全文获取类型
收费全文 | 3318篇 |
免费 | 162篇 |
国内免费 | 11篇 |
专业分类
耳鼻咽喉 | 13篇 |
儿科学 | 90篇 |
妇产科学 | 39篇 |
基础医学 | 287篇 |
口腔科学 | 70篇 |
临床医学 | 233篇 |
内科学 | 937篇 |
皮肤病学 | 32篇 |
神经病学 | 334篇 |
特种医学 | 119篇 |
外科学 | 651篇 |
综合类 | 19篇 |
预防医学 | 99篇 |
眼科学 | 59篇 |
药学 | 198篇 |
中国医学 | 26篇 |
肿瘤学 | 285篇 |
出版年
2023年 | 16篇 |
2022年 | 33篇 |
2021年 | 66篇 |
2020年 | 54篇 |
2019年 | 67篇 |
2018年 | 74篇 |
2017年 | 45篇 |
2016年 | 72篇 |
2015年 | 87篇 |
2014年 | 99篇 |
2013年 | 129篇 |
2012年 | 173篇 |
2011年 | 196篇 |
2010年 | 109篇 |
2009年 | 76篇 |
2008年 | 175篇 |
2007年 | 197篇 |
2006年 | 179篇 |
2005年 | 173篇 |
2004年 | 176篇 |
2003年 | 152篇 |
2002年 | 188篇 |
2001年 | 102篇 |
2000年 | 80篇 |
1999年 | 78篇 |
1998年 | 39篇 |
1997年 | 30篇 |
1996年 | 30篇 |
1995年 | 21篇 |
1994年 | 28篇 |
1993年 | 15篇 |
1992年 | 56篇 |
1991年 | 59篇 |
1990年 | 40篇 |
1989年 | 43篇 |
1988年 | 32篇 |
1987年 | 40篇 |
1986年 | 29篇 |
1985年 | 27篇 |
1984年 | 17篇 |
1983年 | 12篇 |
1982年 | 12篇 |
1979年 | 15篇 |
1974年 | 15篇 |
1972年 | 9篇 |
1970年 | 13篇 |
1969年 | 12篇 |
1968年 | 11篇 |
1967年 | 12篇 |
1965年 | 9篇 |
排序方式: 共有3491条查询结果,搜索用时 15 毫秒
1.
T Sasai S Sakakibara M Kaji T Nitta Y Masaki T Yajima M Gomibuchi S Tanaka T Shouji 《Kyobu geka. The Japanese journal of thoracic surgery》1991,44(2):132-134
Post-thoracotomy wound pain in 11 patients who underwent thoracic operation was controlled by intercostal nerve block with alcohol and thoracic epidural anesthesia. The intercostal nerve block was performed just before the closure of the thoracotomy wound. Epidural anesthesia was employed from the 1st to 5th post operative day. This method alleviated post-thoracotomy pain and obviated postoperative pulmonary complication in all patients in early post operative periods. In late post operative periods after discharge, intercostal nerve block could maintain excellent analgesia in 9 of 11 patients, only 2 patients required analgesic drugs or re-block of the intercostal nerve. Thus, intercostal nerve block with alcohol is an effective and simple option to control recalcitrant post-thoracotomy wound pain in thoracic surgery. 相似文献
2.
3.
FR900403, a new antifungal antibiotic produced by a Kernia sp 总被引:3,自引:0,他引:3
T Iwamoto A Fujie Y Tsurumi K Nitta S Hashimoto M Okuhara 《The Journal of antibiotics》1990,43(9):1183-1185
4.
Epidemiological studies of air pollution and health effects in areas near roadways with heavy traffic in Tokyo] 总被引:2,自引:0,他引:2
M Ono M Murakami H Nitta S Nakai K Maeda 《[Nihon kōshū eisei zasshi] Japanese journal of public health》1990,37(5):321-332
Recent concern regarding health effects of air pollution in Japan has concentrated mainly on traffic-induced air pollution and its health effects in large cities. In Japan, where many people in large cities have been living near major roadways, the increase of automobile exhaust due to heavy traffic congestion will predictably cause a greater impact on people living near major roadways. We surveyed the characterization of residential suspended particulate matter (SPM) and nitrogen dioxide (NO2) concentrations along the major roadways in Tokyo, along with a health survey on the respiratory conditions of residents living in the same area, to examine the relationships between indoor pollutant levels, prevalence of respiratory symptoms and distance from roadways. The environmental monitoring was conducted in five phases. Using a newly developed SPM sampler and NO2 filter badge, continuous 4 day (96 hours) measurements were conducted in two hundred residential homes for four weeks. NO2 was measured in the living room, kitchen and outside of each home, while SPM was monitored in the living room. Health information was collected in October 1987 using ATS-DLD self-administered questionnaires. Of the 1,093 homes investigated, responses from 805 homes were received. The following results were obtained. SPM and NO2 concentrations showed large variations. Indoor pollution levels mostly depended on indoor sources, i.e. cigarette smoking and unventilated space heaters, and the effects of those indoor sources were influenced by the building structure with respect to air tightness. An association between increase in pollutant levels and the distance from the roadway was observed. However its effect is small compared to indoor source effects. The prevalence rate of respiratory symptoms was higher in those areas nearest roadways with heavy traffic both in children and adults. These results suggest the presence of a relationship between automobile exhaust and health effects. 相似文献
5.
6.
Seijiro Yoshida Yoshio Nitta Katsuhiko Oda 《The Japanese Journal of Thoracic and Cardiovascular Surgery》2005,53(4):230-233
A 65-year-old patient with ischemic heart disease and severe diabetes mellitus underwent minimally invasive direct coronary
artery bypass grafting under general combined with epidural anesthesia. Paraplegia developed after surgery and the diagnosis
of anterior spinal artery syndrome was made based on the patient s neurological condition and magnetic resonance imaging findings.
Paraplegia following epidural anesthesia is a rare but recognized complication and this complication should be taken into
account, especially in patients at risk, when considering epidural analgesia techniques in the minimally invasive cardiac
surgery. 相似文献
7.
Yasuhiko Tamada Kikuka Yokochi Yoshimi Oshitani Yukiko Nitta Toshihiko Ikeya Kazuo Hara Katsushi Owaribe 《The Journal of dermatology》1995,22(3):201-204
We report a 73-year-old woman with typical clinical, histological and immunofluorescence features of pemphigoid nodularis. Direct immunofluorescence studies of prurigo nodularis-like lesions and peribullous skin showed the linear deposition of IgG and C3 at the basement membrane zone. Circulating IgG against the basement membrane was also detected by indirect immunofluorescence. The serum from the patient was shown to contain the autoantibody against 230 kDa hemidesmosomal antigen associated with bullous pemphigoid antigen. 相似文献
8.
9.
Mitsuko Suehiro Minoru Fukuchi Masatoshi Kohsaki Yoshinobu Takemoto Akihisa Kanamaru Eizo Kakishita 《Annals of nuclear medicine》1992,6(2):79-82
We measured serum thymidine kinase (TK) activity with a radioenzyme assay system employing [I-125]-iododeoxyuridine as the tracer on serial specimens from five bone marrow transplant (BMT) patients before and after transplantation. The serum level of TK activity in the 4 patients with effective BMT treatment ranged from 3.0 to 16.9 U/L (mean, 7.80 U/L) before transplantation and from 27.3 to 236.1 U/L (mean, 82.95 U/L) after the BMT treatment. Mean serum TK activity increased 13.17-fold (range, 1.68 to 29.14-fold). In contrast, the activity in the patient with ineffective BMT treatment was not significantly different during, before, or after BMT treatment. In addition, serum TK activity in BMT patients was well correlated with the change in the number of leukocytes before and after BMT treatment [r = +0.709 (p less than 0.01), y = 0.012 x +0.87]. We conclude that the determination of serum TK activity in BMT patients is very useful in monitoring the course of bone marrow transplantation in the early recovery phase. 相似文献
10.
Akihisa Okumura Ikuya Tsuge Tetsuo Kubota Hirokazu Kurahashi Jun Natsume Tamiko Negoro Kazuyoshi Watanabe 《European journal of paediatric neurology》2007,11(6):385-388
We evaluated drug-specific T cell responses in a patient with refractory partial seizures and paroxysmal kinesigenic choreoathetosis successfully treated with clinical desensitization to phenytoin. Drug-induced lymphocyte transformation test before desensitization was negative with a stimulation index of 130%. The frequencies and cytokine-producing phenotypes of phenytoin-specific T cells were examined simultaneously by using a carboxyfluorescein succinimidyl ester (CFSE) dilution assay. Before desensitization, the proportion of CFSElow CD4+ cells in whole CD4+ was 3.09%; 13.6% of CFSElow CD4+ cells were stained with anti-interferon gamma antibody. After desensitization, phenytoin-specific CFSElow CD4+ cells decreased to background level. These results indicate that CFSE dilution assay will be useful for the diagnosis and monitoring of drug hypersensitivity. 相似文献