腹腔镜子宫切除术式的评价

1989年Reich施行首例腹腔镜辅助阴式子宫切除术（laparoscopic assisted vaginal hysterectomy，LAVH）。1991年Semm完成腹腔镜下筋膜内子宫切除术（classic intrafascial Semm hysterectomy，CISH）。经过10多年的发展，腹腔镜子宫切除已具有多种术式，技术趋于成熟，但选用何种术式更能达到预期效果有待进一步探讨，现就相关问题综述如下。     

Effect of water restrictions on the physiological parameters,psychological behavior and brain c-Fos expression in rat

1 Introduction Exposure to hostile stressors causes a series of coor- dinated responses in the body, such as alterations of neu- roendocrine secretion, immune reaction and behavioral manifestation to maintain homeostasis stability and sur-vival of the organisms. Stressors are divided into two main categories: physical, or systemic, and psychological, or emotional / processive. Each stressor might activate a spe- cific central pathway to induce a special neuroendocrine response, even cause stre…     

颌枕带牵引致双侧喉返神经完全麻痹1例

患者,女性,39岁。因患颈椎病按吕树森介绍的方法自行颌枕带牵引。即仰卧位,颈屈30°,牵引重量7.5kg(吕树森主编、外科学、人民卫生出版社,1985;478.)。2天后完全失语入院。体检:颈部僵直,活动受限。双眼视物模糊、流泪。双上肢肌力均减弱(3～4级),喉镜检查见双侧声带居旁正中位,声带不能闭合。X线片示颈椎生理曲度变直,椎体后缘骨质增生,椎间孔狭窄。诊断:1、双侧喉返神经麻痹;2、颈椎病。入院后用头颈胸石膏固定,并应用氟美松、维生素B_1、B_(12)等药物治疗,2天后语音恢复,3周后去除石膏出院。     

Design and application research of nucleotide sequence analysis system software

INTRODUCTION　　From integrallevel and celllevel,the research of organism and diseasediagnosishave already entered molecular level.Molecular biology is the science to researchstructure and function of organism macromolecule.Based on differentgene code se-…     

Puerarin blocks Na~+ current in rat ventricular myocytes

AIM: To study the effect of puerarin (Pue) on Na~+ channel in rat ventricular myocytes. METHODS: Whole-cell patch-clamp technique was applied on isolated cardiomyocytes from rats. RESULTS: Pue inhibited cardiac I_(Na) in a positive rate-dependent and dose-dependent manner, with an IC_(50) of 349 μmol/L. The kinetics of blockage of cardiac sodium channel by Pue resembled the ClassIa/Ic of antiarrhythmic agents. Pue 300 μmol/L did not alter the shape of the I-V curve of I_(Na), but markedly shifted the steady-state inactivation curve of I_(Na) towards more negative potential by 15.9 mV, and postponed the recovery of I_(Na) inactivation state from (21.9±1.6) ms to (54.4±3.4) ms (P<0.01 ). It demonstrated that the steady state of inactivation was affected by Pue significantly. CONCLUSION: Pue protected ventricular myocytes against cardiac damage and arrhythmias by inhibiting recovery from inactivation of cardiac Na~+ channels.