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排序方式: 共有33条查询结果,搜索用时 15 毫秒
1.
The impact of hydrosalpinx (HSPX) on in-vitro fertilization (IVF) outcome
has recently been the subject of intense debate. Most, but not all, studies
have reported decreased implantation and pregnancy rates and increased
early pregnancy loss in HSPX patients. This has led to prophylactic
salpingectomies prior to IVF in HSPX patients despite the lack of any
prospective studies to suggest that any improvement will occur. Women with
HSPX constitute a heterogeneous population because some conceive easily
with IVF while others do not until after surgical correction. HSPX also
increases in size with ovarian stimulation, and can cause implantation
failure by fluid reflux into the uterine cavity. Careful assessment of the
endometrial lining is mandatory in HSPX to rule out fluid reflux from the
HSPX. We present two case reports of patients whose HSPX enlarged with
ovarian stimulation, causing fluid reflux into the uterine cavity which was
only noted after human chorionic gonadotrophin (HCG) administration.
相似文献
2.
The glyoxylate cycle, which is well characterized in higher plants and some microorganisms but not in vertebrates, is able
to bypass the citric acid cycle to achieve fat-to-carbohydrate interconversion. In this context, the hydrodynamic transfer
of two glyoxylate cycle enzymes, such as isocytrate lyase (ICL) and malate synthase (MS), could accomplish the shift of using
fat for the synthesis of glucose. Therefore, 20 mice weighing 23.37 ± 0.96 g were hydrodinamically gene transferred by administering
into the tail vein a bolus with ICL and MS. After 36 hours, body weight, plasma glucose, respiratory quotient and energy expenditure
were measured. The respiratory quotient was increased by gene transfer, which suggests that a higher carbohydrate/lipid ratio
is oxidized in such animals. This application could help, if adequate protocols are designed, to induce fat utilization for
glucose synthesis, which might be eventually useful to reduce body fat depots in situations of obesity and diabetes. 相似文献
3.
Prof. Dr. C. Burri FI. Henkemeyer Th. Rüedi 《Langenbeck's archives of surgery / Deutsche Gesellschaft fur Chirurgie》1971,330(1):54-78
Zusammenfassung Die unhappy triad der Knochenchirurgie, Infekt, Defekt und Instabilität stellt uns auch heute noch vor schwer zu lösende Probleme. Das Vorgehen der Wahl scheint uns die Stabilisierung der Fragmente mittels einer internen (Osteosynthese) oder externen (äußere Spanner) Fixation, die radikale Ausräumung des Herdes, die vorübergehende Spüldrainage nach Willenegger [26, 27, 28] und schließlich das Auffüllen des Defektes mit autologer Spongiosa zu sein. Bei allen unseren in dieser Studie erfaßten 25 Patienten kam es zum knöcherner Einbau des Transplantates und Abheilung des Haut- und Weichteildefektes, bei vier Patienten be schleunigte eine Spalthautverpflanzung die Heilung. 23 Fälle sind 1 bis 6 Jahre nach der Behandlung vom Infekt her rezidivfrei geblieben, bei sämtlichen Patienten konnte die Belastungsstabilität erreicht werden.Durch das beschriebene Vorgehen konnte in allen Fällen die Gelenkfunktion erhalten oder verbessert werden. Das aktive Eingreifen gestattet zudem Achsen- und Längenkorrekturen.Klinische, szintigraphische und histologische Untersuchungen zeigen, daß der Einbau des spongiösen Transplantates unmittelbar nach der Verpflanzung einsetzt und nach 3 Monaten soweit fortgeschritten ist, daß die Belastungsstabilität erreicht wird.
Autogenous cancellous bone in osteomyelitis with defects of bone, soft tissue and skin
Summary Surgeons are still confronted with the grave problem of the unhappy triad of bone surgery, i.e. infection, osseous defect and instability. To us the stabilisation of fragments by means of internal or external fixation, the radical saucerization and packing of the cavity with autogenous cancellous bone with preceding irrigation drainage seems to be the procedure best suitable. 25 patients with infected defects of bone, soft tissue and skin were treated accordingly and followed up 1 to 6 years later: In all cases the graft had been integrated and the skin- and soft tissue defects had healed. In 23 cases osteomyelitis had not re-occured, weight bearing stability had been achieved in all 25 cases.The described procedure had either maintained or even improved articular function. Additionally the active intervention allowes correction of axis and length.It is demonstrated by radiological, scintigraphical and histological examinations, that the integration of the cancellous bone transplant begins immediately after transplantation and is advanced within three months to such a point that weight bearing becomes possible.相似文献
4.
Postinflammatory ossicular fixation is a common problem encountered by the otologic surgeon upon exploration because of conductive hearing loss in patients with chronic otitis media. These nonotosclerotic noncongenital lesions take three pathologic forms: fibrous tissue fixation (chronic adhesive otitis media), hyalinization of collagen (tympanosclerosis), and new bone formation (fibro-osseous sclerosis). Fibrous tissue fixation appears on CT as nonbony, noncalcific soft-tissue debris encasing some or all of the ossicular chain. Tympanosclerosis appears as unifocal or multifocal punctate or weblike calcifications in the middle ear cavity or on the tympanic membrane. This debris may be in direct apposition to the ossicular chain or may replace the suspensory ligaments in symptomatic patients. New bone formation has been identified only in the attic and is the least common manifestation. Thick bony webs or generalized bony encasement may be present at CT. More than 300 patients with the clinical diagnosis of chronic otitis media have been examined. This study encompasses 23 proved cases. 相似文献
5.
Gallium-67 scintigraphy in multisystem malignant melanoma 总被引:1,自引:0,他引:1
6.
Carmona-Bayonas A; Soler IO; Gomez FI; Billalabeitia EG; Saura HP; Tafalla MSA; Diaz MP 《Annals of oncology》2007,18(7):1281
Mitotane is often considered the front-line hormonal therapyof adrenocortical carcinoma (ACC). An illustrative case concerningthis issue and the rationale to ponder other alternatives isreported. A 69 year-old woman, diagnosed with ACC was admittedwith hypertensive crisis, supraventricular tachycardia, congestiveheart-failure, diarrhoea and rabdomyolisis. Two years earlier,she had undergone 相似文献
7.
N. M. SOARES T. F. LEAL M. C. FIÚZA E. A. G. REIS M. A. L. SOUZA W. L. DOS‐SANTOS L. PONTES‐DE‐CARVALHO 《Parasite immunology》2010,32(4):259-266
This work aimed at investigating the lipid profile of zoonotic visceral leishmaniasis (VL) patients’ sera and the effect of lipoproteins on the in vitro production of tumour necrosis factor‐α (TNF‐α), interleukin (IL)‐6, IL‐10 and IL‐12 by Leishmania infantum‐infected and uninfected macrophages. Lipids were quantified in 26 VL patients’ sera and 26 healthy controls from a VL endemic area. The patients’ sera had higher triglyceride and very low density lipoprotein (VLDL) levels, and much lower apolipoprotein A1, total cholesterol, low density lipoprotein (LDL) and high density lipoprotein (HDL) levels than the control sera. Lipoprotein fractions were obtained by ultracentrifugation of sera. The addition of LDL and HDL to Leishmania‐infected and uninfected macrophages, in physiological concentrations, enhanced the production of IL‐6 and IL‐10, but not of IL‐12. LDL stimulated the production of TNF‐α only in infected macrophages, whereas HDL stimulated the production of lower amounts of TNF‐α in both infected and uninfected macrophages. VLDL stimulated only the production of IL‐10. It is proposed herein that LDL may influence the development of VL by promoting the production of TNF‐α by infected macrophages. A decrease in plasma LDL in some VL patients (to 20 mg/mL or less); however, would tend to reduce the production of TNF‐α and therefore to limit the development of immune‐mediated pathology, not withstanding the fact that it would perhaps increase the permissiveness of macrophages to Leishmania growth. 相似文献
8.
ObjectiveTo investigate the phytochemical screening and the effects of the aqueous extracts of the seeds of Irvingia gabonensis on the biochemical parameters of male guinea pigs.MethodsThe biochemical parameters were assayed using Randox Diagnostic kits, Phenolphthalein method and colorimetric method. The phytochemical screening was carried out using standard procedures.ResultsPhytochemical investigations revealed the presence of flavonoids, tannins, carbohydrate, alkaloids, terpenoids, steroids, volatile oils, saponins and cardiac glycosides. The aqueous extract of Irvingia gabonensis seeds (50–400 mg/kg) caused a statistically significant (P<0.05 ANOVA) decrease in the levels of total cholesterol, urea, uric acid, total protein, prostatic, alkaline, and acid phosphatases. The highest reduction effect was obtained with uric acid at 400 mg/kg of Irvingia gabonensis extract while the least effect was observed in total cholesterol. These effects were dose-and time-dependent.ConclusionsThis shows that the seeds of Irvingia gabonensis have hepatoprotective, nephroprotective and cardio protective properties. The study therefore, supports the claims on the use of the seeds of this plant by traditional medicine practitioners as a hepatoprotective and nephroprotective agent. Although further studies need to be done to isolate, identify and characterize the active principles in the seeds of this plant. 相似文献
9.
10.
Romero FI; Amengual O; Atsumi T; Khamashta MA; Tinahones FJ; Hughes GR 《Rheumatology (Oxford, England)》1998,37(8):883-888
The prevalence and clinical significance of antibodies against beta2-
glycoprotein I (anti-beta2GPI) and antibodies against oxidized low- density
lipoprotein (anti-ox-LDL) were evaluated as potential indicators of
arterial disease in patients with systemic lupus erythematosus (SLE) and
SLE with secondary antiphospholipid syndrome (APS). IgG anti-beta2GPI and
IgG anti-ox-LDL were measured by enzyme- linked immunosorbent assay (ELISA)
in serum samples from 118 patients with SLE, including 40 with secondary
APS. IgG anti-beta2GPI were positive in 17% (20/118) of SLE patients. The
presence and titres of IgG anti-beta2GPI were strongly associated with a
history of arterial thrombosis. Haemolytic anaemia was also significantly
associated with the presence of IgG anti-beta2GPI. The prevalence of IgG
anti-ox-LDL was 53% (63/118), but there was no association with arterial
thrombosis. No correlation between the values of anti-ox-LDL and those of
anti-beta2GPI was found. These results suggest that IgG anti- beta2GPI
could be a marker for arterial thrombosis in SLE patients, while IgG
anti-ox-LDL were not associated with arterial disease in this group of
lupus patients.
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