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21.
H. Iwata T. Otoshi N. Takada T. Murai S. Tamano T. Watanabe Y. Katsura S. Fukushima 《Urological research》1995,23(1):27-32
A series of 8 rat and 16 mouse invasive bladder carcinomas were investigated for the presence of silverstained nucleolar organizer regions (AgNORs) to clarify whether this parameter is applicable to the estimation of their invasive character. With regard to number of AgNORs per cell, neither rat nor mouse carcinomas showed any difference between invasive and noninvasive sites within the same tumor. However, the frequency of cancer cells bearing bizarre dots, irregular in size and shape, was significantly higher at sites of actual invasion. Quantitative data generated using an image analyzer revealed significantly lower values for NOR roundness and significantly larger NOR size in invasive sites than in noninvasive sites in all groups. Double staining for the proliferation marker proliferating cell nuclear antigen (PCNA) and AgNORs was performed on eight rat carcinomas and a close correlation between the two was confirmed. Thus the number of AgNORs in PCNA-positive cells was significantly greater than in PCNA-negative cells. Furthermore, a particularly strong correlation was observed for incidences of PCNA-positive cells and bizarre dots (P<0.01). The quantitative data also demonstrated significant differences in size and shape of dots. It is concluded that AgNORs have diagnostic value for the invasive character of bladder carcinomas. 相似文献
22.
Bertalanffy H. Kretzschmar H. Gilsbach J. M. Ott D. Mohadjer M. 《Acta neurochirurgica》1990,104(3-4):151-155
Summary This case report describes a patient presenting with symptoms of increased intracranial pressure, whose computerized tomographic (CT) scan was highly suggestive of a large low-grade glioma invading the basal ganglia. Magnetic resonance imaging (MRI) revealed a well-demarcated space-occupying mass of increased intensity in the left lateral ventricle and adjacent white matter. Following stereotactic biopsy, which yielded a homogeneous jelly-like material, the mass was removed microsurgically and was found to be most like a colloid cyst on histological examination. Discussion focusses on the clinical and differential diagnostic implications of this very unusual combination of findings. 相似文献
23.
腹腔镜卵巢穿刺内凝治疗多囊卵巢不孕症的临床研究 总被引:2,自引:0,他引:2
目的探讨腹腔镜卵巢穿刺内凝对多囊卵巢不孕症的治疗价值。方法151例腹腔镜卵巢穿刺内凝术(实验组)和151例开腹卵巢楔切术(对照组)治疗多囊卵巢不孕症配对对比研究。结果实验组的手术时间33.1±7.2min,术中失血15.6±4.7ml,总排卵率92.05%,总妊娠率49.67%,均优于对照组(P<0.01);术后雄激素、LH/FSH下降幅度小于对照组(P<0.01)。随时间推移,两组术后排卵巢、妊娠率均有下降倾向,而术后雄激素、LH/FSH则有逐渐回升的倾向。结论腹腔镜卵巢穿刺内凝术对多囊卵巢不孕症有较好的治疗效果 相似文献
24.
经逆转录病毒载体将人GM-CSF基因导入人膀胱癌细胞株BIU-87细胞中,建立了转基因细胞株BIU/GM。经流式细胞仪行细胞DNA周期分析表明GM-CSF基因的导人及表达对BIU-87细胞的增长无影响。免疫荧光测定发现转GM-CSF基因及表达不能促进BIU-87细胞表面HLA-ABC、DR、DQ抗原的表达。转基因瘤细胞株经6000rad X射线照射灭活后,丧失增殖能力,逐步死亡,但能维持一定水平的GM-CSF分泌活性达两周以上。从而为制备灭活的转基因瘤苗提供了初步经验。 相似文献
25.
Incidence of post-lumbar puncture syndrome reduced by reinserting the stylet: a randomized prospective study of 600 patients 总被引:1,自引:0,他引:1
The post-lumbar puncture syndrome (PLPS) can best be explained by prolonged spinal fluid leakage owing to delayed closure
of a dural defect. Its incidence after spinal anaesthesia is much lower than after diagnostic lumbar puncture (LP). This difference
could be caused by a strand of arachnoid, which might enter the needle with the outflowing cerebrospinal fluid (CSF) during
diagnostic LP and upon removal of the needle be threaded back through the dura to produce prolonged CSF leakage. To find a
technique that further reduces the incidence of PLPS, this hypothesis was tested by evaluating the effect that reinserting
the stylet before removing the needle had on the incidence of PLPS. By reinserting the stylet to the tip of the needle, the
hypothesized strand would be pushed out, thereby reducing the frequency of PLPS. Sprotte’s “atraumatic needle” (21 gauge)
was used for LP. A total of 600 patients participated in the prospective study. They were randomized into two groups and questioned
about their complaints every day for up to 7 days after the LP. All LPs were performed by two experienced neurologists (T.B.,
M.S.). In 300 patients, the stylet was reinserted to the tip of the needle; in the other 300 it was not reinserted. Whereas
49 of the 300 patients without reinsertion developed PLPS, only 15 of the 300 patients with reinsertion did. This significant
difference (16.3 vs 5.0%, P < 0.005, chi square test) supports our hypothesis. On the basis of our results, we recommend reinserting the stylet before
removing the needle in order to reduce the incidence of PLPS.
Received: 30 September 1997 Received in revised form: 9 March 1998 Accepted: 20 March 1998 相似文献
26.
RAMASWAMY MANIKANDAN YVONNE BURKE SHALOM JOSEPH SRIRANGAM GERALD NICHOLAS COLLINS 《International journal of urology》2003,10(12):667-668
Involvement of the urinary bladder in an inguinal hernia is common, but massive bladder hernia is rare. Most urinary bladder herniations are discovered and repaired during surgery. We report a case of large incarcerated inguino-scrotal hernia, which was reduced only to present as a scrotal abscess and vesicocutaneous fistula; an unusual complication. The patient was managed conservatively due to underlying comorbidities. 相似文献
27.
28.
29.
目的 介绍阴道B超介导下后穹窿穿刺治疗盆腔囊肿的方法和疗效。方法 38例盆腔囊肿病人在阴道B超介导下行后穹窿穿刺术 ,并与 2 8例住院行经腹囊肿切除术病人进行对比。结果 阴道B超介导下后穹窿穿刺术治愈率 10 0 % ,复发率 2 6 %。与经腹囊肿切除术相比 ,手术时间短 ,术中出血少 ,病人可接受程度高 ,花费少 ,差异显著 (P <0 0 1)。结论 阴道B超介导下后穹窿穿刺治疗盆腔囊肿 ,方法简便、安全高效、创伤小、价廉 ,是一项理想的保守疗法 ,值得推广应用。 相似文献
30.
腺性膀胱炎三种治疗方法治疗效果的随访观察 总被引:2,自引:0,他引:2
目的 比较腺性膀胱炎三种治疗方法的效果。方法 86例腺性膀胱炎患者分别行膀胱药物灌注、经尿道电切、经尿道电切加膀胱药物灌注治疗。随访观察症状缓解程度和膀胱镜病检结果 1年。结果 73例完成了随访调查 ,占 84.9%。三种方法治疗后症状缓解程度 ,差异无显著性意义 (P >0 .0 5 ) ;膀胱镜病检复查 ,灌注治疗效果好于电切治疗效果 ,综合治疗效果好于电切治疗效果 ,差异具有显著性意义 ;比较灌注治疗后膀胱镜病检阴性例数 ( 2 2 /2 8)与综合治疗后膀胱镜病检阴性例数 ( 3 0 /3 4) ,差异无显著性意义 ( χ2 =1.0 60 ,P =0 .3 0 3 )。结论 膀胱药物灌注和经尿道电切加膀胱药物灌注的膀胱镜病检复查 ,效果好于电切治疗的效果。 相似文献