首页 | 本学科首页   官方微博 | 高级检索  
文章检索
  按 检索   检索词:      
出版年份:   被引次数:   他引次数: 提示:输入*表示无穷大
  收费全文   965篇
  免费   145篇
  国内免费   3篇
儿科学   14篇
妇产科学   5篇
基础医学   93篇
临床医学   100篇
内科学   119篇
皮肤病学   4篇
神经病学   2篇
特种医学   1篇
外科学   7篇
综合类   113篇
预防医学   630篇
眼科学   2篇
药学   22篇
肿瘤学   1篇
  2024年   1篇
  2023年   11篇
  2022年   38篇
  2021年   45篇
  2020年   66篇
  2019年   38篇
  2018年   39篇
  2017年   51篇
  2016年   32篇
  2015年   42篇
  2014年   86篇
  2013年   62篇
  2012年   64篇
  2011年   100篇
  2010年   85篇
  2009年   50篇
  2008年   57篇
  2007年   48篇
  2006年   41篇
  2005年   28篇
  2004年   19篇
  2003年   26篇
  2002年   13篇
  2001年   10篇
  2000年   5篇
  1999年   5篇
  1998年   5篇
  1997年   9篇
  1996年   5篇
  1995年   3篇
  1994年   3篇
  1993年   3篇
  1992年   3篇
  1991年   3篇
  1990年   4篇
  1989年   2篇
  1988年   7篇
  1987年   3篇
  1985年   1篇
排序方式: 共有1113条查询结果,搜索用时 78 毫秒
1.
2.
3.
4.
《Vaccine》2016,34(43):5175-5180
IntroductionThe continuous deployments of polio resources, infrastructures and systems for responding to other disease outbreaks in many African countries has led to a number of lessons considered as best practice that need to be documented for strengthening preparedness and response activities in future outbreaks.MethodsWe reviewed and documented the influence of polio best practices in outbreak preparedness and response in Angola, Nigeria and Ethiopia. Data from relevant programmes of the WHO African Region were also analyzed to demonstrate clearly the relative contributions of PEI resources and infrastructure to effective disease outbreak preparedness and response.ResultsPolio resources including, human, financial, and logistic, tool and strategies have tremendously contributed to responding to diseases outbreaks across the African region. In Angola, Nigeria and Ethiopia, many disease epidemics including Marburg Hemorrhagic fever, Dengue fever, Ebola Virus Diseases (EVD), Measles, Anthrax and Shigella have been controlled using existing polio Eradication Initiatives resources. Polio staffs are usually deployed in occasions to supports outbreak response activities (coordination, surveillance, contact tracing, case investigation, finance, data management, etc.). Polio logistics such vehicles, laboratories were also used in the response activities to other infectious diseases. Many polio tools including micro planning, dashboard, guidelines, SOPs on preparedness and response have also benefited to other epidemic-prone diseases. The Countries’ preparedness and response plan to WPV importation as well as the Polio Emergency Operation Center models were successfully used to develop, strengthen and respond to many other diseases outbreak with the implication of partners and the strong leadership and ownership of governments. This review has important implications for WHO/AFRO initiative to strengthening and improving disease outbreak preparedness and responses in the African Region in respect to the international health regulations core capacities.  相似文献   
5.
BackgroundGastroenteritis is one of the most common infectious diseases in the military populations and can diminish operational effectiveness and impede force readiness.ObjectivesThe present study investigates the cause and the source of an acute gastroenteritis outbreak that occurred during a military exercise of the Portuguese Army, in February 2013.Study DesignA retrospective investigation was performed and stool samples, food items and water were screened for common foodborne bacteria and viruses, namely Norovirus GI, Norovirus GII, Astrovirus, Rotavirus, Adenovirus and Sapovirus.ResultsFrom the total of 160 soldiers that participated in the military exercise 20 developed gastroenteritis (attack rate of 12.5%). Symptoms were predominantly vomiting (n = 17, 85%) and diarrhoea (n = 9, 45%). The first cases occurred 24–48 h after drinking water from the creek, the plausible origin of the outbreak. The epidemic peak was registered 2 days after and the last cases 6 days after, upon returning to base. No pathogenic bacteria were found in stools however virological analysis revealed the presence of multiple enteropathogenic viruses, namely Norovirus GI (GI.3), Norovirus GII (GII.4 New Orleans 2009), Astrovirus and Sapovirus, as single or co-infections. Food and water samples were not tested for the presence of viruses due to exhaustion of samples on bacteriological analysis.ConclusionsTo the best of our knowledge this is the first report of a viral gastroenteritis outbreak among military personnel in the Portuguese Army.  相似文献   
6.

Objectives

This study reported a hospital outbreak due to an extensively drug-resistant (XDR) OXA-72-producing strain of Acinetobacter baumannii (A. baumannii).

Methods and Results

The isolates were found to be genotypically indistinguishable by whole-genome multiple locus sequence typing, and to belong to the international clonal complex CC2. One of these isolates sequentially developed a high resistance to colistin and rifampicin under treatment, as a result of mutations in genes pmrB and rpoB, respectively. The blaOXA-72 gene was localised on a 10-kb transferable plasmid, named pAB-STR-1, whose sequence is nearly identical to that of another plasmid previously found in Lithuanian strains, pAB120.

Conclusion

This report highlighted the need to carefully monitor the emergence of colistin and rifampicin resistance in patients treated for infections with multidrug-resistant A. baumannii.  相似文献   
7.
8.
9.
《Vaccine》2018,36(31):4603-4609
Meningococcal disease is a serious public health threat given the seriousness of the illness, its disabling sequelae and its potential for epidemic spread. The disease is a concern during mass gatherings which provide conditions that facilitate transmission of infectious agents including Neisseria meningitidis. Implementation of appropriate meningococcal disease preventive measures during at-risk mass gatherings is crucial to prevent illness and outbreaks which may result in significant morbidity and mortality as well as local and international spread of the disease. These preventive measures should be informed by comprehensive risk assessments of the disease at those events and may include the use of vaccination, chemoprophylaxis and health awareness and educational campaigns, supported by efficient disease surveillance and response systems. The Hajj and Umrah religious mass gatherings in the Kingdom of Saudi Arabia are examples of how the implementation of such preventive measures was successful in reducing the incidence of meningococcal disease during these events as well as controlling and preventing outbreaks. Lessons learned from the Hajj and Umrah experience can inform meningococcal disease preventive strategies for other mass gatherings worldwide.  相似文献   
10.
汪慧  王大虎  陈纯  张周斌  李铁钢  王鸣 《疾病监测》2016,31(10):838-842
目的 了解广州市腹泻监测病例中诺如病毒分子流行病学特征。方法 2014-2015年选取广州市两家医院的门诊科室作为监测哨点,每间哨点医院每周采集5岁以下和5岁及以上腹泻病例粪便样本各3份,将采集的标本送至广州市疾病预防控制中心检测诺如病毒。阳性标本进行基因序列测定并进行同源性分析。通过中国传染病疫情和突发公共卫生事件网络直报系统收集2014-2015年广州市报告的诺如病毒感染引起的暴发疫情数据,开展流行病学分析。结果 共收集腹泻标本732份,诺如病毒阳性136份,阳性率为18.58%。各年龄组诺如病毒阳性率不同(2=20.39,P=0.001),其中5岁以下年龄组最高(24.21%)。基因分型结果显示GⅡ组133份(97.80%),GⅠ组3份(2.20%)。分别对2014年(4份)及2015年(5份)阳性标本进行测序,结果提示,2014年诺如病毒流行株以GⅡ.4 Sydney_2012变异株(75.00%)为主,2015年以GⅡ.17变异株(55.60%)为主。2014-2015年共报告诺如病毒感染性腹泻暴发疫情23起,其中14(60.80%)起由GⅡ组引起。结论 广州市诺如病毒感染性腹泻流行毒株仍以GⅡ组为主,其中2014年优势毒株为GⅡ.4 Sydney_2012变异株,2015优势毒株为GⅡ.17变异株。  相似文献   
设为首页 | 免责声明 | 关于勤云 | 加入收藏

Copyright©北京勤云科技发展有限公司  京ICP备09084417号