全文获取类型
收费全文 | 9039篇 |
免费 | 712篇 |
国内免费 | 150篇 |
专业分类
耳鼻咽喉 | 207篇 |
儿科学 | 95篇 |
妇产科学 | 27篇 |
基础医学 | 470篇 |
口腔科学 | 44篇 |
临床医学 | 693篇 |
内科学 | 1447篇 |
皮肤病学 | 30篇 |
神经病学 | 3044篇 |
特种医学 | 97篇 |
外科学 | 476篇 |
综合类 | 857篇 |
预防医学 | 202篇 |
眼科学 | 865篇 |
药学 | 558篇 |
3篇 | |
中国医学 | 599篇 |
肿瘤学 | 187篇 |
出版年
2024年 | 42篇 |
2023年 | 130篇 |
2022年 | 234篇 |
2021年 | 372篇 |
2020年 | 327篇 |
2019年 | 292篇 |
2018年 | 331篇 |
2017年 | 363篇 |
2016年 | 338篇 |
2015年 | 317篇 |
2014年 | 544篇 |
2013年 | 753篇 |
2012年 | 487篇 |
2011年 | 528篇 |
2010年 | 364篇 |
2009年 | 389篇 |
2008年 | 360篇 |
2007年 | 349篇 |
2006年 | 344篇 |
2005年 | 266篇 |
2004年 | 247篇 |
2003年 | 209篇 |
2002年 | 197篇 |
2001年 | 186篇 |
2000年 | 121篇 |
1999年 | 122篇 |
1998年 | 137篇 |
1997年 | 154篇 |
1996年 | 152篇 |
1995年 | 117篇 |
1994年 | 115篇 |
1993年 | 127篇 |
1992年 | 128篇 |
1991年 | 83篇 |
1990年 | 74篇 |
1989年 | 74篇 |
1988年 | 53篇 |
1987年 | 50篇 |
1986年 | 70篇 |
1985年 | 71篇 |
1984年 | 62篇 |
1983年 | 23篇 |
1982年 | 48篇 |
1981年 | 38篇 |
1980年 | 30篇 |
1979年 | 26篇 |
1978年 | 16篇 |
1977年 | 13篇 |
1976年 | 11篇 |
1969年 | 4篇 |
排序方式: 共有9901条查询结果,搜索用时 15 毫秒
51.
J. F. Bergmann O. Chassany P. J. Guillausseau M. Bayle S. Chagnon C. Caulin J. R. Sallenave 《European journal of clinical pharmacology》1992,43(2):121-124
Summary The aim of the study was to use a novel combination of two methods for the simultaneous evaluation of two effects of oral cisapride in 10 diabetic patients with autonomic neuropathy; gastric emptying time was measured by following radio-opaque markers and orocaecal transit time by the sulphasalazine-sulphapridine method. The study was of double-blind, randomized, placebo-controlled, cross-over design.It was possible to evaluate the effect of a prokinetic drug on gastric emptying and orocaecal transit times using these two noninvasive techniques at the same time. Cisapride significantly reduced both the gastric emptying (1.2 h versus 2.1 h) and orocaecal tansit (5.9 h versus 7.7 h) times. 相似文献
52.
53.
听神经病的纯音听阈检查结果分析 总被引:1,自引:1,他引:0
目的 探讨听神经病纯音听阈(PTT)检查的特征。方法 对48例听神经病患者的PTT检查结果进行分析,并与耳蜗性聋进行对照比较。结果 听神经病的PTT图有上升型、峰型、匙型、W型、倒S型、水平型和缓降型。双耳对称的PTT图有38例,不对称的有10例。听神经病的听阈升高程度呈轻、中度。左右耳听阈升高程度基本一致。低频听阈升高或以低频听阈升高为主的PTT图型占93.75%(90/96耳)。结论 双耳对称或基本对称的低频听阈升高或以低频听阈升高为主是听神经病的重要特征。 相似文献
54.
55.
目的:探讨糖尿病周围神经病(DPN)患者的临床特征与神经电生理变化。方法:分析97例DPN患者的临床特征,比较DPN组和对照组的神经传导速度(NCV)、远端潜伏期、远端波幅3个参数。结果:①临床特征以肢体麻木(59%)最多见、其次为疼痛(42%)。②患者组NCV、远端波幅值低于对照组,远端潜伏期比对照组延长;两组3个参数比较,除腓总神经远端波幅、尺神经感觉传导速度和正中、尺、腓肠神经远端潜伏期外,差异均有统计学意义(P<0.05)。结论:①DPN患者临床特征以肢体麻木和疼痛最多见;②检测NCV、远端潜伏期、远端波幅,能较早发现临床患者。 相似文献
56.
S. Matà S. Corzani R. Biagiotti S. Piacentini G. Siracusa M. G. Giudizi M. D. Mastio W. Borsini R. Taiuti A. Vultaggio S. Sorbi E. Maggi 《European journal of neurology》2007,14(10):1147-1153
Autoimmune mechanisms are postulated to play a role in the development and progression of dysimmune neuropathies (DN). We investigated the relation between lymphocyte number and marker expression, and disease activity in 20 patients with DN under intravenous immunoglobulins (IVIg) treatment. B- and T-lymphocyte markers were studied by flow cytometry of the expression of CD5, CD25, CD23 and CD38 markers on B cells and of CD3, CD4 and CD8 markers, respectively. These parameters were compared with those obtained from matched healthy volunteers. The proportions of CD38+ B cells were higher in patients compared with those of controls. Proportions of activated CD4+ and CD8+ T cells were comparable in peripheral blood mononuclear cells of patients and controls, but a significant reduction of the absolute numbers of CD3+, CD4+ and CD8+ cells were observed in DN patients. The percentages of CD25+ memory T cells were instead significantly increased in DN patients. Lastly, T-cell reduction and the CD19/CD38 ratio over total B (CD19+) cells directly correlated with a poor response to IVIg therapy. In DN, whereas T-cell number is reduced, activated T and B cells are increased, thus suggesting an intrinsic defect of the immune response. 相似文献
57.
Abstract. This study examined the ability of nitrova-sodilator treatment with isosorbide dinitrate to prevent the development of reduced nerve conduction velocity and nutritive blood flow in streptozotocin-induced diabetes mellitus in rats. Two month untreated diabetes caused approximately 23% and 13% reductions in sciatic motor and saphenous nerve sensory conduction velocity ( P < 0.001). Isosorbide dinitrate treatment provided 64.6 and 67.6% protection for motor and sensory nerves, respectively ( P < 0.01). Sciatic endoneurial nutritive blood flow was measured by microelectrode polarography and a hydrogen clearance technique. After 1 month untreated diabetes, flow was reduced by 41.9% ( P < 0.001). Isosorbide dinitrate treatment for 1 month in non-diabetic and diabetic rats significantly increased blood flow ( P < 0.01). When between-group variations in blood pressure were taken into account, vascular conductance increased by 29% and 31% in non-diabetic and diabetic rats, respectively ( P < 0.01). Thus, nitrovasodilator treatment improves nerve perfusion and function in experimental diabetes, probably by compensating for reduced endothelium-derived nitric oxide release or action. 相似文献
58.
Richard J. Lederman 《Muscle & nerve》1994,17(6):569-577
Over the past 10–15 years, there has been increasing interest in the health problems of performing artists. In this review, I will discuss the major playing-related disorders seen in instrumental musicians. Among the 672 instrumentalists evaluated, the major diagnoses identified included musculoskeletal disorders in 64%, peripheral nerve problems in 22.5%. and focal dystonia in 7%. Sixty percent of instrumentalists were female although males predominate in the group with focal dystonia. The average age of those evaluated was 32 years. Among musculoskeletal disorders overuse syndrome is the most common. Frequent peripheral nerve disorders include thoracic outlet syndrome, carpal tunnel syndrome, and ulnar neuropathy. A characteristic distribution of symptoms and signs is identified for each instrument group. Electrodiagnostic studies are an important part of the evaluation of these disorders. With carefully designed treatment, the majority of instrumental musicians can be returned to full and pain-free playing activities. The success rate is highest in some entrapment neuropathies but remains low in focal dystonia. © 1994 John Wiley & Sons, Inc. 相似文献
59.
Giuseppe Giuffre’ Vincenzo Schifano Maria Vadala’ 《Documenta ophthalmologica. Advances in ophthalmology》1995,91(3):255-263
We report on a case of idiopathic uveal effusion syndrome complicated by AION. To our knowledge such an association hasn't been previously described. We suggest that scleral thickening caused obstruction of vortex veins followed by uveal effusion and compression of posterior ciliary arteries within their intrascleral tract, leading to AION. Nevertheless it can't be excluded that AION was the result of mechanical compression on ciliary vessels of optic disc by choroidal detachment. 相似文献
60.