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近20年由于免疫学、细胞化学等的重大进展,肾活检、荧光技术和电镜的普遍应用,人们对肾小球疾病的病因学和发病学有了较明确的认识。本文着重综述肾小球疾病发病机理若干问题。一、肾小球疾病非免疫性发病机理最近不少学者报道了有关非免疫性肾小球损伤的发病机理在发病学上的重要作用。Baldwin认为肾小球进行性损伤是受多种非免疫因素的影响。 1.肾内血管病变作者认为肾内血管病变可能为肾小球疾病的原发因素。 Kincaid-Smith报道在40岁以下,血压在 相似文献
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目的了解孕妇的口腔健康知识、态度及行为现状,评价其健康教育的干预效果,为制定孕期及孕前口腔健康教育策略提供依据。方法在上海市某区级妇幼保健院整群抽取处于孕中期的妇女共300人。在干预前使用自行设计的调查问卷对调查对象进行口腔健康知识、态度及行为状况的基线调查。在孕妇常规的产前健康教育课程中加入20 min有关口腔健康知识的内容,并于课后进行快速效果评估。在2个月后对同一人群进行随访,了解其口腔保健行为的改变情况。结果干预后,孕妇的各项口腔健康知识知晓率均有了显著提高,知识总平均分从干预前的63.48分上升到86.03分,及格率为从63.09%上升到91.6%;刷牙方式、时间、饭后漱口、及时进行口腔检查等多项健康行为形成率均有显著提高。多因素分析结果显示,孕妇本人的文化程度及其配偶的文化程度是影响孕妇口腔健康知识水平的主要因素。结论产前口腔健康教育干预可显著提高孕妇口腔健康的知信行水平,倡议将孕期口腔健康教育列为围产期保健及牙病防治的重点项目,探索产科及口腔科跨部门合作的孕期口腔教育模式。 相似文献
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Chen Nan-ming陈南明 Yin Dong-ping阴东平 Feng Ming-li冯明利 and Yuan Ju-ping袁菊平Department of Internal Medicine Nanjing Railway Medical. College Nanjing 《中华医学杂志(英文版)》1986,99(1):75-80
The purpose of this study is twofold. First, a
simple method of measuring urine PCO2, P02 and
pH is recommended. Second, the changes of urine
gases in normal individuals after broad bean meal
and patients with acute renal failure are measured
by this method. The method is practicable as the
results obtained are similar to those of the controls.
The study was performed by oral test without
substantial extracellular fluid volume expansion
(i.e. under ordinary living conditions). It revealed
that urine pH was usually increased to some extent
after broad bean meal in normal persons, especially
in the young and middle-aged. The urinary minus
blood (U-B) PC02 gradient was elevated in about
90% of those with urine pH above 6.0. The amount
of urine C02 iS equivalent to that needed in sub-
clinical metabolism. In addition, there was an in-
verse correlation (r= -0.68) between urinary P02 and
urinary PC02. Factors affecting urinary P02 were
multiple.
Urine gases are highly sensitive to acute renal
failure and change with the variations in renal func-
tion during the entire course of the disease.
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