���ٿ������Ӧ����θ���������Ի������߹���Ӱ��Meta����

??Influence of enhanced recovery after surgery for radical resection of gastric cancer on immune function??a Meta-analysis WANG Xiang-an, YU Li-ming, FAN Ji-chang, et al. Department of Gastrointestinal Surgery, the Second Affiliated Hospital, Nanchang University, Nanchang 330006, China
Corresponding author??YANG Gang, E-mail??ygrealtom@sohu.com
Abstract Objective To evaluate the influence of enhanced recovery after surgery (ERAS) for radical resection of gastric cancer on immune function. Methods The major domestic and foreign databases were searched to collect the literatures of randomized controlled trial (RCT) about the the comparison of ERAS and conventional perioperative care in radical resection of gastric cancer published by December, 2014 in both Chinese and English. After screening for inclusion, quality assessment and data extraction, Meta-analysis was conducted by the Review Manager 5.2 software. Results Sixteen studies involving 1101 patients were selected finally, with 563 patients in ERAS group and 538 patients in control group. Results of Meta-analysis showed that the levels of IL-6 on postoperative day (POD) 1, 3 and TNF- α on POD3 and CRP on POD1, 3, 7 in ERAS group were lower than those in control group significantly (all P<0.05) . Those on the rest of the days showed no significant difference (all P>0.05). The levels of IgA on POD1, 3, 7 and IgG on POD3, 6, 7 in ERAS group were higher than those in control group significantly (all P<0.05). But, the levels of IgM on POD1, 3, 7 showed no significant difference between the two groups (all P>0.05) . Conclusion ERAS for radical resection of gastric cancer can decrease the inflammatory responses and preserve immune function of bodys compared with conventional perioperative care.     

��ֱ������ת�Ƶ�΢������������

??Minimally invasive interventional therapy of colorectal liver metastases ZHANG Hang-yu, ZHU Xu, GUO Jian-hai. Department of Interventional Therapy, Peking University School of Oncology, Beijing Cancer Hospital & Institute; Key Laboratory of Carcinogenesis and Translational Research (Ministry of Education), Beijing 100142, China
Corresponding author:ZHU Xu,E-mail:drzhuxu@163.com
Abstract Compared with systemic chemotherapy and surgery, minimally invasive interventional therapy has the advantages of repeatable, minimally invasive and high local control rate. With the development of technology and the update of clinical evidence, minimally invasive interventional therapy in the multidisciplinary team (MDT) has gain more acceptance.For the tumor feeding artery administration, interventional treatment via the vascular as a second-line treatment after systemic treatment failure has been recommended by the Guide. It can not only improve the tumor local control effect, but also reduce the toxicity of chemotherapy drugs. Non vascular minimally invasive treatment as a necessary complement to the comprehensive treatment of colorectal liver metastases, the reasonable choice of indications can obtain unparalleled curative effect compared with systemic chemotherapy and surgery. However , systemic treatment must be considered when making the choice of the local treatment methods.     

健脾益气通络法治疗糖尿病周围神经病变24例临床观察

目的观察健脾益气通络法治疗糖尿病周围神经病变的临床疗效。方法将48例糖尿病并发周围神经病变患者按随机数表随机分为两组，治疗组24例。给予健脾益气通络中药汤剂口服治疗；对照组24例给予肌注腺苷钴胺针剂，疗程均为4周。观察期间两组均正规降糖治疗。结果健脾益气通络法治疗糖尿病周围神经病变24例，其临床证候总有效率为83．3％，明显高于对照组的37．5％，经统计学处理，差异有非常显著性（P〈0．01）。治疗后治疗组振动觉阈值有效率为75．0％，也明显高于对照组的33．3％，经统计学处理，差异有非常显著性（P〈0．01）。结论健脾益气通络法对糖尿病周围神经病变有较好的治疗作用。     

西红花苷对血管内皮细胞的保护作用研究

目的 研究西红花苷对过氧化氢所致牛内皮细胞（BAEC）损伤的保护作用，并初步探讨其可能的作用机制。方法 利用过氧化氢刺激BAEC，观察了西红苷对细胞培养液内MDA、SOD、LDH含量或活性的影响，并对细胞进行流式细胞分析和细胞内钙测定，观察了该药对细胞凋亡及胞内钙的影响。结果 西红花苷可剂量依赖性的减少MDA生成，提高SOD活性，阻止LDH的外漏，还能抑制过氧化氢所致细胞内钙升高，减少细胞凋亡百分率。结论 西红花苷对过氧化氢所致BAEC损伤有保护作用，其作用机制可能与其拮抗细胞内钙有关，值得在临床上推广应用治疗心血管疾病。     

1011例农村农药中毒分析

随着农村生产责任制的实行,出现了自购、自存、自用农药的新情况,使农药的使用量和接触人数增多,农药中毒不断发生。本文对我区1011例农药中毒事故进行分析,探讨农药中毒发生的规律,为制定防治措施提供科学依据。现报道如下: 一、材料和方法材料取自成都市的温江、蒲江、灌县、新津、新都、大邑、崇庆、邛崃、郫县、彭县等十县1986年(全年)农药中毒报告卡,进行相应的统计学处理。     

对伴有心律失常者施行扁桃体摘除术的体会：附14例报告

本文报告14例室性心律失常者施行扁桃体摘除术,结果13例顺利摘除并纠正了心律失常,改善了全身状况;另1例因手术刺激并室速而中止手术,无并发症。作者认为对伴有心律失常的扁桃体炎患者,应尽早积极地采取手术治疗。     

瘘口周围皮瓣Y—V成形尿道瘘修补术

瘘口周围皮瓣ＹＶ成形尿道瘘修补术罗汉宏何恢绪李清荣聂海波吕军曹启友１９８８年８月至１９９６年３月，对２１例尿道下裂尿道成形术后尿瘘患者施行瘘口周围皮瓣ＹＶ成形尿瘘修补术，２０例一次成功。报告如下。临床资料本组２１例，年龄１～２３岁，平均１１３岁...     

新疆维吾尔族成人颅底和蝶鞍X线测量

作者根据Ｘ线诊断测量标准，观察测量维吾尔族健康成人７６例，对照组汉族１０１例Ｘ线头颅正侧位片的颅底和蝶鞍１６例指标；并进行计算分析，与其它资料进行比较。