全文获取类型
收费全文 | 210975篇 |
免费 | 5481篇 |
国内免费 | 482篇 |
专业分类
耳鼻咽喉 | 2997篇 |
儿科学 | 7900篇 |
妇产科学 | 6310篇 |
基础医学 | 27300篇 |
口腔科学 | 7088篇 |
临床医学 | 16463篇 |
内科学 | 38735篇 |
皮肤病学 | 4842篇 |
神经病学 | 12954篇 |
特种医学 | 11137篇 |
外国民族医学 | 97篇 |
外科学 | 31464篇 |
综合类 | 1185篇 |
一般理论 | 7篇 |
预防医学 | 17958篇 |
眼科学 | 4582篇 |
药学 | 14446篇 |
2篇 | |
中国医学 | 233篇 |
肿瘤学 | 11238篇 |
出版年
2021年 | 675篇 |
2018年 | 4157篇 |
2017年 | 4309篇 |
2016年 | 3650篇 |
2015年 | 5353篇 |
2014年 | 4937篇 |
2013年 | 4130篇 |
2012年 | 10942篇 |
2011年 | 5847篇 |
2010年 | 2934篇 |
2009年 | 4384篇 |
2008年 | 2905篇 |
2007年 | 3705篇 |
2006年 | 3830篇 |
2005年 | 11860篇 |
2004年 | 13220篇 |
2003年 | 8753篇 |
2002年 | 3882篇 |
2001年 | 4745篇 |
2000年 | 2056篇 |
1999年 | 6206篇 |
1998年 | 641篇 |
1992年 | 7095篇 |
1991年 | 7311篇 |
1990年 | 7536篇 |
1989年 | 7148篇 |
1988年 | 6633篇 |
1987年 | 6397篇 |
1986年 | 6111篇 |
1985年 | 5398篇 |
1984年 | 3707篇 |
1983年 | 3001篇 |
1982年 | 1049篇 |
1981年 | 824篇 |
1980年 | 870篇 |
1979年 | 3908篇 |
1978年 | 2432篇 |
1977年 | 1822篇 |
1976年 | 1605篇 |
1975年 | 2527篇 |
1974年 | 3148篇 |
1973年 | 2794篇 |
1972年 | 2805篇 |
1971年 | 2770篇 |
1970年 | 2594篇 |
1969年 | 2499篇 |
1968年 | 2268篇 |
1967年 | 2193篇 |
1966年 | 1923篇 |
1965年 | 1141篇 |
排序方式: 共有10000条查询结果,搜索用时 62 毫秒
1.
2.
3.
4.
5.
6.
7.
Dan Azagury Tara E Mokhtari Luis Garcia Ulysses S Rosas Trit Garg Homero Rivas John Morton 《Surgery》2019,165(3):565-570
Background
Laparoscopic Roux-en-Y gastric bypass, laparoscopic sleeve gastrectomy, and laparoscopic adjustable gastric banding all lead to substantial weight loss in obese patients. Long-term weight loss can be highly variable beyond 1-year postsurgery. This study examines and compares the frequency distribution of weight loss and lack of treatment effect rates after laparoscopic Roux-en-Y gastric bypass, laparoscopic sleeve gastrectomy, and laparoscopic adjustable gastric banding.Methods
A total of 1,331 consecutive patients at a single academic institution were reviewed from a prospectively collected database. Preoperative data collected included demographics, body mass index, and percent excess weight loss. Postoperative BMI and %EWL were collected at 12, 24, and 36 months. Percent excess weight loss was analyzed by the percentiles of excess weight lost, and the distribution of percent excess weight loss was evaluated in 10% increments. Lack of a successful treatment effect was defined as <25% excess weight loss.Results
Of the 1,331 patients, 72.4% (963) underwent laparoscopic Roux-en-Y gastric bypass, 18.3% (243) laparoscopic sleeve gastrectomy, and 9.4%(125) laparoscopic adjustable gastric banding. Mean percent excess weight loss was greatest for laparoscopic Roux-en-Y gastric bypass, followed by laparoscopic sleeve gastrectomy, and then by laparoscopic adjustable gastric banding at every time point: at 2 years mean percent excess weight loss was 77.9± 24.4 for laparoscopic Roux-en-Y gastric bypass, 50.8 ± 25.8 for laparoscopic sleeve gastrectomy, and 40.8± 25.9 for laparoscopic adjustable gastric banding (P < .0001). The rates of a successful treatment effect s for laparoscopic Roux-en-Y gastric bypass, laparoscopic sleeve gastrectomy, and laparoscopic adjustable gastric banding were 0.9%, 5.2%, and 24.3% at 1 year; 0.3%, 11.1%, and 26.0% at 2 years; and 1.0%, 25.3%, and 30.2% at 3 years. At 1 year, the odds ratio of lack of a successful treatment effect of laparoscopic sleeve gastrectomy versus laparoscopic Roux-en-Y gastric bypass was 6.305 (2.125–19.08; P?=?.0004), the odds ratio for laparoscopic adjustable gastric banding versus laparoscopic Roux-en-Y gastric bypass was 36.552 (15.64–95.71; P < .0001), and the odds ratio for laparoscopic adjustable gastric banding versus laparoscopic sleeve gastrectomy was 5.791 (2.519–14.599; P < .0001). At 2 years, the odds ratio for laparoscopic sleeve gastrectomy versus laparoscopic Roux-en-Y gastric bypass increased to 70.7 (9.4–531.7; P < .0001), the odds ratio for laparoscopic adjustable gastric banding versus laparoscopic Roux-en-Y gastric bypass increased to 128.1 (16.8–974.3; P < .0001), and the odds ratio for laparoscopic adjustable gastric banding versus laparoscopic sleeve gastrectomy decreased to 1.8 (0.9–3.6; P?=?.09).Conclusion
This study emphasizes the existing variability in weight loss across bariatric procedures as well as in the lack of a treatment effect for each procedure. Although laparoscopic adjustable gastric banding has the greatest rate of a lack of a successful treatment effect, the rate remained stable over 3 years postoperatively. Laparoscopic sleeve gastrectomy showed a doubling in the rate of a lack of a successful treatment effect every year reaching 25% at year 3. The rates for lack of a successful treatment effect for laparoscopic Roux-en-Y gastric bypass remained stable at about 1% for the first 3 years postoperatively. 相似文献8.
Iclea Rocha Gama Euclides Marinho Trindade-Filho Suzana Lima Oliveira Nassib Bezerra Bueno Isabelle Tenório Melo Cyro Rego Cabral-Junior Elenita M. Barros Jaqueline A. Galvão Wanessa S. Pereira Raphaela C. Ferreira Bruna R. Domingos Terezinha da Rocha Ataide 《Metabolic brain disease》2015,30(1):93-98
9.
10.
Attachment is a behavioral and physiological system, which enables individual’s dynamic adaptation to its environment. Attachment develops in close interaction between an infant and his/her mother, plays an important role in the development of the infant’s brain, and influences the quality of interpersonal relationships throughout life.Security of attachment is believed to influence individual response to stress, exposing insecurely organized individuals to deregulated autonomic nervous system and exaggerated hypothalamic-pituitary-adrenal activity, which, in turn, produces increased and prolonged exposure to stress-hormones. Such stress responses may have considerable implications for the development of diverse health-risk conditions, such as insulin resistance and hyperlipidemia, shown by numerous studies.Although the mechanisms are not yet fully understood, there is compelling evidence highlighting the role of psychological stress in the development of type 1 diabetes (T1D). One of the possible contributing factors for the development of T1D may be the influence of attachment security on individual stress reactivity. Thus, the suggestion is that insecurely attached individuals are more prone to experience increased and prolonged influence of stress hormones and other mechanisms causing pancreatic beta-cell destruction.The present paper opens with a short overview of the field of attachment in children, the principal attachment classifications and their historic development, describes the influence of attachment security on individual stress-reactivity and the role of the latter in the development of T1D. Following is a review of recent literature on the attachment in patients with T1D with a conclusion of a proposed role of attachment organization in the etiology of T1D. 相似文献