全文获取类型
收费全文 | 3474篇 |
免费 | 171篇 |
国内免费 | 19篇 |
专业分类
耳鼻咽喉 | 17篇 |
儿科学 | 262篇 |
妇产科学 | 21篇 |
基础医学 | 267篇 |
口腔科学 | 97篇 |
临床医学 | 266篇 |
内科学 | 708篇 |
皮肤病学 | 36篇 |
神经病学 | 208篇 |
特种医学 | 99篇 |
外科学 | 832篇 |
综合类 | 89篇 |
一般理论 | 2篇 |
预防医学 | 155篇 |
眼科学 | 127篇 |
药学 | 238篇 |
中国医学 | 9篇 |
肿瘤学 | 231篇 |
出版年
2024年 | 3篇 |
2023年 | 39篇 |
2022年 | 91篇 |
2021年 | 195篇 |
2020年 | 90篇 |
2019年 | 124篇 |
2018年 | 164篇 |
2017年 | 109篇 |
2016年 | 132篇 |
2015年 | 136篇 |
2014年 | 192篇 |
2013年 | 230篇 |
2012年 | 340篇 |
2011年 | 361篇 |
2010年 | 187篇 |
2009年 | 157篇 |
2008年 | 226篇 |
2007年 | 207篇 |
2006年 | 174篇 |
2005年 | 129篇 |
2004年 | 143篇 |
2003年 | 94篇 |
2002年 | 69篇 |
2001年 | 17篇 |
2000年 | 12篇 |
1999年 | 10篇 |
1998年 | 12篇 |
1997年 | 3篇 |
1996年 | 2篇 |
1995年 | 5篇 |
1994年 | 3篇 |
1993年 | 2篇 |
1991年 | 3篇 |
1990年 | 1篇 |
1989年 | 1篇 |
1979年 | 1篇 |
排序方式: 共有3664条查询结果,搜索用时 15 毫秒
1.
2.
Ashish Chawla 《Singapore medical journal》2015,56(11):604-611
Cardiovascular and noncardiovascular conditions are commonly encountered in the emergency department. While the majority of patients have underlying cardiovascular aetiologies, such as acute myocardial infarction, congestive heart failure, aortic dissection and pulmonary embolism, a small subset of patients have underlying noncardiovascular conditions, although they present with similar symptoms of chest pain, dyspnoea, cough, haemoptysis and haematemesis. This article aims to describe the imaging findings in common noncardiovascular conditions of the chest that are frequently encountered in the emergency department, with a review of the existing literature. 相似文献
3.
Brain cyclooxygenases (COX), the rate-limiting enzyme in prostaglandin synthesis, is rapidly and transiently induced by convulsions in hippocampal and cortical neurons. Previous studies have explored the protective effect of naproxen (non-selective COX-inhibitor) or rofecoxib (selective COX-2 inhibitor) against chemical kindling in mice. With this background, the present study was designed to explore the possible effect of nimesulide (a preferential COX-2 inhibitor) against pentylenetetrazol (PTZ)-induced kindling epilepsy in mice. To induce kindling, PTZ was injected in a subconvulsive dose (40 mg/kg, i.p.) every other day for 15 days. Nimesulide (2.5 or 5 mg/kg, p.o.) was administered each day 45 min before either PTZ or vehicle challenge. The intensity of kindling was assessed immediately after PTZ administration according to a prevalidated scoring scale. On 16th day i.e. 24 h after the last dose of PTZ, animals were sacrificed and various biochemical parameters were assessed in the whole brain. Compared with normal control group, PTZ-kindled mice had significantly higher levels of malondialdehyde, nitrite, myeloperoxidase but had lower levels of reduced glutathione in the whole brain homogenate. Chronic treatment with nimesulide (2.5 or 5 mg/kg, p.o.) for 15 days showed significant decrease in kindling score and could play a role in controlling the accompanying biochemical alterations due to PTZ. These results suggested that nimesulide, a preferential COX-2 inhibitor offered neuroprotection against PTZ-induced kindling in mice. 相似文献
4.
Ashish Raj Honglei Zhang Martin R Prince Yi Wang Ramin Zabih 《Magnetic resonance in medicine》2006,55(3):649-658
Time-resolved contrast enhanced magnetic resonance angiography (MRA) may suffer from involuntary patient motion. It is noted that while MR signal change associated with motion is large in magnitude and has smooth phase variation in k-phase, signal change associated with vascular enhancement is small in magnitude and has rapid phase variation in k-space. Based upon this observation, a novel projection onto convex sets (POCS) algorithm is developed as an automatic iterative method to remove motion artifacts. The presented POCS algorithm consists of high-pass phase filtering and convex projections in both k-space and image space. Without input of detailed motion knowledge, motion effects are filtered out, while vasculature information is preserved. The proposed method can be effective for a large class of nonrigid motions, including through-plane motion. The algorithm is stable and converges quickly, usually within five iterations. A double-blind evaluation on a set of clinical MRA cases shows that a completely unsupervised version of the algorithm produces significantly better rank scores (P=0.038) when compared to angiograms produced manually by an experienced radiologist. 相似文献
5.
Sandeep Nijhawan Mukul Rastogi Ashish Joshi Atul Shende Manish Tandon Dinesh Singla Amit Mathur Subhash Nepalia Ramesh Roop Rai 《Digestive endoscopy》2007,19(2):80-82
Background: Ingestion of coins is a common clinical problem in children. Many of the coins are ferromagnetic and can be retrieved with the help of a magnet. We describe the use of a novel endoscopic accessory for removing ferromagnetic coins. Material and methods: Two magnet discs of 1.5 cm diameter were joined to a 200 cm steel wire of 0.75 mm thickness with a terminal 5 cm spring. A Teflon tube (160 cm, 7 F) was used along with this instrument as a sleeve. The use of this accessory was analyzed prospectively in subjects presenting with a history of coin ingestion. The time taken for removal of coins, complications during the procedure and failure rate was noted. Effect of the magnet on cardiac rhythm was also noted during the procedure. Results: A total of 55 children (mean age 5.1 ± 2.3 years) with coin ingestion presented over a period of 1 year. Forty‐four coins were ferromagnetic. All ferromagnetic coins were removed successfully. Mean time for removal was 68 ± 22 s. No complications were encountered. Conclusion: The novel magnetic instrument is precise, safe and quick for the removal of ferromagnetic coins under direct vision. 相似文献
6.
7.
8.
9.
Parmar RC Bavdekar SB Bansal S Doraiswamy A Khambadkone S 《Journal of postgraduate medicine》2000,46(2):91-93
Scleredema adultorum is a rare connective tissue disorder reported usually following streptococcal infection, influenza, measles, and mumps. It has been reported occasionally following trauma and tuberculous lymphadenitis. This is a report of scleredema adultorum developing after chicken pox in an eight-year-old male child. The diagnosis was established by characteristic picture on skin biopsy using special stain. The patient had a benign course and a spontaneous recovery in two weeks. The case has been reported as the first case of scleredema adultorum developing after chicken pox. 相似文献
10.
Enteric fever is a common infectious disease of the tropical world, about 80% of these cases occur in Asian countries. Enteric fever presenting with isolated cerebellar ataxia or nephritis is rare. We report three cases of enteric fever that presented with these complications. Isolated cerebellar ataxia usually occurs in the second week, whereas in our cases it presented within first four days of fever. The common complications of enteric fever related to the urinary tract are cystitis, pyelitis, and pyelonephritis. Glomerulonephritis is uncommon. Most patients with enteric glomerulonephritis present with acute renal failure, hypertensive encephalopathy, or nephritic syndrome. In comparison, our case had milder manifestations. All three patients were treated with parenteral ceftriaxone and showed a prompt recovery. 相似文献