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31.
目的探讨不同性别SD大鼠血清生化值的差异。方法采用全自动生化分析仪对禁食条件下,不同性别SPF级SD大鼠血液中的丙氨酸氨基转移酶(ALT)、天门冬氨酸氨基转移酶(AST)、总蛋白(TP)、白蛋白(ALB)、总胆红素(TBiL)、碱性磷酸酶(ALP)、尿素(Urea)、肌酐(Cre)、葡萄糖(Glu)、总胆固醇(TC)、甘油三酯(TG)、肌酸激酶(CK)等生化指标进行测定。结果雄性SD大鼠的ALT、AST、ALP和K要显著高于雌性SD大鼠,而TP、ALB、TBiL和CR要显著低于雌性SD大鼠。结论在长期毒性试验中,要考虑性别因素对血液生化指标的影响,建议各组别雌、雄SD大鼠的数量合理设置,并根据性别分开统计血液生化值。 相似文献
32.
目的探讨代谢综合征患病率随性别和年龄的变化趋势。方法对2006年1~12月和2009年1~12月笔者医院的健康体检人群进行回顾性调查。男性:2006年1619例,2009年2202例;女性:2006年418例,2009年636例。MS诊断标准采用NCEP-ATPⅢ的中国人修订标准。结果男性2009年的MS患病率(41.2%vs 36.6%,P=0.003)较2006年显著增加了4.6%;女性2009年MS患病率(33.2%vs 36.1%,P>0.05)较2006年降低了2.9%。年龄分层显示,男性在44岁以下MS患病率有下降趋势,45岁后各年龄组皆呈增加趋势,特别是45~64岁年龄段MS患病率显著增加(P<0.05);女性年龄小于64岁MS患病率呈降低趋势,65岁后呈增加趋势。2006~2009年MS各危险因子变化率比较显示,2009年男性WC、HDL-C、FPG阳性例数明显增加(P<0.05);女性TG阳性例数明显减少(P<0.05)。结论 2006~2009年北京某公司MS患病率变化趋势呈现明显的性别和年龄差异。男性45~64岁和女性65岁后人群是MS患病的重点防治人群。 相似文献
33.
Gender differences in sexual and injection risk behavior among active young injection drug users in San Francisco (the UFO study) 总被引:5,自引:0,他引:5
Jennifer L. Evans Judith A. Hahn Kimberly Page-Shafer Paula J. Lum Ellen S. Stein Peter J. Davidson Andrew R. Moss 《Journal of urban health》2003,80(1):137-146
Female injection drug users (IDUs) represent a large proportion of persons infected with HIV in the United States, and women
who inject drugs have a high incidence of hepatitis B virus (HBV) and hepatitis C virus (HCV) injection. Therefore, it is
important to understand the role of gender in injection risk behavior and the transmission of blood-borne virus. In 2000–2002,
844 young (<30 years old) IDUs were surveyed in San Francisco. We compared self-reported risk behavior between 584 males and
260 female participants from cross-sectional baseline data. We used logistic regression to determine whether demographic,
structural, and relationship variables explained increased needle borrowing, drug preparation equipment sharing, and being
injected by another IDU among females compared to males. Females were significantly younger than males and were more likely
to engage in needle borrowing, ancillary equipment sharing, and being injected by someone else. Females were more likely than
males to report recent sexual intercourse and to have IDU sex partners. Females and males were not different with respect
to education, race/ethnicity, or housing status. In logistic regression models for borrowing a used needle and sharing drug
preparation equipment, increased risk in females was explained by having an injection partner who was also a sexual partner.
Injecting risk was greater in the young female compared to male IDUs despite equivalent frequency of injecting. Overlapping
sexual and injection partnerships were a key factor in explaining increased injection risk in females. Females were more likely
to be injected by another IDU even after adjusting for years injecting, being in a relationship with another IDU, and other
potential confounders. Interventions to reduce sexual and injection practices that put women at risk of contracting hepatitis
and HIV are needed. 相似文献
34.
Bobak M 《European journal of epidemiology》2003,18(1):15-18
This paper examined whether international variations in absolute and relative gender differences in mortality are related to the overall mortality rates, and whether the international variation in gender gap in mortality can in part be explained by smoking. I used data on mortality from all causes in 32 European countries published by the World Health Organisation, and indirect estimates of mortality attributable to smoking in the age band 35–69 years by Peto et al. The main analyses were restricted to the age band 35–69 years but results for mortality at all ages were virtually identical. The overall mortality rates (both sexes combined) were strongly related to absolute gender differences (r = 0.91) but only weakly to relative differences (r = 0.35). The gender gap was larger in eastern than in western Europe for rate differences (1005 vs. 530 per 100,000, respectively), but it was similar for rate ratios (2.3 vs. 2.1, respectively). Both absolute and relative gender differences in mortality were strongly related to the difference between men and women in the proportion of all deaths attributed to tobacco (partial correlations, after controlling for the overall death rates, were 0.59 and 0.66, respectively). Excluding tobacco-related deaths attenuated the associations between the overall mortality rates with absolute differences (r = 0.70) and reduced the difference in the absolute gender gap between eastern and western Europe. More importantly, excluding tobacco-related deaths eliminated entirely the association with relative differences (r = –0.15) as well as any suggestion that the relative gender gap is larger in eastern than in western Europe. These results show that tobacco plays an important role in generating international differences in the size of gender gap in mortality. The much discussed association between the overall life expectancy and the gender gap in life expectancy is a numerical product of absolute death rates (differences in life expectancy are driven by differences in rates). The association of overall mortality with male/female mortality ratios is much weaker. 相似文献
35.
Halileh S Abu-Rmeileh N Watt G Spencer N Gordon N 《Maternal and child health journal》2008,12(5):606-612
The objective of this cross sectional study is to look at determinants of birth weight and their association with the gender
of the baby in 2,795 full term children living in the occupied Palestinian territory, derived from a stratified random sample
of 2,994 households in the West Bank and 2,234 households in the Gaza Strip. The response rate was 85%. Multivariable analysis
using analysis of variance for mixed models showed that sex and birth order, maternal age and education and to a lesser extent
region were determinants of birth weight for all children. The effect of maternal education on birth weight differed for female
and male infants, tending to be relatively unchanged for male infants and with mean birth weights increasing with maternal
education in female infants. The effect of birth order differed by maternal age, with mean birth weight increasing with maternal
age for first and second births; but being unaffected by maternal age for infants of birth order greater than two. We conclude
that birth weight is influenced by common biological determinants across cultures, but is also influenced by social, ethnic,
and environmental factors that are culture specific, of which some might be gender related.
相似文献
Samia HalilehEmail: |
36.
Tessa Brik Lieke J.J.J. Vrouenraets Sebastian E.E. Schagen Andreas Meissner Martine C. de Vries Sabine E. Hannema 《The Journal of adolescent health》2019,64(5):589-593
Purpose
The primary aims of the study are to examine the rate of attempted fertility preservation (FP) among a Dutch cohort of transgirls who started gonadotropin-releasing hormone analog treatment and the reasons why adolescents did or did not choose to attempt FP.Methods
The study was a single-center retrospective review of medical records of 35 transgirls who started gonadotropin-releasing hormone analog treatment between 2011 and 2017.Results
Ninety-one percent of adolescents were counseled on the option of FP. Thirty-eight percent of counseled adolescents attempted FP, and 75% of them were able to cryopreserve sperm suitable for intrauterine insemination or intracytoplasmic sperm injection. Younger and Caucasian transgirls were less likely to attempt FP. No specific reason for declining FP was known in 33% adolescents, 32% of adolescents were not able to produce a semen sample because of early puberty, 17% felt uncomfortable with masturbation, 17% did not want to have children, and 13% wanted to adopt.Conclusions
One third of adolescents attempted FP, which is much more than the percentage reported in previous studies from the United States. One third of the transgirls could not make use of FP because they were unable to produce a semen sample because of early pubertal stage. For these adolescents, alternatives need to be explored. 相似文献37.
This study investigates the relation between early life conditions and adult obesity in France, using a rich data set collected through the 2003 nationally representative Life History Survey. No salient factor emerged in men, while in women, after controlling for current socio-demographic characteristics, a relation was found between obesity and the following factors: father's occupation (OR = 3.2 for women whose father was a clerical worker, versus those whose father was in a higher-level occupation); experience of economic hardship in childhood (OR = 2.0), and; high parity (OR = 2.1 for parities of more than 3 versus parity of 1). Neither early family history nor mother's working status surfaced as significant factors. Those findings highlight a definite gender pattern, with a strong association between early disadvantage and obesity in women, but not in men. Potential mechanisms are discussed, particularly the “habitus”, the “thrifty phenotype” and the “feast–famine” hypotheses, and possible interactions with childbearing and motherhood. An integration of social and biological perspectives is needed to reach a better understanding of the processes involved, and to achieve progress in primary and secondary prevention. 相似文献
38.
目的 探讨西南地区不同性别铁路职业人群高尿酸血症(HUA)患病情况及影响因素。方法 以2020年在中国铁路成都局集团公司联合成都大学附属医院开展的健康列车上体检的23 265名在职职工为研究对象,收集人口学特征和体检指标,采用单因素分析和logistic回归分析,不同性别分层分析。结果 HUA检出率为37.4%,其中男性(39.3%)明显高于女性(13.4%)(P<0.001)。在男性中饮酒、当前吸烟、体质指数(BMI)超标、高甘油三酯(TG)、高低密度脂蛋白胆固醇(LDL-C)、低高密度脂蛋白胆固醇(HDL-C)、慢性肾病(CKD)的检出率分别为71.8%、61.6%、55.6%、46.1%、38.5%、18.5%、2.3%,均高于女性(22.0%、7.3%、29.4%、18.3%、18.6%、5.4%、0.6%,P<0.001)。性别分层logistic回归分析显示:超重/肥胖、高TG、CKD是男性和女性HUA共同的危险因素(OR>1,P<0.05),已婚是共同的保护因素(OR<1,P<0.05)。另外,在男性,行车关键岗位(OR=1.07,95... 相似文献
39.
40.
Luis A. Kluth Malte Rieken Evanguelos Xylinas Matthew Kent Michael Rink Morgan Rouprêt Nasim Sharifi Asha Jamzadeh Wassim Kassouf Dharam Kaushik Stephen A. Boorjian Florian Roghmann Joachim Noldus Alexandra Masson-Lecomte Dimitri Vordos Masaomi Ikeda Kazumasa Matsumoto Masayuki Hagiwara Eiji Kikuchi Yves Fradet Jonathan Izawa Ricardo Rendon Adrian Fairey Yair Lotan Alexander Bachmann Marc Zerbib Margit Fisch Douglas S. Scherr Andrew Vickers Shahrokh F. Shariat 《European urology》2014