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101.
Shunsuke Ohji Yosuke Kimura Yuhei Otobe Naohito Nishio Daisuke Ito Ryota Taguchi Hideyuki Ogawa Minoru Yamada 《The journal of spinal cord medicine》2021,44(2):262
Objective: Although the propulsion distance of a wheelchair is measured by some devices, measuring self-propulsion distance, excluding assistance propulsion distance by the caregiver, is difficult. This is a pilot study conducted to verify whether the propulsion distance of wheelchair users, excluding the assistance propulsion distance, can be measured using a cycle computer by attaching the touch switch.Methods: The wheelchair propulsion distance was measured using a cycle computer. We connected the touch switch and the cycle computer to the wheelchair to exclude assistance propulsion distance. We set the cycle computer to stop recording while the caregiver was touching the sensor. To confirm the propulsion distance using the cycle computer, the volunteer propelled the wheelchair on a rectangular facility with a total distance of 181 m, and the examiner confirmed the propulsion distance. The validation test to confirm the accuracy of the touch switch attached to the cycle computer was performed on a 50-m straight runway. The volunteer and caregiver propelled the wheelchair alternately by 10 m and continued until 50 m. The examiner confirmed the distance after 50-m propulsion.Results: In the 181-m rectangular facility, the propulsion distance that the volunteer propelled the wheelchair with the cycle computer was 180 m. In the 50-m straight runway, the propulsion distance was 30 m with caregiver assistance for 20 m.Conclusion: The present study showed that our modified device could measure the self-propulsion distance, excluding assistance propulsion distance in wheelchair users. 相似文献
102.
Jessica L. H. Phillips Mitchell K. Freedman Jeremy I. Simon Pedro K. Beredjiklian 《Hand (New York, N.Y.)》2021,16(2):164
Background: The Patient-Reported Outcomes Measurement Information System Upper Extremity (PROMIS UE) computer adaptive test was developed to improve precision and reduce question burden. We hypothesized that in patients with carpal tunnel syndrome (CTS): (1) PROMIS UE would correlate with established patient-reported outcome measures (PROs); (2) the time and number of questions required would be lower than current metrics; (3) there would be no floor or ceiling effects; and (4) PROMIS UE would not correlate with disease severity. Methods: Patients undergoing electrodiagnostic evaluation found to have a primary diagnosis of unilateral CTS prospectively completed PROMIS UE, Quick Disabilities of the Arm, Shoulder and Hand (qDASH), and Boston Carpal Tunnel Syndrome Questionnaire (BCTQ). Electrophysiologic and clinical severity was recorded. The relationships among PROs were described with Spearman coefficients. A floor or ceiling effect was confirmed if >15% of patients achieved the lowest or highest possible score, respectively. Results: Fifty-one patients (average, 53.9 years) were enrolled. An excellent correlation was identified between PROMIS UE and qDASH (R = −0.76, P < .001). There was a good correlation between PROMIS UE and BCTQ (R = −0.58, P < 0.001). The PROMIS UE required less time and fewer questions than qDASH and BCTQ (P = .02 and P < .001). There were no floor or ceiling effects. Neither neurophysiologic nor clinical severity correlated with PROMIS UE (R = 0.24, P > .05 and R = −0.18, P > .05). Conclusions: The PROMIS UE has an excellent correlation with qDASH and a good correlation with BCTQ in patients with CTS. Furthermore, PROMIS UE required less time and fewer questions than established PROs. Used as a single PRO, PROMIS UE represents a practical alternative to current metrics in patients with CTS. 相似文献
103.
Pooriput Waongenngarm Allard J van der Beek Nipaporn Akkarakittichoke Prawit Janwantanakul 《Scandinavian journal of work, environment & health》2021,47(4):306
Objective:This study evaluated the effects of the promotion of active breaks and postural shifts on new onset of neck and low-back pain during a 6-month follow-up among high-risk office workers.Methods:A 3-arm cluster-randomized controlled trial with 6-month follow-up was conducted among healthy but high-risk office workers. Participants were recruited from six organizations in Bangkok, Thailand (N=193) and randomly assigned at cluster level into active break intervention (N=47), postural shift intervention (N=46), and control (N=100) groups. Participants in the intervention groups received a custom-designed apparatus to facilitate designated active breaks and postural shifts during work. Participants in the control group received a placebo seat pad. The primary outcome measure was new onset of neck and low-back pain during 6-month follow-up. Analyses were performed using Cox proportional hazard models.Results:One-hundred and eighty-six (96%) predominantly female participants were successfully followed up over six months. New onset of neck pain during the 6-month follow-up occurred in 17%, 17%, and 44% of the participants in the active break, postural shift, and control groups, respectively. For new onset of low-back pain, these percentages were 9%, 7%, and 33%, respectively. Hazard rate (HR) ratios after adjusting for biopsychosocial factors indicated a protective effect of the active break and postural shift interventions for neck pain [HRadj 0.45, 95% confidence interval (CI) 0.20–0.98 for active break and HRadj 0.41, 95% CI 0.18–0.94 for postural shift] and low-back pain (HRadj 0.34, 95% CI 0.12–0.98 for active break and HRadj 0.19, 95% CI 0.06–0.66 for postural shift).Conclusion:Interventions to increase either active breaks or postural shifts reduced new onset of neck and low-back pain among high-risk office workers. 相似文献
104.
单片微机化微弱发光测量仪及其在肿瘤研究中的初步应用 总被引:2,自引:0,他引:2
单片微机化微弱发光测量仪由中科院生物物理所和北京科龙生物医学技术开发公司研制成功。该仪器适用于肿瘤研究中生物医学样品的微弱发光的测量。测量样品的重复性优于0.8%,稳定性优于0.5%,线性相关系数达0.9997,不仅可以进行样品的发光强度测量,还可以进行动力学曲线的测量以及样品发射光谱的测量。光谱在400nm-750nm范围内。测量方式可选择手动、半自动和自动计时三种。测量结果表明,荷瘤裸鼠血液微 相似文献
105.
106.
目的:观察青年和老年期大鼠下丘脑弓状核阿黑皮素原mRNA(POMC mRNA)的表达水平。方法应用原位杂交技术显示POMCmRNA和用计算机图像分析观察杂交信号的强弱及阳性细胞的面积,结果:与青年组相比,老年组下丘脑弓状核及其附近区域POMCmRNA阳性神经元的灰度下降,POMCmRNA阳性神经元的数目无明显变化,结论:老年期POMCmRNA阳性神经元相应的mRNA表达水平下降可能是下丘脑的POMC基因衍生肽表达水平下降的原因之一。 相似文献
107.
脊椎骨折的CT影像和MRI对照分析 总被引:2,自引:0,他引:2
目的:比较和评价CT扫描和MRI二种影像学方法在脊椎骨折诊断中的作用。方法:对35例CT扫描和同时作MRI的23例诊断为脊椎骨折的病例进行对照分析。结果:CT表现为椎体纵或横形骨折崩解,终板骨折移位并突入椎管,椎管狭窄,椎板,横突及棘突骨折;MRI同时还显示了脊髓受压信号异常及后纵韧带、棘间韧带、椎间盘的撕裂。结论:CT、MRI能对脊椎骨折明确诊断,MRI能清楚地显示脊髓损伤的各种病理改变。 相似文献
108.
109.
七氟醚注入法紧闭麻醉 总被引:3,自引:0,他引:3
目的 设计注入法七氟醚紧闭麻醉的投药方案。方法 选择 2 2ASAⅡ~Ⅲ级择期胸部及上腹部手术病人 ,芬太尼 1.5 μg·kg-1,异丙酚 2mg·kg-1静脉快速诱导行气管插管。氧气流量 0 18~ 0 31·min-1,微量注射泵将七氟醚注入麻醉环路吸气支 ,维持成人呼气末靶浓度为 2 %、儿童 2 2 %。依据麻醉药药代动力学模型模拟值外推的公式计算出各时段的七氟醚注入量。结果 实测成人靶浓度中位数为 1 9% ,第 10~ 90百分点为 1 7%~ 2 2 %。预测偏性中位数为 - 6 .2 8% ;第 10~ 90百分点为 - 2 0 %~ 5 %。实施误差中位数为 13 71% ,第 10~ 90百分点为 5 %~ 2 0 %。麻醉期间偏性平均值为 - 3.5 1% ,95 %可信限为 - 2 3.5 2 %~ 16 .49%。平均值与 0比较无统计学差异 (P >0 0 5 )。结论 药代动力学模型模拟值外推的公式计算出各时段的七氟醚注入量可迅速达到并维持较稳定的呼气末靶浓度。不需要复杂地计算和频繁更变注入速率 ,仅利用微量注射泵和通用的麻醉机即可获得满意的麻醉效果。 相似文献
110.
成年大鼠纹状体、边缘区和苍白球的计算机三维重建 总被引:3,自引:0,他引:3
目的 建立和了解成年大鼠纹状体、边缘区和苍白球在脑中的立体形态和相互关系 .方法 在大鼠脑的连续冠状切片 Nissl染色的基础上通过 Onyx2超级图形工作站应用计算机图形技术进行了三维重建 .结果 边缘区位于尾壳核和苍白球之间 ;尾壳核的立体形态呈近似的内凹半球形 ,从嘴侧到尾侧随着脑平面的增宽尾壳核逐渐向外侧 (即靠近外轮廓的方向 )移位 ,体积为 (37.77± 9) m m3,最大嘴尾径为 6 .2mm;最大背腹径为 4.9m m;最大内外径为 3.5 2 9mm.苍白球呈块形 ,位于尾壳核的内侧 ,除内侧外其他三个方向均被尾壳核包绕 ,体积为 (4.0 5± 0 .0 6 ) mm3,最大嘴尾径为 4.41mm,最大背腹径为 2 .6 45 mm ,最大内外径为 1.5 44 m m.边缘区呈现一个片状扇形结构 ,体积为 (0 .48± 0 .0 2 ) mm3,最大嘴尾径为 1.6 m m,最大背腹径为 2 .15 8m m,最大内外径为0 .17mm;同尾壳核和苍白球一样从嘴侧到尾侧随着脑平面的增宽边缘区亦逐渐向外侧 (即靠近外轮廓的方向 )移位 ,其移位的幅度亦明显大于脑平面增宽的幅度 ;整个边缘区从嘴侧到尾侧呈均匀变化 ,其片状逐渐变宽 ,长度 (背腹径 )逐渐变小 ,从而形成一个盘状结构 .结论 建立了大鼠脑纹状体、边缘区和苍白球的三维立体结构 相似文献