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Charcot neuropathic osteoarthropathy (CN) is a progressive disease affecting the bones, joints and soft tissue of the foot and ankle, most commonly associated with diabetic neuropathy. Patients with diabetes complicated by CN have especially high morbidity, frequency of hospitalisation, and therefore, significant utilisation of expensive medical resources. The diagnosis of early CN can be challenging and is based on clinical presentation supported by various imaging modalities. Imaging is important for the detection of early CN and is useful in monitoring progression and complications of the disease. The later stages of CN are potentially devastating for individuals and present an increasing socioeconomic challenge for health systems. The astute radiologist, particularly in the context of a multidisciplinary team, plays a critical role in diagnosis of the primary disease and its complications. This review article aims to outline the key features of CN, emphasising current clinical and radiologic concepts as an aid for the practising radiologist. 相似文献
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A 40-year-old woman was hospitalized for investigation of dry cough, dyspnoea, and pain and swelling in the large joints of the arms and legs. Chest CT revealed a left hilar mass with partial atelectasis in the apical segment of the left lower lobe. X-ray of the wrists, elbows, ankles and knee joints showed a periosteal reaction, associated with hypertrophic pulmonary osteoarthropathy. Endobronchial biopsy suggested a pulmonary epithelioid haemangioendothelioma. Whole left lung resection was performed and the patient died of respiratory failure 1 month postoperatively. 相似文献
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KAZUYA MAKIYAMA KAZUO ISHIDA WALTER ZEA-IRIARTE MINORU ITSUNO MASAKI YAMAKAWA NORIHIKO MORI 《Journal of gastroenterology and hepatology》1996,11(7):692-695
A case of Hippocratic digital associated with secondary hypertrophic osteoarthropathy complicating Crohn's disease in a 29 year old Japanese male is reported. Hippocratic digital, or finger clubbing, complicating inflammatory bowel disease has been frequently reported in the Western hemisphere. However, its association with secondary hypertrophic osteoarthropathy has been very rarely found in that disease. In Japan, Hippocratic digital has not been described previously. With regard to the pathogenesis of Hippocratic digital and secondary hypertrophic osteoarthropathy, the theory that both entities belong to the same pathological spectrum and that megakaryocytes or platelet clumps may play the most important role, is discussed. 相似文献
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针灸治疗膝关节骨性关节炎60例疗效观察 总被引:5,自引:1,他引:4
目的 :观察针刺与药物治疗膝关节骨性关节炎的疗效差异。方法 :针灸治疗组 6 0例取内、外膝眼、阳陵泉、足三里、委中、承山、三阴交治疗 ,药物对照组 5 0例口服布洛芬加骨刺片治疗并进行比较。结果 :治疗组总有效率为 10 0 % ,对照组总有效率 92 % ,两者之间疗效相比 ,经统计学处理 ,差异有显著性意义 (P <0 .0 5 )。治疗组无一例出现副作用。结论 :针灸治疗本病疗效优于对照组。 相似文献
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