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1.
Vilma Liaugaudaite Naomi A. Fineberg Aurelija Podlipskyte Julija Gecaite Alicja Juskiene Narseta Mickuviene 《International journal of psychiatry in clinical practice》2020,24(2):116-119
AbstractObjective: This study aims at identifying associations between cognitive function and suicidal ideation in the sample of patients with anxiety and mood disorders (AMD).Methods: In sum, 186 (age = 39?±?12.3 years; 142 [76.3%] females) patients with AMD were enrolled in the study. Assessment included evaluation of socio-demographic information, medication use, anxiety and depression symptoms. Cognitive tests included measures of psychomotor performance and incidental learning using the Digit Symbol Test. Trail Making Tests respectively measured perceptual speed, task-switching and executive control. Additionally, 21 patients completed tests from the Cambridge Automated Neuropsychological Test Battery measuring set shifting (Interdimensional/extradimensional set-shift), executive planning (Stockings of Cambridge), and decision making (Cambridge Gamble Task [CGT]).Results: Almost half (45.0%, n?=?86) of the study sample patients had experienced suicidal ideations. In multivariable regression analysis, suicidal ideation was associated with a greater overall proportion of bet and risk taking on the CGT task (β?=?0.726, p?=?.010 and β?=?0.634, p?=?.019), when controlling for socio-demographic characteristics, medication use, anxiety and depression symptoms.Conclusions: Outpatients with AMD and suicidal ideation could be distinguished by the presence of cognitive deficits in the executive function domain, particularly in impulse-control and risk taking. 相似文献
2.
Bień Agnieszka Rzońca Ewa Zarajczyk Marta Wilkosz Katarzyna Wdowiak Artur Iwanowicz-Palus Grażyna 《Quality of life research》2020,29(10):2669-2677
Quality of Life Research - The aim of the study was to assess QoL and identify and analyse its determinants in women with endometriosis. The study was performed in 2019 in health centres in Lublin... 相似文献
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Inflammation but not obesity or insulin resistance is associated with increased plasma fibroblast growth factor 23 concentration in the elderly 下载免费PDF全文
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Grazyna Bednarek-Tupikowska Alicja Filus Justyna Kuliczkowska-P?aksej Krzysztof Tupikowski Anna Bohdanowicz-Pawlak Andrzej Milewicz 《Gynecological endocrinology》2006,22(4):207-212
AIM: The aim of the present study was to investigate the influence of endogenous estradiol and estrogen and estrogen-progestin therapies on concentration in pre- and postmenopausal women. MATERIALS AND METHODS: The study groups consisted of 26 women with surgical menopause (mean+/-standard deviation (SD): age 51.8+/-2.6 years, body mass index (BMI) 26.45+/-4.56 kg/m(2)), 54 with natural menopause (mean+/-SD: age 50.5+/-3.0 years, BMI 25.75+/-4.09 kg/m(2)) and 40 premenopausal controls (mean+/-SD: age 48.3+/-2.3 years, BMI 26.23+/-4.12 kg/m(2)). The group with surgical menopause received estradiol transdermally (50 microg/day) and those with natural menopause received additionally medroxyprogesterone acetate (5 mg/day) for the last 12 days of the cycle. Before and after 4 months of therapy, body weight, waist and hip circumferences and blood pressure were measured, and BMI and waist-to-hip ratio (WHR) were calculated. Serum leptin, follicle-stimulating hormone (FSH), estradiol (E(2)), testosterone, prolactin and dehydroepiandrosterone sulfate (DHEAS) were measured prior to and after treatment. RESULTS: Leptin concentrations did not differ statistically among the groups. No correlations between leptin and E(2), FSH, prolactin, testosterone and DHEAS concentrations were found in any of the groups before and after treatment. Leptin level correlated positively with body mass, BMI and hip and waist circumferences in all groups. There were no correlations between leptin and WHR in the pre- and postmenopausal groups. In the premenopausal group and in some postmenopausal groups, serum leptin level correlated with blood pressure. CONCLUSIONS: Endogenous E(2) and androgens in premenopausal women and estrogen and estrogen-progestin therapies in postmenopausal subjects do not influence serum leptin concentrations. Leptin level is related to body mass and BMI, but not to sex hormone status. The distribution of adipose tissue and the type of obesity (android or gynoid) have no influence on serum leptin concentration. The correlation between serum leptin level and blood pressure requires further investigation. 相似文献
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Anna Krygowska-Wajs William P. Cheshire Zbigniew K. Wszolek Alicja Hubalewska-Dydejczyk Barbara Jasinska-Myga Matthew J. Farrer Marek Moskala Anna Sowa-Staszczak 《Parkinsonism & related disorders》2009,15(9):692-696
ObjectiveTo assess for the presence of gastric dysmotility in familial and sporadic Parkinson disease (PD).Methods10 subjects with familial Parkinson disease (fPD), 35 subjects with sporadic Parkinson disease (sPD), and 15 controls, all from academic tertiary care movement disorders centers, were studied. fPD was defined as the presence of at least 2 affected individuals within 2–3 consecutive generations in a family. Molecular genetic analysis has not revealed, thus far, any known genomic abnormality in these families. Gastric emptying was assessed by dynamic abdominal scintigraphy over 92 min following ingestion of a solid meal containing 99mTc-labeled colloid of 40 MBq activity. The main outcome measures were gastric emptying half-time and radiotracer activity over the gastric area at 46 and at 92 min.ResultsGastric emptying time was delayed in 60% of subjects with PD. In comparison to mean t1/2 of 38 ± 7 min in controls, mean t1/2 was 58 ± 25 min in fPD (p = 0.02) and 46 ± 25 min in sPD (p = 0.10). Both fPD and sPD groups included subjects with delayed gastric emptying at an early stage of disease.ConclusionsPatients with fPD showed significantly delayed gastric emptying in comparison to normal age-matched individuals. Further studies of gastrointestinal dysfunction in PD, particularly fPD, are warranted. 相似文献
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Jerzy Toborek Zbigniew Gajda Alicja Balin 《Chirurgia narzadów ruchu i ortopedia polska》2005,70(2):115-118
The results of bacteriological tests of Palacos R cement with antibiotic 4 days, 7 days, 2 weeks, 3 weeks and 4 weeks after implantation in rabbit organism have been presented in this work. The results of tests of mechanical characteristics of cement with and without antibiotic samples after being kept in physiological saline for 3 to 6 weeks have also been discussed. Bacteriological tests prove that antibiotic (III generation cephalosporin) added to surgical cement retain its bacteriostatic properties. When tested on rabbits cement plus antibiotic retains its bacteriostatic properties after 4 weeks period. It has state, that by reason of prolonged time of activity antibiotic into surgical cement, it is necessary to investigate the mechanical characteristics of cement conditioned in physiological saline for 3 months at least. 相似文献
9.
Bernard Stuart Declan Fox Harry Murphy Bryan Lynch J. Loftus E. Naughten I. Saul O. Sheil N. Duignan A. Jackson W. A. Gorman G. Fox T. Matthews T. Clarke Mark M. Reid H. L. Halliday B. G. McClure P. S. Thomas Michael O’Dowd Michael J. O’Dowd Kevin Connolly F. Leahy Dr. R. G. White Ruth Connolly Colm O’Herlihy Alicja Radic Dr. 《Irish journal of medical science》1986,155(6):209-212
10.
Johanna Albert Leif Kindlund Barbro Nilvér Waldemar Gożdzik 《Central European Journal of Medicine》2006,1(2):162-171
Abstract: Background: The laryngeal mask airway (LMA) can be used in general anaesthesia without neuromuscular block. The
laryngeal tube (LT) is a new airway device with similar airway features as LMA. LT is provided with a distal cuff to prevent
regurgitation. In this study we compared the LMA and LT concerning patient and user aspects.
Methods: Sixty patients with ASA (American Society of Anestesiologists) score 1–2 scheduled for minor surgery were randomized
to be ventilated either through LMA or LT. After insertion, the number of insertion attempts, and “positioning” and “airway-assessment”
was evaluated. The patients reported on “sore throat” after 30 and 60 minutes and the day after anaesthesia.
Results: Gender and mean age were equal in both groups. The first insertion attempt was successful in 25 of 28 patients randomised
to LMA and in 23 of 27 patients randomised to LT. LMA was evaluated to be easier in “positioning” whereas no difference in
“sore throat” was reported.
Conclusion: We found no difference between the LMA and the LT in terms user and patient friendliness and safety. 相似文献