小儿肺炎支原体脑炎15例临床分析

肺炎支原体(MP)是小儿呼吸道感染的重要病原之一,有多种并发症,其中中枢神经系统损害是MP所致肺外疾患中最常见类型,于2003年1月2004年12月收治住院肺炎支原体感染患儿182例,其中并发脑炎者15例,占8.2%,现报道如下:     

DETECTION OF HIGH-PATHOGENICITY ISLAND-HARBORING ESCHERICHIA COLI ISOLATED FROM CHILDREN WITH DIARRHEA DISEASE IN CHINA

[Objective] To investigate the etiologicla status of etiologica status of high-pathogenicity island-harboring Escherichia coil(HPIEC) in dianhea disease among children. [Method] Diarrheagenic Esoherichia coli was isolated and identified from the stool specimens of 1032 children with dianhea diseases by culturing, serotyping, Polymerase chain reaction amplification (PCR), the High-pathogenicity island-harboring Esoherichia coli (HPIEC) was identified by PCR and in situ hybridization. [Results] A total of 652 strains of E.coli isolated from 1032 stool specimens and confirmed by serotyping, PCR and colony hybridization out of which 225 were identified as diarrheagenic E.coil,including 20 EPEC,81 ETEC, 47 SLTEC, 74 ESIEC, and 3 EIEC strains. 112(17.2%)irp2 virulent gene positive E.coli (HPIEC) were detected from the 652 strains, out of which 24 were from the 74 ESIEC strains and 17 from the 47 SLTEC strains. The typical clinical symptoms of children with diarrhea disease caused by HPI- harboring E.coli included anorexia(87.5%) ,abdominal pain(58.0%), diarrhea (75.9%,Over six episoders, mostly of mucous stool a day), and fever(50.9%). [Conclusion] High-pathogenicity island-harboring E.coli is one of the important pathogens of diarrhea diseases in children.     

大脑发育不全并发病毒性脑炎3例分析

<正> 近年来,病毒性脑炎的报道逐渐增多,但大脑发育不全并发病毒性脑炎的报道不多,现报道如下。1 临床资料 例1:男性,19岁,兰州籍。患者在淋雨后开始发热38℃左右,发病约1周后出现精神症状,患儿失眠,不回家睡觉,致使家人误认为离家出走而各处寻找。患儿因处于青春期,其母怀疑是否与异性有关,因患者与笔者为邻居,笔者建议家长带其到兰医二院就诊,当时医院考虑为“神经官能症”给予“巴氏合剂”等药物治疗,因效果不佳,患者兴奋躁闹,笔者     

儿童病毒性脑炎流行病学回顾性调查分析

目的回顾性总结我市儿童病毒性脑炎的流行病学特点，分析儿童病毒性脑膜炎的临床特点、病毒学特征、治疗及预后。方法对2005年3～7月在天水地区流行的儿童病毒性脑膜炎进行回顾性流行病学调查，检测小儿血清病毒特异性抗体。结果流行病学调查显示，人群分布主要为3～6岁儿童；时间分布从3月份开始，5～6月份达高峰；地区分布主要为城区；在送检的20例血清学标本中艾柯病毒和柯萨病毒IgM抗体阳性率分别为75％和50％；临床症状轻；预后良好。结论天水地区病毒性脑膜炎流行主要由肠道病毒引起，传播途径以消化道为主，临床特点较以前有不同之处，应引起临床医师重视。     

水痘并龟头炎1例报告

水痘是一种由病毒引起的急性传染病，较常见的并发症为皮肤和粘膜继发细菌感染，严重可引起脓毒血症，偶见脑膜脑炎、肺炎、脊髓炎等，并发龟头炎实数罕见。本人遇见1例，报道如下。     

FDA发布禁止含芦荟和珀希鼠李的OTC药物上市的最后法规

2002年5月9日,FDA发布了禁止含芦荟和珀希鼠李的缓泻OTC药物上市的最后法规,并于2002年11月5日生效。自生效之日起,所有含芦荟、芦荟提取物、芦荟花提取物,以及含珀希鼠李、casanthrol、珀希鼠李皮、珀希鼠李提取物、珀希鼠李流浸膏和珀希鼠李芳香流浸膏的用于缓泻的OTC药均被认为非“公认安全和有效”(GRASE),并被视作违反联邦法律的“新药”。