代文胶囊治疗高血压病的疗效观察

目的：观察代文胶囊治疗高血压病的临床疗效。方法：60例高血压病患者停用其它降压药1周服用代文胶囊80mg．qd晨服，服药1周后若舒张压仍／〉90mmHg者剂量改为160mg／d，治疗前及治疗后4周分别行动态血压监测，并观察该药的副作用，治疗前后肝肾功能及电解质变化。结果：38例服用80mg／d，22例服用160mg／d，显效33例（55％）有效21例（35％）无效10例（10％），总有效率90％，治疗前后无肝肾功能，血电解质变化。结论：代文胶囊疗效确切，降压作用平稳，能防止晨问血压升高，降低心血管事件发生，值得临床推广应用。     

32例腹部开放性损伤的救治体会

目的:探讨开放性腹部损伤的治疗方法。方法:回顾性分析1991年-1994年32例开放性腹部损伤患者的临床资料。结果:开腹探查26例,单纯缝合6例,阴性探查3例,二次手术2例,术后切口感染2例,感染性休克死亡1例,治愈31例,病死率为3.12%。结论:开放性腹部外伤,首先要根据临床表现及辅助检查判定内脏是否损伤,手术时机的掌握是治疗的关键。     

Pathological effects on mice by gambierol, possibly one of the ciguatera toxins

Gambierol was isolated from Gambierdiscus toxicus, which causes ciguatera fish poisoning. The acute toxicological effects induced in mice by synthesized gambierol were studied. The lethal doses were about 80 μg/kg by i.p. and i.v., and 150 μg/kg by p.o. The main injury by this toxin was observed in the lung, and secondary in the heart, resulting in systemic congestion. Another toxic effect was seen in the stomach, inducing hypersecretion and ulceration. With survival from the severe stage during the initial 3 h, recovery was favorable, especially after 4 days. Additional effects were not evident during 1-week post-administration observation.     

高原环境对部队适应人群内分泌系统的急性效应

本文对初入海拔5170米高原5日内未发生急性高山病的46名新战士进行了17项内分泌指标的检测,发现高原环境对适应人群内分泌系统的急性效应主要有:下丘脑一垂体应激反应增强;甲状腺功能增强;皮质醇分泌增多,醛固酮分泌减少,肾素活性降低,血管紧张素Ⅱ增多;性腺功能无明显变化。     

早期Alzheimer病患者语义记忆研究

目的：评估早期Alzheimer病患者语义记忆损害。方法：自编语义记忆测试工具，对22例Alzheimer病患者语义记忆损害评估作了纵向的研究．其中男10例，女12例。同时进行简明精神状况量表评定。结果：AD患者的2次MMSE评分明显差于正常对照组（P〈O．001）。在两个词的并列关系中，AD患者语义性启动操作起初并不同步。在并列条件测试中．先出现高启动效应．然后下降。在特征条件测试中，始终呈低启动效应。结论：AD病患者有着显著的动态语义记忆退化。     

神经导航在颅内肿瘤手术中的应用

目的探讨神经导航在神经外科显微手术中的应用。方法对101例颅内肿瘤患者均采用神经导航辅助的显微神经外科治疗。结果101例病变显微镜下全切89例(88．1%),次全切9例(8．9%),大部分切除3例(3．0%)；注册误差1．2～3．2mm,平均为(2．3±0．48)mm。术后症状改变或无变化92例(91．1%),9例(8．9%)出现不同程度的功能障碍,未出现术中及术后死亡。结论神经导航提供了实时、准确、可靠的定位,有助于提高手术疗效,降低术后神经功能损伤,缩短手术时间,使手术更微侵袭化。     

A simple model describes large individual differences in simultaneous colour contrast

We report experimental evidence for substantial individual differences in the susceptibility to simultaneous colour contrast. Interestingly, we found that not only the general amount of colour induction varies across observers, but also the general shape of the curves describing asymmetric matching data. A simple model based on von Kries adaptation and crispening describes the data rather well when we regard its free parameters as observer specific. We argue that the von Kries component reflects the action of a temporal adaptation mechanism, while the crispening component describes the action of the instantaneous, purely spatial mechanism most appropriately labeled simultaneous colour contrast. An interesting consequence of this view is that traditional ideas about the general characteristics of simultaneous contrast must be considered as misleading. According to Kirschmann’s 4th law, for instance, the simultaneous contrast effect should increase with increasing saturation of the surround, but crispening predicts the converse. Based on this reasoning, we offer a plausible explanation for the mixed evidence on the validity of Kirschmann’s 4th law. We also argue that simultaneous contrast, the crispening effect, Meyer’s effect and the gamut expansion effect are just different names for the same basic phenomenon.     

聚焦超声治疗慢性宫颈炎500例临床分析

目的 探讨聚焦超声治疗宫颈炎的临床疗效.方法 收治慢性宫颈炎700例,分为聚焦超声治疗组(超生治疗组)500例,微波治疗对照组200例.观察其临床症状、体征及疗效.结果 超声治疗组中、重度宫颈炎的疗效明显高于微波对照组,差异有显著意义(P＜0.05);两种方法治疗后,宫颈修复过程中阴道排液、出血等并发症的发生率,超声治疗组明显低于微波对照组,差异有显著意义(P＜0.05).结论 聚焦超声治疗宫颈炎疗效确切,副作用及并发症少,是目前治疗宫颈炎的一种有效方法.