全文获取类型
收费全文 | 82961篇 |
免费 | 6661篇 |
国内免费 | 2491篇 |
专业分类
耳鼻咽喉 | 403篇 |
儿科学 | 2055篇 |
妇产科学 | 798篇 |
基础医学 | 6522篇 |
口腔科学 | 1133篇 |
临床医学 | 7779篇 |
内科学 | 9543篇 |
皮肤病学 | 657篇 |
神经病学 | 3303篇 |
特种医学 | 1919篇 |
外国民族医学 | 7篇 |
外科学 | 17009篇 |
综合类 | 14572篇 |
现状与发展 | 3篇 |
一般理论 | 5篇 |
预防医学 | 5993篇 |
眼科学 | 956篇 |
药学 | 6938篇 |
126篇 | |
中国医学 | 10213篇 |
肿瘤学 | 2179篇 |
出版年
2024年 | 281篇 |
2023年 | 1672篇 |
2022年 | 2710篇 |
2021年 | 4313篇 |
2020年 | 3539篇 |
2019年 | 3755篇 |
2018年 | 3330篇 |
2017年 | 3151篇 |
2016年 | 3023篇 |
2015年 | 2828篇 |
2014年 | 5595篇 |
2013年 | 5288篇 |
2012年 | 4549篇 |
2011年 | 5498篇 |
2010年 | 4906篇 |
2009年 | 3831篇 |
2008年 | 3640篇 |
2007年 | 3737篇 |
2006年 | 3453篇 |
2005年 | 2885篇 |
2004年 | 2381篇 |
2003年 | 2150篇 |
2002年 | 1591篇 |
2001年 | 1429篇 |
2000年 | 1106篇 |
1999年 | 986篇 |
1998年 | 792篇 |
1997年 | 723篇 |
1996年 | 641篇 |
1995年 | 657篇 |
1994年 | 616篇 |
1993年 | 482篇 |
1992年 | 474篇 |
1991年 | 429篇 |
1990年 | 351篇 |
1989年 | 358篇 |
1988年 | 328篇 |
1987年 | 285篇 |
1986年 | 261篇 |
1985年 | 482篇 |
1984年 | 479篇 |
1983年 | 366篇 |
1982年 | 410篇 |
1981年 | 400篇 |
1980年 | 375篇 |
1979年 | 349篇 |
1978年 | 300篇 |
1977年 | 270篇 |
1976年 | 204篇 |
1975年 | 126篇 |
排序方式: 共有10000条查询结果,搜索用时 62 毫秒
91.
92.
Pulmonary Lophomonas blattarum infection in patients with kidney allograft transplantation 总被引:3,自引:0,他引:3
Yong Wang Zheng Tang Shuming Ji Zhen Zhang Jinsong Chen Zhen Cheng Dongrui Cheng Zhihong Liu Leishi Li 《Transplant international》2006,19(12):1006-1013
The aim of the study was to analyse the clinical manifestation and management of pulmonary Lophomonas blattarum infection in four allograft transplantation recipients retrospectively. Four patients with pulmonary L. blattarum infection were diagnosed by using Fiberoptic bronchoscopy (FOB) and bronchoalveolar lavage (BAL) examination. Their clinical manifestation and management are summarized. Four cases of pulmonary L. blattarum were found during the period from the second month to the third month after transplantation. Concurring infection by other pathogens was found in three of them. Common initial symptoms included fever (>38 degrees C) without cough and breathlessness. Lower lobe shadowing could be found on chest X-ray. Body temperature decreased to the normal range in three patients and to 37.5 degrees C in the other one, after intravenous injection of metronidazole and tapering immunosuppressant. Radiological examination confirmed improved health condition of the patients afterwards. Two patients received repeated FOB and only dead L. blattarum was found. Pulmonary L. blattarum infection in allograft transplant recipients carry relatively obscure initial symptoms. Possible L. blattarum infection needs to be screened in post-transplantation pulmonary infection patients with similar symptoms, especially in those who respond poorly to anti-infection treatment. Microscopic examination of BAL fluid can help to identify pulmonary L. blattarum infection and metronidazole is an ideal treatment choice. 相似文献
93.
C. Ballet G. Roussey-Kesler J.-T. Aubin S. Brouard M. Giral P. Miqueu S. Louis S. van der Werf J.-P. Soulillou 《American journal of transplantation》2006,6(11):2796-2801
Rare kidney allograft recipients enjoy unaltered graft function years after interruption of their immunosuppressive treatment. To assess the extent to which this state of 'operational tolerance' (TOL) is specific to the graft and not the result of a global immunodeficiency, we analyzed the response of such patients following influenza vaccination. Hemagglutination inhibition titers and frequency of IFNgamma-secreting T cells were measured before 1 and 3 months after vaccination. The proportion of healthy volunteers (HV) responding to vaccine was significantly higher than that of immunosuppressed (IS) patients. Three 'TOL' patients presented a humoral response similar to that of HV, whereas the two others had a poor response, like the IS recipients. Although the small number of patients does not allow for definitive conclusions to be made, these data suggest that the status of tolerance may be heterogeneous, with some patients with a global immunodeficiency and others with an adapted response to vaccination. 相似文献
94.
95.
积极治疗节育手术并发症是搞好计划生育的一个重要环节。月经异常是宫内放置节育环的主要并发症,也是节育环停止使用的主要原因。近几年来本人采用消炎痛治疗官内放环后月经异常,取得了良好的效果。 相似文献
96.
DTF降茶氟剂降茶氟初步研究 总被引:9,自引:1,他引:8
王连方 《中国地方病防治杂志》2003,18(1):17-19
目的探讨DTF制剂降茶氟效果。方法在不同制茶方法程序中加入DTF制剂观察其降氟效果。结果在冲泡或煮沸(1.0g茶叶,200ml水量)沏茶中,0.2gDTF可使茶氟降低约60%,使茶水氟浓度由2.0~4.0mg/L降到1.0mg/L左右,茶液色、味、pH值无改变。结论DTF是1种有效的降茶氟剂。 相似文献
97.
98.
L. Matsuoka T. Shah S. Aswad S. Bunnapradist Y. Cho R. G. Mendez R. Mendez R. Selby 《American journal of transplantation》2006,6(6):1473-1478
The use of expanded criteria donors (ECD) has been proposed to help combat the discrepancy between organ availability and need. ECD kidneys are associated with delayed graft function (DGF) and worse long-term survival. The aim of this study is to evaluate the impact of pulsatile perfusion (PP) on DGF and graft survival in transplanted ECD kidneys. From January 2000 to December 2003, 4618 ECD kidney-alone transplants were reported to the United Network for Organ Sharing. PP was performed on 912 renal allografts. The prognostic factors of DGF were analyzed using multivariate logistic regression analysis. Risk factors for reduced allograft viability were greater in donors and recipients of PP kidneys. Three-year graft survival of ECD kidneys preserved with PP was similar to cold storage (CS) kidneys. The incidence of DGF in PP kidneys was significantly lower than CS kidneys (26% vs. 36%, p < 0.001). Despite having a greater number of risk factors for reduced graft viability, the ECD-PP kidneys had similar graft survival compared to ECD-CS kidneys. The use of PP, by decreasing the incidence of DGF, may possibly lead to lower overall costs and increased utilization of donor kidneys. 相似文献
99.
Coccidioidomycosis is an endemic fungal infection of the desert southwestern United States of particular concern for immunosuppressed renal transplant recipients. The clinical course of coccidioidomycosis can be severe in immunosuppressed patients, with high rates of dissemination and mortality, and antifungal prophylaxis is routinely administered to high-risk patients. We sought to determine the impact of coccidioidomycosis on patients who received their renal transplant at our hospital in Phoenix, Arizona. A retrospective records review of the first 205 patients who received a renal transplant between June 1999 and December 2003 identified 6 patients (3%) who had contracted coccidioidomycosis after transplantation. All six cases occurred more than 6 months after transplantation. Two of these six patients had disseminated coccidioidomycosis. Two patients, one with pulmonary infection and one with disseminated infection, died. None of the six patients with coccidioidomycosis after transplantation had identified risk factors before transplantation. No high-risk patient who received targeted antifungal prophylaxis had a reactivation of coccidioidomycosis after transplantation. Treatment for acute rejection and induction with antithymocyte globulin did not appear to increase the risk of subsequent coccidioidomycosis. 相似文献
100.
目的:了解包头市初次吸毒者与复吸者戒毒期间的生活质量。方法:用QOL-DA2.0量表对戒毒人员的生活质量进行调查。结果:初次吸毒者与复吸者各纬度进行t检验显示躯体功能纬度(t=10.51)、心理功能纬度(t=5.94)、症状及毒副作用纬度(t=6.41)、社会功能纬度(t=10.47)和总分(t=10.48)均有统计学意义(P<0.001),表明戒毒期间初次吸毒者的生活质量高于复吸者。结论:在戒毒期间初次吸毒者的生活质量较复吸者易改善。 相似文献