炎性介质在哮喘中的致炎机制与糖皮质激素的抗炎治疗

支气管哮喘是气道慢性炎症性疾病,炎性介质在哮喘的发病中,作用强大和广泛.糖皮质激素(GCS)尤吸入型GCS已被国内外哮喘研究专家确认为最有效的第一线抗炎药.下面通过哮喘发病炎症学说中的有关炎性介质,阐明GCS临床应用的理论依据.     

Effect of water restrictions on the physiological parameters,psychological behavior and brain c-Fos expression in rat

1 Introduction Exposure to hostile stressors causes a series of coor- dinated responses in the body, such as alterations of neu- roendocrine secretion, immune reaction and behavioral manifestation to maintain homeostasis stability and sur-vival of the organisms. Stressors are divided into two main categories: physical, or systemic, and psychological, or emotional / processive. Each stressor might activate a spe- cific central pathway to induce a special neuroendocrine response, even cause stre…     

脑肿瘤患者T-细胞亚群、β_2-微球蛋白的检测及其意义

承担细胞免疫功能的T-淋巴细胞是一个极为复杂的不均一的群体。依其个体发生的不同时期,可以划分为功能、特征不同的亚群。不同的亚群各有不同的具有特征性的分化抗原,各有不同的免疫功能。因此,检测T-细胞亚群以了解脑肿瘤患者的细胞免疫功能有一定意义。β_2微球蛋白(β_2-m)是一种小分子量蛋白,分子量为11,800。正     

Design and application research of nucleotide sequence analysis system software

INTRODUCTION　　From integrallevel and celllevel,the research of organism and diseasediagnosishave already entered molecular level.Molecular biology is the science to researchstructure and function of organism macromolecule.Based on differentgene code se-…     

尼莫地平对蛛网膜下腔出血预后影响的临床观察

<正> 蛛网膜下腔出血(SAH)最严重的并发症是脑血管痉挛(CVS),其发生率较高,是增加患者病死率和致残率的主要原因。CVS发病机理十分复杂,治疗方法多种多样,既往使用过地巴唑、异丙肾上腺紊、利多卡因等治疗,效果不理想。尼莫地平问世后,这种选择性作用于脑血管的钙离子拮抗剂在治疗CVS方面发挥了前所未有的作用。使SAH继发CVS所致的抽搐、颅压增高和病死率明显下降。