose level. Animals were first treated with chemicals at a dose of 2000 mg/kg and were carefully observed for compound-related morbidity and mortality. If none of the animals died, the following toxicity tests were suspended. If some of the animals died, toxicity tests at doses of 200 and 20 mg/kg were performed. The approximate LD50 values calculated by this method showed little difference between two separate laboratories and were in good agreement with LD50 values reported in the literature. Our toxicological data also showed that LD50 values were about 2–2.5 times the MNLD (maximum non lethal dose) in acute oral and dermal toxicity. This meant that a chemical could be regarded as having an LD50 of about 4000 mg/kg or higher when there was no mortality at the dose of 2000 mg/kg. A chemical with such low toxicity would not require further testing for lethal effects. Therefore, this simple method combining the fixed-dose procedure with the limit test is suitable for determination of approximate LD50 values of chemicals and for screening for necessity for classical full LD50 test using many animals.This work was supported by a grant from Ministry of Health and Welfare in Japan (No. 467 and 511) 相似文献
9.
Nobuyuki Takemura Yasuhiko Sugawara Takuya Hashimoto Nobuhisa Akamatsu Yoji Kishi Sumihito Tamura Masatoshi Makuuchi 《Liver transplantation》2005,11(3):356-360
The incidence of hepatic venous stenosis is higher in partial liver transplantation. New methods for hepatic venous reconstruction in left liver transplantation, which secure wide anastomosis, were devised and are reported here. In the graft, the right side of the middle hepatic vein or the left side of the left hepatic vein was cut longitudinally and a rectangular-shaped vein patch was attached for venoplasty. In the recipient, after the left and middle hepatic veins were joined, the right side of the middle hepatic vein was cut toward the closed right hepatic vein, making a horizontal cavotomy for anastomosis. Of 92 patients who underwent conventional hepatic vein reconstruction, 3 were complicated by hepatic venous stenosis (median follow-up 43 months). By contrast, there were no hepatic vein complications in the 20 patients who underwent the new technique (7 months). The current method appears to be technically feasible for outflow reconstruction in left liver graft transplantation. 相似文献
10.
Jhoji Tanabe Hirohiko Nakazato Hisayoshi Tanabe Hidetoshi Hanasaki Kazuo Kawasaki Daizo Yonemura 《Documenta ophthalmologica. Advances in ophthalmology》1986,63(2):165-171
The spectral response curve (amplitude versus wavelength) of the R2 of the early receptor potential (ERP) was studied in normal, protan, and deutan subjects. The R2 amplitude peaked at 520nm in most normal subjects. The R2 at long wavelengths was smaller than normal in protans and larger than normal in deutans when the maximum amplitudes were normalized to 100% at the peak. The ratio of the R2 amplitude at 460 nm to that at 600 nm clearly differed between protans and deutans. The ERP and the rapid off-response, which is mainly due to the cessation of the late receptor potential, were recorded in the same subjects. The ratio of the sensitivity of the rapid off-response at 500 nm to that at 600 nm was correlated with the ratio of the R2 amplitude at 460 nm to that at 600nm (correlation coefficient, 0.823, p < 0.001). This study, in conjunction with our previous study, indicates that the abnormality is in the outer segments of the cones in protans and deutans. 相似文献