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BackgroundThe optimal management of community acquired pneumonia (CAP) depends on the clinical and microbiological profile in the locality.ObjectivesTo determine the clinical and microbiological profile of patients admitted with CAP in Ilorin, Nigeria.MethodsOne hundred and two consenting consecutively selected patients with clinical and radiologic confirmation of CAP were recruited in 12 months. The socio-demographic, physical examination and laboratory/radiologic parameters were documented in a questionnaire. Microbiological evaluation of their sputum was done and blood samples were taken for complete blood count, culture, serum urea and serological evaluation for atypical bacteria and some viral pathogens.ResultsCAP constituted 5.9% of the total medical admissions during the one-year study period. The mean age of the patients was 49 ± 22 years with the largest frequency in those aged 65 years and above. The commonest symptoms were shortness of breath (96.1%) and cough (94.1%), with a median duration of 3 days from symptom onset to admission. Systemic hypertension was the commonest comorbid illness (25/102; 24.5%). Klebsiella pneumoniae was the predominant pathogen isolated (20/102; 28.1%). The susceptible antibiotics were Imipenem, Ceftazidime and Ceftriaxone. Intra-hospital mortality was 17.6%. CURB – 65 score of ≥ 2 and the presence of complications of CAP were the independent predictors of mortality.ConclusionCAP constitutes a significant disease burden in Ilorin, Nigeria. Typical bacteria accounted for over half of the pathogens isolated from the patients with gram negative agents predominating. This highlights a possible shift in the microbiological profile which could guide empirical treatment.  相似文献   
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The differences in the maternal and child health care services offered by government and private sector in Abha and Khamis Mushayt cities in Asir Region of Saudi Arabia were compared. Self administered questionnaires and observation sheet were used for the study. It was found that the government clinics were more involved in the running of under 5 clinics and giving health education to patients. The private clinics took more care of women general health care but lacked the continuous domiciliary visit to pregnant women. The catchment area which served the government PHCCs made accessibility to service easier to government patients and this was thought to be the reason why government patients kept regular appointments. On the other hand, private patients who have the freedom to choose where they get service have been found to be irregular in keeping clinic appointment. It was suggested that there should be geographical spread in the location of private clinics to facilitate accessibility and that the health education and under 5 clinics should be well incorporated into the services offered by private clinics.  相似文献   
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The Expanded Programme of Immunization in Ondo State, Nigeria, which began in 1978 has been reviewed. Non-availability of constant electrical supply needed to keep vaccine at their original potency, shortage of trained health manpower, administrative shortcomings and lack of proper health education have been identified as some of the factors hindering effective implementation of the programme.  相似文献   
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